We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
TCF4
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Cluster
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Interacting gene
Number of interactions
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • INTERACTION

  • TCF4
IMMUNE CELL B-CELLS Show tissue menu
B-CELLS DENDRITIC CELLS GRANULOCYTES MONOCYTES NK-CELLS PROGENITORS T-CELLS TOTAL PBMC
Immune cell proteome
B-cells
B-CELLS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA:174.1 nTPM
Monaco:401.3 nTPM
Schmiedel:56.1 TPM

B-CELLS - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM 174.1
HPA sample nTPM
Memory B-cell
nTPM: 174.1
Samples: 6

Max nTPM: 204.7
Min nTPM: 125.4
P10809_1017 125.4
P10809_1025 204.7
P10809_1044 161.8
P10809_1063 204.2
P10809_1092 173.9
P10809_1105 174.7
Naive B-cell
nTPM: 147.6
Samples: 6

Max nTPM: 368.2
Min nTPM: 57.3
P10809_1011 57.3
P10809_1029 133.0
P10809_1048 368.2
P10809_1067 129.2
P10809_1091 86.0
P10809_1104 111.6

B-CELLS - Monaco RNA-seqi

RNA-Seq data generated by Monaco et al is reported as average nTPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max nTPM 401.3
Monaco sample nTPM
Exhausted memory B-cell
nTPM: 214.8
Samples: 4

Max nTPM: 271.3
Min nTPM: 129.2
RHH5310_R3677 238.0
RHH5218_R3590 220.7
RHH5247_R3619 271.3
RHH5276_R3648 129.2
Naive B-cell
nTPM: 186.7
Samples: 4

Max nTPM: 265.8
Min nTPM: 126.4
RHH5308_R3675 165.4
RHH5216_R3588 265.8
RHH5245_R3617 126.4
RHH5274_R3646 189.2
Non-switched memory B-cell
nTPM: 401.3
Samples: 4

Max nTPM: 530.1
Min nTPM: 333.7
RHH5309_R3676 348.7
RHH5217_R3589 392.7
RHH5246_R3618 530.1
RHH5275_R3647 333.7
Plasmablast
nTPM: 250.1
Samples: 4

Max nTPM: 293.3
Min nTPM: 212.6
RHH5312_R3679 212.6
RHH5220_R3592 268.8
RHH5249_R3621 293.3
RHH5278_R3650 225.6
Switched memory B-cell
nTPM: 316.3
Samples: 4

Max nTPM: 348.4
Min nTPM: 284.7
RHH5311_R3678 319.1
RHH5219_R3591 348.4
RHH5248_R3620 312.9
RHH5277_R3649 284.7

B-CELLS - Schmiedel RNA-seqi

RNA-Seq data generated by Schmiedel et al is reported as average TPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. TPM values of the individual samples are presented next to the box plot.

Max TPM 56.1
Schmiedel sample id TPM
Naive B-cell
TPM: 56.1
Samples: 91

Max TPM: 83.0
Min TPM: 39.2
B_CELL_NAIVE_1 83.0
B_CELL_NAIVE_2 80.5
B_CELL_NAIVE_3 79.1
B_CELL_NAIVE_4 76.0
B_CELL_NAIVE_5 74.9
B_CELL_NAIVE_6 72.7
B_CELL_NAIVE_7 70.8
B_CELL_NAIVE_8 70.5
B_CELL_NAIVE_9 68.0
B_CELL_NAIVE_10 66.1
B_CELL_NAIVE_11 66.1
B_CELL_NAIVE_12 65.5
B_CELL_NAIVE_13 64.8
B_CELL_NAIVE_14 64.3
B_CELL_NAIVE_15 63.7
B_CELL_NAIVE_16 63.2
B_CELL_NAIVE_17 63.1
B_CELL_NAIVE_18 62.1
B_CELL_NAIVE_19 62.1
B_CELL_NAIVE_20 62.0
B_CELL_NAIVE_21 61.2
B_CELL_NAIVE_22 61.1
B_CELL_NAIVE_23 60.2
B_CELL_NAIVE_24 60.1
B_CELL_NAIVE_25 60.0
B_CELL_NAIVE_26 59.2
B_CELL_NAIVE_27 59.0
B_CELL_NAIVE_28 58.9
B_CELL_NAIVE_29 58.6
B_CELL_NAIVE_30 58.3
B_CELL_NAIVE_31 57.8
B_CELL_NAIVE_32 57.8
B_CELL_NAIVE_33 57.6
B_CELL_NAIVE_34 57.6
B_CELL_NAIVE_35 57.5
B_CELL_NAIVE_36 57.5
B_CELL_NAIVE_37 57.4
B_CELL_NAIVE_38 57.3
B_CELL_NAIVE_39 57.2
B_CELL_NAIVE_40 57.1
B_CELL_NAIVE_41 57.0
B_CELL_NAIVE_42 57.0
B_CELL_NAIVE_43 56.3
B_CELL_NAIVE_44 56.1
B_CELL_NAIVE_45 56.1
B_CELL_NAIVE_46 55.8
B_CELL_NAIVE_47 55.4
B_CELL_NAIVE_48 55.3
B_CELL_NAIVE_49 55.1
B_CELL_NAIVE_50 54.6
B_CELL_NAIVE_51 54.4
B_CELL_NAIVE_52 54.3
B_CELL_NAIVE_53 54.2
B_CELL_NAIVE_54 54.2
B_CELL_NAIVE_55 54.1
B_CELL_NAIVE_56 53.8
B_CELL_NAIVE_57 53.5
B_CELL_NAIVE_58 53.3
B_CELL_NAIVE_59 53.0
B_CELL_NAIVE_60 52.3
B_CELL_NAIVE_61 52.1
B_CELL_NAIVE_62 51.9
B_CELL_NAIVE_63 51.8
B_CELL_NAIVE_64 51.4
B_CELL_NAIVE_65 50.5
B_CELL_NAIVE_66 50.0
B_CELL_NAIVE_67 49.7
B_CELL_NAIVE_68 49.2
B_CELL_NAIVE_69 49.1
B_CELL_NAIVE_70 49.1
B_CELL_NAIVE_71 48.6
B_CELL_NAIVE_72 48.3
B_CELL_NAIVE_73 48.1
B_CELL_NAIVE_74 47.3
B_CELL_NAIVE_75 47.2
B_CELL_NAIVE_76 47.1
B_CELL_NAIVE_77 47.0
B_CELL_NAIVE_78 46.9
B_CELL_NAIVE_79 46.8
B_CELL_NAIVE_80 46.8
B_CELL_NAIVE_81 46.8
B_CELL_NAIVE_82 46.4
B_CELL_NAIVE_83 45.2
B_CELL_NAIVE_84 44.9
B_CELL_NAIVE_85 44.4
B_CELL_NAIVE_86 44.1
B_CELL_NAIVE_87 43.4
B_CELL_NAIVE_88 43.0
B_CELL_NAIVE_89 42.8
B_CELL_NAIVE_90 39.9
B_CELL_NAIVE_91 39.2
Show allShow less

Contact

  • NEWS ARTICLES
  • PRESS ROOM

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org