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MT-CO2
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                                  • MT-CO2
                                  PATHOLOGY LIVER CANCER Show tissue menu
                                  BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
                                  MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
                                  ANTIBODIES
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                                  Dictionary
                                  Liver cancer
                                  Human pathology
                                  Liver cancer
                                  LIVER CANCER - Interactive survival scatter ploti

                                  The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

                                  The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

                                  Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

                                  Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

                                  & Survival analysisi

                                  Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

                                  MT-CO2 is prognostic, high expression is favorable in liver cancer


                                  Stage:


                                  0 1 2 3 4 5 6 7 8 910Time after diagnosis (years)0.05.0k10k15k20k25k30k35kExpression level (FPKM)Dead (n=130)Alive (n=235)9.0e+3Density dead9.5e+3Density alive0.81Density dead under cut off1.5Density dead over cut off0.00.10.20.30.40.60.81.0P score0.50.00.60.40.20.81.0Medain separationP scoreDead median separationCut off
                                  0.00.10.20.30.40.50.60.70.80.91.0Survival probability 0 1 2 3 4 5 6 7 8 910Time (years)Low expression (n=118)High expression (n=247)
                                  Survival analysis
                                  Current cut offi

                                  Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

                                  :
                                  Best expression cut offi

                                  Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

                                  When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

                                  : 7420.05
                                  Median expressioni

                                  Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

                                  : 9329.94
                                  Median follow up timei

                                  Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

                                  : 1.63
                                  P scorei

                                  Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

                                  0.00029
                                  5-year survival highi

                                  5-year survival for patients with higher expression than the expression cutoff.

                                  For melanoma and glioma, 3-year survival is shown.

                                  56%
                                  5-year survival lowi

                                  5-year survival for patients with lower expression than the expression cutoff.

                                  For melanoma and glioma, 3-year survival is shown.

                                  28%
                                  TCGA RNA samplesi

                                  RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

                                  Average FPKM 10745.2
                                  Number of samples 365
                                  Samples
                                  Sample Description FPKM
                                  TCGA-DD-AAEB-01A 60 years, male, asian, stage:i, alive, 478 days 39217.4
                                  TCGA-DD-AACE-01A 62 years, male, asian, stage:i, alive, 2184 days 38233.0
                                  TCGA-DD-A4NG-01A 77 years, male, white, stage:iiia, dead, 802 days 37382.8
                                  TCGA-MR-A8JO-01A 34 years, male, white, stage:i, alive, 330 days 36179.6
                                  TCGA-WX-AA47-01A 33 years, female, white, stage:iiia, dead, 556 days 34817.3
                                  TCGA-WQ-A9G7-01A female, white, alive, 30 days 28315.9
                                  TCGA-RC-A7SH-01A 42 years, male, asian, stage:ii, alive, 468 days 28006.7
                                  TCGA-5R-AA1D-01A 17 years, female, white, stage:iiia, alive, 449 days 27623.1
                                  TCGA-DD-AAD6-01A 66 years, male, asian, stage:iiia, alive, 672 days 27196.6
                                  TCGA-DD-A3A6-01A 72 years, female, white, stage:ii, dead, 3258 days 26571.6
                                  TCGA-G3-A3CJ-01A 52 years, male, american indian or alaska native, stage:ii, alive, 594 days 26185.3
                                  TCGA-DD-A3A2-01A 76 years, female, white, stage:i, dead, 2131 days 25478.4
                                  TCGA-BC-A10Q-01A 72 years, female, white, dead, 1135 days 25351.9
                                  TCGA-DD-AACD-01A 48 years, male, asian, stage:i, dead, 381 days 24639.8
                                  TCGA-2Y-A9H3-01A 45 years, male, white, stage:ii, alive, 1516 days 23781.4
                                  TCGA-DD-AAE3-01A 50 years, male, asian, stage:i, alive, 566 days 23161.6
                                  TCGA-EP-A26S-01A 70 years, male, white, stage:i, alive, 608 days 23018.6
                                  TCGA-ED-A7PZ-01A 61 years, male, asian, stage:ii, alive, 6 days 22981.0
                                  TCGA-EP-A3JL-01A 76 years, male, white, stage:i, alive, 303 days 22564.0
                                  TCGA-NI-A4U2-01A 71 years, male, white, stage:iiia, dead, 1791 days 22122.6
                                  TCGA-XR-A8TD-01A 49 years, female, white, stage:iiib, alive, 1030 days 21947.8
                                  TCGA-DD-A4NI-01A 67 years, male, white, stage:ii, alive, 816 days 21671.1
                                  TCGA-WJ-A86L-01A 68 years, female, white, stage:i, alive, 345 days 21228.1
                                  TCGA-DD-AADS-01A 63 years, male, asian, stage:i, alive, 474 days 20173.1
                                  TCGA-DD-AAEA-01A 65 years, male, asian, stage:i, alive, 575 days 19883.7
                                  TCGA-CC-A8HV-01A 51 years, female, asian, stage:ii, dead, 279 days 19759.8
                                  TCGA-DD-A118-01A 77 years, female, white, stage:ii, alive, 3437 days 19562.6
                                  TCGA-DD-AACJ-01A 75 years, male, asian, stage:ii, alive, 2102 days 19055.7
                                  TCGA-DD-AACX-01A 66 years, male, asian, stage:ii, alive, 170 days 18637.3
                                  TCGA-2Y-A9H2-01A 64 years, female, white, stage:i, alive, 1731 days 18592.1
                                  TCGA-DD-AADF-01A 64 years, female, asian, stage:i, dead, 115 days 18536.6
                                  TCGA-RC-A6M4-01A 74 years, female, white, stage:iiia, alive, 22 days 18188.5
                                  TCGA-DD-A73A-01A 71 years, male, white, stage:i, alive, 728 days 17947.3
                                  TCGA-RC-A6M5-01A 20 years, female, white, stage:iva, alive, 15 days 17940.4
                                  TCGA-DD-A1EC-01A 20 years, female, white, stage:i, alive, 602 days 17840.0
                                  TCGA-DD-A3A7-01A 67 years, male, stage:iiib, dead, 419 days 17483.3
                                  TCGA-G3-A7M8-01A 31 years, male, asian, stage:i, alive, 430 days 17462.6
                                  TCGA-DD-A4NB-01A 25 years, male, white, stage:i, alive, 989 days 17418.0
                                  TCGA-DD-AADR-01A 58 years, male, asian, stage:i, alive, 2028 days 17410.4
                                  TCGA-BD-A3ER-01A 62 years, male, white, stage:ii, alive, 1115 days 17334.5
                                  TCGA-ED-A7PX-01A 48 years, female, asian, stage:ii, alive, 6 days 17271.6
                                  TCGA-G3-A25Z-01A 58 years, male, asian, stage:i, alive, 655 days 17094.8
                                  TCGA-CC-A5UC-01A 63 years, male, asian, stage:iiia, dead, 347 days 17049.8
                                  TCGA-DD-AADU-01A 60 years, male, asian, stage:ii, alive, 554 days 17035.2
                                  TCGA-DD-AAVP-01A 48 years, male, asian, stage:i, alive, 2752 days 16844.0
                                  TCGA-G3-A3CI-01A 71 years, male, white, stage:i, alive, 180 days 16752.7
                                  TCGA-CC-A8HT-01A 74 years, male, asian, stage:iiia, dead, 140 days 16508.2
                                  TCGA-NI-A8LF-01A 74 years, male, white, stage:i, alive, 799 days 16469.2
                                  TCGA-RC-A7SF-01A 66 years, male, asian, stage:i, alive, 579 days 16443.9
                                  TCGA-2Y-A9H8-01A 85 years, female, white, dead, 633 days 16416.5
                                  TCGA-CC-A7IF-01A 59 years, male, asian, stage:iiia, dead, 649 days 16394.7
                                  TCGA-ZP-A9D4-01A 64 years, female, white, alive, 395 days 16253.5
                                  TCGA-DD-AAEH-01A 73 years, male, asian, stage:i, alive, 784 days 16184.4
                                  TCGA-CC-A7IL-01A 61 years, male, asian, stage:iiia, dead, 278 days 16148.0
                                  TCGA-WQ-AB4B-01A 62 years, male, white, stage:ii, alive, 395 days 15958.7
                                  TCGA-BC-A10T-01A 76 years, male, white, dead, 837 days 15943.1
                                  TCGA-KR-A7K8-01A 57 years, male, stage:i, alive, 906 days 15902.4
                                  TCGA-BC-A10Z-01A 62 years, female, white, stage:i, dead, 34 days 15900.6
                                  TCGA-RC-A7SB-01A 53 years, male, asian, stage:ii, alive, 588 days 15779.1
                                  TCGA-BD-A2L6-01A 69 years, male, white, alive, 1363 days 15778.5
                                  TCGA-DD-AAW2-01A 69 years, male, asian, stage:i, alive, 1855 days 15738.7
                                  TCGA-WX-AA46-01A 62 years, male, white, stage:ii, alive, 756 days 15417.7
                                  TCGA-DD-AAW3-01A 69 years, male, asian, stage:i, alive, 1633 days 15327.4
                                  TCGA-DD-AAE4-01A 49 years, female, asian, stage:i, alive, 608 days 15176.8
                                  TCGA-BC-A3KF-01A 66 years, female, white, stage:i, alive, 8 days 15105.9
                                  TCGA-DD-A1EB-01A 72 years, female, stage:i, alive, 2017 days 15093.1
                                  TCGA-CC-A7IE-01A 57 years, male, asian, stage:iiia, dead, 217 days 15004.3
                                  TCGA-FV-A3R3-01A 38 years, female, white, stage:i, dead, 366 days 14992.6
                                  TCGA-BC-A216-01A 62 years, female, white, stage:iiia, alive, 1351 days 14986.2
                                  TCGA-DD-AACA-01A 65 years, male, asian, stage:i, alive, 2301 days 14971.0
                                  TCGA-HP-A5MZ-01A 62 years, male, stage:i, dead, 91 days 14876.3
                                  TCGA-XR-A8TF-01A 74 years, male, white, stage:i, dead, 693 days 14821.0
                                  TCGA-DD-A1EK-01A 64 years, female, white, stage:ivb, dead, 558 days 14666.2
                                  TCGA-EP-A2KC-01A 62 years, male, black or african american, stage:i, dead, 19 days 14651.3
                                  TCGA-DD-A4NF-01A 72 years, male, white, stage:i, alive, 942 days 14647.2
                                  TCGA-2Y-A9GU-01A 55 years, female, white, stage:i, alive, 1939 days 14642.3
                                  TCGA-DD-A39Z-01A 43 years, female, stage:ii, dead, 601 days 14502.6
                                  TCGA-DD-AACI-01A 69 years, male, asian, stage:ii, alive, 1618 days 14448.5
                                  TCGA-CC-A3MA-01A 61 years, male, asian, stage:iiia, dead, 303 days 14428.6
                                  TCGA-DD-AAE6-01A 59 years, female, asian, stage:i, alive, 141 days 14089.5
                                  TCGA-DD-A73D-01A 68 years, female, white, stage:ii, alive, 693 days 14062.9
                                  TCGA-DD-AAVY-01A 56 years, male, asian, stage:iiia, alive, 1970 days 14056.6
                                  TCGA-DD-AAD5-01A 54 years, male, asian, stage:i, alive, 1345 days 14008.5
                                  TCGA-G3-AAV1-01A 51 years, male, asian, stage:iiic, dead, 359 days 13797.5
                                  TCGA-DD-A4NQ-01A 60 years, male, white, stage:ii, dead, 373 days 13767.7
                                  TCGA-G3-A5SJ-01A 59 years, male, white, stage:i, alive, 698 days 13715.8
                                  TCGA-DD-A73B-01A 72 years, female, white, stage:i, dead, 283 days 13609.6
                                  TCGA-2Y-A9GW-01A 64 years, male, white, stage:i, dead, 1271 days 13548.1
                                  TCGA-G3-A25T-01A 45 years, female, white, stage:iiia, alive, 1553 days 13472.4
                                  TCGA-CC-5259-01A 60 years, female, asian, stage:iiic, alive, 250 days 13397.2
                                  TCGA-2Y-A9GZ-01A 82 years, female, white, stage:ii, dead, 848 days 13378.1
                                  TCGA-ZS-A9CG-01A 55 years, male, white, stage:ii, alive, 341 days 13320.3
                                  TCGA-BC-A10R-01A 66 years, female, white, dead, 308 days 13316.0
                                  TCGA-2Y-A9H4-01A 68 years, male, black or african american, stage:i, alive, 1452 days 13241.1
                                  TCGA-G3-AAV5-01A 67 years, male, white, stage:ii, alive, 354 days 13208.4
                                  TCGA-DD-AACO-01A 40 years, male, asian, stage:i, alive, 1876 days 13132.7
                                  TCGA-DD-A116-01A 68 years, male, asian, stage:iiia, dead, 1622 days 13106.5
                                  TCGA-DD-AACT-01A 69 years, female, asian, stage:i, alive, 1562 days 13076.8
                                  TCGA-DD-A1EE-01A 73 years, male, white, stage:iiia, dead, 349 days 12969.7
                                  TCGA-G3-A3CH-01A 53 years, male, asian, stage:iiia, alive, 780 days 12862.7
                                  TCGA-K7-AAU7-01A 61 years, male, white, stage:ii, alive, 359 days 12812.9
                                  TCGA-G3-A5SM-01A 58 years, male, white, stage:ii, alive, 520 days 12796.0
                                  TCGA-KR-A7K0-01A 65 years, male, white, stage:i, dead, 65 days 12789.2
                                  TCGA-KR-A7K2-01A 64 years, male, white, stage:i, alive, 829 days 12772.5
                                  TCGA-DD-AADL-01A 58 years, male, asian, stage:i, alive, 636 days 12553.7
                                  TCGA-DD-AAW1-01A 55 years, male, asian, stage:iiia, alive, 1989 days 12543.4
                                  TCGA-DD-AAE1-01A 52 years, male, asian, stage:i, alive, 552 days 12272.2
                                  TCGA-G3-A3CG-01A 80 years, male, white, stage:i, alive, 673 days 12175.8
                                  TCGA-G3-A5SL-01A 70 years, male, white, stage:ii, alive, 621 days 11999.4
                                  TCGA-MI-A75E-01A 61 years, male, white, stage:iiic, alive, 507 days 11940.2
                                  TCGA-O8-A75V-01A 54 years, male, stage:i, alive, 538 days 11934.0
                                  TCGA-MR-A520-01A 58 years, male, white, stage:i, alive, 229 days 11931.8
                                  TCGA-EP-A2KB-01A 46 years, female, white, stage:i, dead, 596 days 11915.3
                                  TCGA-G3-A5SK-01A 58 years, male, white, stage:i, alive, 744 days 11809.7
                                  TCGA-G3-A7M7-01A 65 years, male, white, stage:i, alive, 361 days 11751.7
                                  TCGA-LG-A9QC-01A 48 years, male, white, stage:i, alive, 425 days 11692.6
                                  TCGA-DD-A4NJ-01A 54 years, female, white, stage:ii, alive, 928 days 11663.1
                                  TCGA-UB-AA0V-01A 69 years, female, white, stage:i, alive, 314 days 11625.9
                                  TCGA-QA-A7B7-01A 48 years, male, black or african american, stage:ii, alive, 94 days 11597.3
                                  TCGA-DD-A1EL-01A 23 years, male, black or african american, stage:ii, dead, 415 days 11583.2
                                  TCGA-DD-AADG-01A 70 years, male, asian, stage:iiia, alive, 1145 days 11565.9
                                  TCGA-EP-A2KA-01A 52 years, female, white, stage:iiia, dead, 627 days 11559.3
                                  TCGA-DD-AACW-01A 43 years, male, asian, stage:i, alive, 1424 days 11482.7
                                  TCGA-DD-AAED-01A 51 years, male, asian, stage:i, alive, 763 days 11464.4
                                  TCGA-CC-A9FS-01A 55 years, male, asian, stage:ii, alive, 211 days 11390.0
                                  TCGA-CC-A3MB-01A 36 years, male, asian, stage:iiia, dead, 315 days 11371.2
                                  TCGA-DD-A115-01A 53 years, male, white, stage:iiia, dead, 2542 days 11289.0
                                  TCGA-BC-A10S-01A 81 years, male, white, dead, 1423 days 11280.8
                                  TCGA-ED-A7PY-01A 20 years, female, asian, stage:ii, alive, 390 days 11261.3
                                  TCGA-WX-AA44-01A 64 years, female, white, stage:i, alive, 615 days 11259.4
                                  TCGA-DD-A3A3-01A 45 years, male, asian, stage:i, dead, 535 days 11253.9
                                  TCGA-PD-A5DF-01A 58 years, female, white, stage:iiib, dead, 639 days 11168.7
                                  TCGA-DD-AAC9-01A 51 years, male, asian, stage:i, alive, 347 days 11095.4
                                  TCGA-DD-AAE2-01A 51 years, male, asian, stage:i, alive, 638 days 11034.2
                                  TCGA-DD-A73G-01A 73 years, female, white, stage:i, alive, 3478 days 10989.1
                                  TCGA-DD-A113-01A 55 years, female, white, stage:ii, alive, 2425 days 10855.4
                                  TCGA-2Y-A9H9-01A 70 years, male, white, stage:i, alive, 697 days 10747.8
                                  TCGA-DD-AAD8-01A 73 years, female, asian, stage:i, alive, 1219 days 10675.2
                                  TCGA-DD-AAE9-01A 69 years, male, asian, stage:i, alive, 722 days 10671.3
                                  TCGA-RC-A7S9-01A 47 years, female, asian, stage:i, alive, 640 days 10590.6
                                  TCGA-GJ-A3OU-01A 59 years, male, white, stage:i, alive, 879 days 10577.7
                                  TCGA-CC-A7IH-01A 58 years, male, asian, stage:iiia, alive, 365 days 10548.1
                                  TCGA-DD-A3A8-01A 75 years, male, white, stage:ii, dead, 11 days 10538.3
                                  TCGA-DD-AACZ-01A 63 years, female, asian, stage:i, dead, 171 days 10516.9
                                  TCGA-MI-A75H-01A 77 years, male, white, alive, 747 days 10506.9
                                  TCGA-ED-A7XO-01A 29 years, male, asian, stage:iiia, alive, 427 days 10468.2
                                  TCGA-DD-AACF-01A 68 years, male, asian, stage:i, dead, 365 days 10460.9
                                  TCGA-BC-A110-01A 51 years, female, black or african american, dead, 2116 days 10438.2
                                  TCGA-CC-A5UD-01A 45 years, male, asian, stage:iiia, dead, 304 days 10304.1
                                  TCGA-2Y-A9GX-01A 68 years, male, white, stage:i, alive, 2442 days 10247.6
                                  TCGA-DD-AADA-01A 66 years, female, asian, stage:i, alive, 1233 days 10239.1
                                  TCGA-DD-A1EA-01A 68 years, male, asian, stage:ii, alive, 2415 days 10207.4
                                  TCGA-FV-A495-01A 51 years, female, white, stage:ii, alive, 1 days 10164.5
                                  TCGA-UB-AA0U-01A 60 years, male, white, stage:ii, alive, 327 days 10154.5
                                  TCGA-G3-A6UC-01A 65 years, male, white, stage:iiib, alive, 671 days 10135.7
                                  TCGA-BD-A3EP-01A 76 years, female, black or african american, stage:i, alive, 409 days 10108.4
                                  TCGA-DD-AAVR-01A 44 years, male, asian, stage:i, alive, 2513 days 10090.9
                                  TCGA-DD-AADD-01A 51 years, male, asian, stage:i, alive, 1231 days 10061.4
                                  TCGA-DD-AADM-01A 58 years, male, asian, stage:ii, dead, 12 days 10058.8
                                  TCGA-DD-AAE0-01A 45 years, female, asian, stage:iiia, alive, 555 days 10045.4
                                  TCGA-K7-A5RG-01A 66 years, male, black or african american, stage:i, alive, 519 days 10041.4
                                  TCGA-DD-AACQ-01A 50 years, male, asian, stage:ii, dead, 432 days 10029.1
                                  TCGA-BC-A10X-01A 52 years, female, white, stage:iiia, dead, 770 days 9974.1
                                  TCGA-2Y-A9GY-01A 64 years, female, white, stage:ii, dead, 757 days 9968.0
                                  TCGA-2Y-A9H6-01A 68 years, female, white, stage:i, alive, 357 days 9880.5
                                  TCGA-BC-4072-01B 74 years, female, white, stage:iiia, dead, 1490 days 9862.1
                                  TCGA-G3-A5SI-01A 44 years, male, asian, stage:ii, dead, 768 days 9845.7
                                  TCGA-DD-A4NS-01A 62 years, female, white, stage:i, dead, 2456 days 9829.5
                                  TCGA-DD-A4NK-01A 80 years, female, white, stage:iiia, dead, 1210 days 9781.5
                                  TCGA-MI-A75C-01A 64 years, male, white, stage:i, alive, 291 days 9697.6
                                  TCGA-RG-A7D4-01A 69 years, male, black or african american, stage:ii, alive, 1098 days 9620.8
                                  TCGA-DD-A3A4-01A 37 years, male, white, stage:iiia, dead, 612 days 9561.4
                                  TCGA-FV-A23B-01A 70 years, female, white, stage:ii, dead, 1852 days 9550.1
                                  TCGA-DD-A3A1-01A 65 years, male, stage:iiia, dead, 233 days 9541.5
                                  TCGA-DD-AAEE-01A 55 years, male, asian, stage:i, alive, 810 days 9503.2
                                  TCGA-DD-A4NE-01A 75 years, female, white, stage:iiia, dead, 660 days 9502.2
                                  TCGA-ZS-A9CF-01A 64 years, male, white, stage:ii, alive, 2412 days 9485.9
                                  TCGA-DD-AADN-01A 59 years, male, asian, stage:i, alive, 898 days 9485.5
                                  TCGA-DD-AADK-01A 68 years, female, asian, stage:ii, alive, 1049 days 9428.7
                                  TCGA-5C-A9VG-01A 58 years, male, white, stage:ii, alive, 328 days 9410.2
                                  TCGA-DD-AACL-01A 66 years, female, asian, stage:i, dead, 107 days 9355.0
                                  TCGA-CC-A3MC-01A 54 years, male, asian, stage:iiia, alive, 363 days 9342.2
                                  TCGA-G3-A25S-01A 64 years, male, white, stage:i, dead, 416 days 9329.9
                                  TCGA-BC-A10U-01A 69 years, male, white, dead, 837 days 9319.9
                                  TCGA-BC-A3KG-01A 68 years, female, white, stage:ii, alive, 680 days 9310.6
                                  TCGA-ED-A4XI-01A 58 years, male, asian, stage:ii, alive, 819 days 9258.4
                                  TCGA-ED-A8O6-01A 50 years, female, asian, stage:iiia, dead, 56 days 9258.4
                                  TCGA-DD-AAD2-01A 66 years, male, asian, stage:i, alive, 658 days 9223.4
                                  TCGA-DD-AAVV-01A 56 years, male, asian, stage:ii, alive, 2455 days 9220.0
                                  TCGA-ZS-A9CD-01A 73 years, male, white, stage:ii, dead, 1386 days 9170.4
                                  TCGA-DD-A4NP-01A 32 years, male, white, stage:i, alive, 3308 days 9126.6
                                  TCGA-LG-A9QD-01A 68 years, male, white, stage:iiia, alive, 366 days 9086.4
                                  TCGA-G3-A7M5-01A 76 years, male, asian, stage:i, alive, 447 days 9075.8
                                  TCGA-2Y-A9GV-01A 54 years, female, white, stage:i, dead, 2532 days 9049.6
                                  TCGA-DD-A119-01A 40 years, male, asian, stage:iv, dead, 223 days 9030.8
                                  TCGA-2Y-A9H5-01A 59 years, female, white, stage:i, dead, 555 days 8997.5
                                  TCGA-CC-A7IG-01A 47 years, male, asian, stage:ii, dead, 299 days 8995.1
                                  TCGA-BC-A217-01A 75 years, female, white, stage:ii, dead, 1397 days 8963.9
                                  TCGA-DD-A4NV-01A 61 years, male, white, stage:iiia, alive, 2398 days 8836.0
                                  TCGA-DD-A1ED-01A 68 years, male, white, stage:i, alive, 2301 days 8764.4
                                  TCGA-XR-A8TC-01A 43 years, female, white, stage:i, alive, 1339 days 8723.6
                                  TCGA-DD-A4ND-01A 56 years, female, white, stage:i, alive, 2746 days 8701.9
                                  TCGA-DD-AADJ-01A 70 years, female, asian, stage:i, alive, 1066 days 8687.4
                                  TCGA-DD-A3A5-01A 66 years, female, white, stage:iii, dead, 3125 days 8640.2
                                  TCGA-BW-A5NO-01A 50 years, male, black or african american, stage:iiia, alive, 20 days 8578.1
                                  TCGA-5R-AAAM-01A 65 years, female, white, stage:ii, dead, 46 days 8577.4
                                  TCGA-DD-AAD0-01A 73 years, female, asian, stage:i, alive, 137 days 8562.0
                                  TCGA-DD-A4NO-01A 66 years, male, white, stage:i, alive, 2245 days 8536.8
                                  TCGA-MI-A75G-01A 63 years, male, white, stage:ii, alive, 698 days 8521.3
                                  TCGA-2Y-A9H1-01A 58 years, male, white, stage:i, dead, 1229 days 8485.3
                                  TCGA-DD-AAEI-01A 72 years, male, asian, stage:i, alive, 1531 days 8438.0
                                  TCGA-DD-A73E-01A 66 years, male, white, stage:i, alive, 44 days 8432.9
                                  TCGA-G3-AAV2-01A 50 years, male, white, stage:i, alive, 372 days 8420.9
                                  TCGA-DD-A39W-01A 29 years, female, white, stage:iii, dead, 827 days 8405.8
                                  TCGA-BC-A69I-01A 69 years, male, white, stage:i, alive, 387 days 8385.9
                                  TCGA-G3-AAV4-01A 83 years, female, white, stage:i, dead, 27 days 8369.4
                                  TCGA-G3-A25U-01A 63 years, female, asian, stage:i, alive, 1636 days 8359.9
                                  TCGA-ED-A82E-01A 60 years, female, asian, stage:iiia, alive, 408 days 8356.4
                                  TCGA-ED-A7XP-01A 53 years, female, asian, stage:ii, alive, 400 days 8342.6
                                  TCGA-ZP-A9D1-01A 56 years, female, white, alive, 21 days 8303.7
                                  TCGA-3K-AAZ8-01A 65 years, male, black or african american, stage:iiib, alive, 396 days 8280.9
                                  TCGA-G3-A3CK-01A 61 years, male, asian, stage:i, alive, 585 days 8278.5
                                  TCGA-G3-AAUZ-01A 48 years, male, stage:i, alive, 480 days 8245.6
                                  TCGA-DD-AACP-01A 65 years, male, asian, stage:i, alive, 415 days 8232.2
                                  TCGA-ZP-A9CY-01A 66 years, female, white, alive, 782 days 8225.3
                                  TCGA-DD-AAEG-01A 59 years, female, asian, stage:i, alive, 719 days 8213.1
                                  TCGA-DD-A1EJ-01A 71 years, female, white, stage:iiic, dead, 1005 days 8168.5
                                  TCGA-DD-AADB-01A 51 years, male, asian, stage:i, alive, 1242 days 8153.4
                                  TCGA-2Y-A9H0-01A 49 years, male, white, stage:iiia, alive, 3675 days 8126.7
                                  TCGA-DD-AAVU-01A 46 years, male, asian, stage:ii, alive, 2202 days 8078.4
                                  TCGA-FV-A4ZP-01A 78 years, male, white, stage:iiia, dead, 2486 days 8067.7
                                  TCGA-DD-AACY-01A 61 years, male, asian, stage:i, alive, 1450 days 8018.6
                                  TCGA-DD-AAVQ-01A 38 years, male, asian, stage:i, alive, 2728 days 7976.1
                                  TCGA-DD-A73F-01A 77 years, female, white, stage:i, alive, 1085 days 7959.4
                                  TCGA-K7-A5RF-01A 64 years, male, white, stage:i, alive, 631 days 7925.0
                                  TCGA-DD-A11A-01A 67 years, male, black or african american, stage:i, alive, 79 days 7881.1
                                  TCGA-DD-A4NH-01A 65 years, female, white, stage:iiib, alive, 917 days 7856.8
                                  TCGA-DD-A4NA-01A 67 years, female, white, stage:iiic, alive, 1008 days 7768.5
                                  TCGA-DD-A4NL-01A 46 years, male, white, stage:i, alive, 1711 days 7757.0
                                  TCGA-DD-AACG-01A 52 years, male, asian, stage:ii, dead, 469 days 7740.9
                                  TCGA-ZP-A9D0-01A 67 years, female, black or african american, alive, 1091 days 7655.1
                                  TCGA-G3-AAV3-01A 58 years, female, white, stage:ii, alive, 412 days 7648.4
                                  TCGA-BC-A112-01A 80 years, male, white, dead, 153 days 7644.7
                                  TCGA-ZP-A9CV-01A 59 years, male, white, dead, 1088 days 7594.0
                                  TCGA-DD-AAVX-01A 38 years, male, asian, stage:ii, alive, 1570 days 7562.9
                                  TCGA-KR-A7K7-01A 61 years, female, white, stage:ii, alive, 951 days 7487.3
                                  TCGA-5R-AA1C-01A 57 years, male, white, stage:ii, alive, 520 days 7430.4
                                  TCGA-2Y-A9HA-01A 70 years, male, white, stage:ii, dead, 36 days 7409.7
                                  TCGA-DD-A4NR-01A 85 years, female, white, stage:i, dead, 9 days 7360.6
                                  TCGA-5C-A9VH-01A 70 years, male, white, stage:i, alive, 322 days 7339.4
                                  TCGA-DD-AADO-01A 55 years, male, asian, stage:i, alive, 453 days 7322.5
                                  TCGA-DD-A11D-01A 57 years, female, white, stage:i, dead, 1560 days 7285.4
                                  TCGA-DD-AADP-01A 45 years, male, asian, stage:i, alive, 458 days 7252.7
                                  TCGA-2Y-A9HB-01A 66 years, male, stage:i, alive, 260 days 7222.5
                                  TCGA-2Y-A9GT-01A 51 years, male, white, stage:i, dead, 1624 days 7217.7
                                  TCGA-DD-AAD3-01A 43 years, male, asian, stage:i, alive, 1295 days 7185.3
                                  TCGA-DD-AACV-01A 53 years, male, asian, stage:i, alive, 1531 days 7139.0
                                  TCGA-FV-A496-01A 84 years, female, white, stage:i, alive, 10 days 7121.5
                                  TCGA-DD-A3A9-01A 64 years, female, white, stage:ivb, dead, 931 days 7053.3
                                  TCGA-DD-A11B-01A 73 years, male, white, stage:i, dead, 14 days 7006.4
                                  TCGA-4R-AA8I-01A 66 years, male, white, stage:ii, dead, 262 days 6983.6
                                  TCGA-G3-AAV0-01A 58 years, male, asian, stage:i, alive, 476 days 6972.0
                                  TCGA-DD-A1EG-01A 77 years, male, white, stage:i, dead, 1372 days 6900.9
                                  TCGA-BC-A5W4-01A 69 years, male, white, stage:iiia, dead, 547 days 6896.7
                                  TCGA-CC-A5UE-01A 48 years, male, asian, stage:iiib, dead, 272 days 6890.4
                                  TCGA-EP-A12J-01A 63 years, male, black or african american, stage:i, alive, 570 days 6888.1
                                  TCGA-DD-AACH-01A 69 years, male, asian, stage:ii, dead, 195 days 6865.9
                                  TCGA-CC-A123-01A 24 years, female, asian, stage:iiia, alive, 219 days 6854.7
                                  TCGA-G3-A25V-01A 68 years, male, white, stage:i, alive, 860 days 6844.9
                                  TCGA-CC-A7IK-01A 59 years, male, asian, stage:iiia, dead, 262 days 6828.7
                                  TCGA-DD-AAVW-01A 35 years, male, asian, stage:i, alive, 2317 days 6798.8
                                  TCGA-DD-AACC-01A 61 years, male, asian, stage:i, dead, 1685 days 6774.8
                                  TCGA-DD-AADI-01A 43 years, female, asian, stage:i, alive, 1085 days 6745.5
                                  TCGA-UB-A7MF-01A 57 years, male, white, stage:iiia, dead, 214 days 6715.0
                                  TCGA-5C-AAPD-01A 61 years, male, asian, stage:ii, alive, 20 days 6679.8
                                  TCGA-DD-AADY-01A 55 years, female, asian, stage:i, alive, 555 days 6678.4
                                  TCGA-ED-A97K-01A 54 years, male, asian, stage:iiia, alive, 6 days 6631.3
                                  TCGA-DD-A4NN-01A 56 years, female, white, stage:i, dead, 899 days 6550.2
                                  TCGA-K7-A6G5-01A 66 years, male, white, stage:i, alive, 512 days 6506.0
                                  TCGA-CC-5260-01A 61 years, female, asian, stage:iiic, dead, 87 days 6468.9
                                  TCGA-DD-AADC-01A 53 years, male, asian, stage:i, dead, 425 days 6467.8
                                  TCGA-XR-A8TG-01A 59 years, male, white, stage:i, alive, 898 days 6465.2
                                  TCGA-DD-AA3A-01A 81 years, female, white, stage:i, dead, 410 days 6458.4
                                  TCGA-G3-A7M6-01A 60 years, female, white, stage:i, alive, 632 days 6423.9
                                  TCGA-DD-A1EF-01A 57 years, female, white, stage:i, dead, 394 days 6293.2
                                  TCGA-MI-A75I-01A 61 years, male, black or african american, alive, 630 days 6208.4
                                  TCGA-CC-A8HS-01A 18 years, male, asian, stage:iiic, dead, 300 days 6201.2
                                  TCGA-CC-5262-01A 67 years, male, asian, stage:iiic, dead, 103 days 6145.9
                                  TCGA-DD-A1EH-01A 23 years, male, white, stage:iii, alive, 1495 days 6128.7
                                  TCGA-ED-A8O5-01A 59 years, female, asian, stage:iiia, alive, 406 days 6110.1
                                  TCGA-DD-AACS-01A 39 years, male, asian, stage:i, alive, 1804 days 6073.8
                                  TCGA-2Y-A9GS-01A 58 years, male, white, dead, 724 days 6021.8
                                  TCGA-DD-AACB-01A 74 years, female, asian, stage:i, alive, 2324 days 6008.9
                                  TCGA-DD-AADQ-01A 59 years, male, asian, stage:ii, alive, 436 days 5993.9
                                  TCGA-DD-AAVS-01A 56 years, male, asian, stage:i, alive, 1823 days 5975.3
                                  TCGA-DD-AAVZ-01A 38 years, male, asian, stage:i, alive, 1900 days 5972.7
                                  TCGA-DD-AAE7-01A 72 years, male, asian, stage:i, alive, 644 days 5914.4
                                  TCGA-G3-AAV7-01A 38 years, male, asian, stage:ii, alive, 361 days 5897.6
                                  TCGA-DD-AADW-01A 48 years, male, asian, stage:i, alive, 587 days 5866.5
                                  TCGA-ES-A2HS-01A 80 years, male, white, stage:i, dead, 688 days 5834.4
                                  TCGA-ZS-A9CE-01A 79 years, female, white, stage:ii, alive, 1241 days 5832.8
                                  TCGA-ED-A627-01A 74 years, male, white, stage:i, alive, 423 days 5830.6
                                  TCGA-HP-A5N0-01A 88 years, female, dead, 1147 days 5829.8
                                  TCGA-DD-AAEK-01A 51 years, male, asian, stage:ii, alive, 1067 days 5809.5
                                  TCGA-RC-A7SK-01A 59 years, male, asian, stage:i, alive, 472 days 5795.0
                                  TCGA-DD-A11C-01A 69 years, male, white, stage:i, alive, 662 days 5775.2
                                  TCGA-EP-A3RK-01A 73 years, male, white, stage:iiia, alive, 363 days 5751.2
                                  TCGA-DD-AADV-01A 50 years, male, asian, stage:i, alive, 574 days 5724.3
                                  TCGA-ED-A459-01A 47 years, male, asian, stage:ii, alive, 910 days 5637.7
                                  TCGA-ES-A2HT-01A 54 years, male, black or african american, stage:i, dead, 438 days 5637.0
                                  TCGA-CC-A9FW-01A 68 years, male, asian, stage:iiia, alive, 248 days 5552.0
                                  TCGA-UB-A7MC-01A 59 years, male, white, stage:iiia, alive, 500 days 5536.0
                                  TCGA-BC-A8YO-01A 66 years, female, white, stage:iiic, alive, 562 days 5482.0
                                  TCGA-2Y-A9H7-01A 81 years, female, white, stage:i, alive, 1168 days 5459.4
                                  TCGA-LG-A6GG-01A 79 years, female, white, stage:ii, alive, 387 days 5406.7
                                  TCGA-DD-AACN-01A 32 years, male, asian, stage:i, alive, 1302 days 5404.4
                                  TCGA-CC-A7IJ-01A 56 years, male, asian, stage:ii, alive, 382 days 5391.7
                                  TCGA-CC-A8HU-01A 39 years, female, asian, stage:iiia, dead, 344 days 5382.3
                                  TCGA-DD-A39X-01A 78 years, female, white, stage:i, dead, 1694 days 5376.8
                                  TCGA-G3-A7M9-01A 70 years, male, white, stage:iiib, dead, 56 days 5362.7
                                  TCGA-BC-A10Y-01A 76 years, male, white, dead, 711 days 5331.1
                                  TCGA-CC-A1HT-01A 50 years, male, asian, stage:iiia, dead, 101 days 5285.7
                                  TCGA-ZP-A9CZ-01A 72 years, male, asian, alive, 706 days 5198.0
                                  TCGA-DD-A39Y-01A 67 years, male, asian, stage:i, dead, 171 days 5192.6
                                  TCGA-DD-AAW0-01A 54 years, male, asian, stage:i, alive, 2015 days 5160.9
                                  TCGA-UB-A7ME-01A 51 years, male, asian, stage:i, alive, 486 days 5158.3
                                  TCGA-G3-AAV6-01A 53 years, female, white, stage:iiia, dead, 65 days 5120.3
                                  TCGA-GJ-A9DB-01A 68 years, male, white, stage:i, dead, 67 days 5111.4
                                  TCGA-ED-A66X-01A 35 years, male, asian, stage:iiia, alive, 406 days 5085.8
                                  TCGA-FV-A2QR-01A male, white, stage:i, dead, 581 days 5047.3
                                  TCGA-XR-A8TE-01A 16 years, male, white, stage:iiia, alive, 925 days 5015.4
                                  TCGA-DD-AAC8-01A 72 years, male, asian, stage:i, dead, 16 days 4984.5
                                  TCGA-DD-A114-01A 42 years, male, black or african american, stage:ii, dead, 1149 days 4956.0
                                  TCGA-UB-A7MD-01A 67 years, male, black or african american, stage:i, dead, 52 days 4944.5
                                  TCGA-FV-A3I0-01A 76 years, female, white, stage:ii, alive, 848 days 4940.8
                                  TCGA-G3-A25Y-01A 52 years, female, asian, stage:i, dead, 452 days 4881.3
                                  TCGA-DD-A1EI-01A 46 years, male, asian, stage:i, alive, 183 days 4800.5
                                  TCGA-FV-A4ZQ-01A 52 years, male, white, stage:i, alive, 12 days 4744.2
                                  TCGA-DD-A39V-01A 77 years, male, white, stage:ii, dead, 643 days 4729.6
                                  TCGA-T1-A6J8-01A 68 years, male, white, alive, 23 days 4729.3
                                  TCGA-G3-A25X-01A 73 years, male, asian, stage:ii, alive, 1779 days 4701.6
                                  TCGA-FV-A3R2-01A 75 years, male, white, stage:i, dead, 194 days 4481.9
                                  TCGA-DD-AACU-01A 59 years, male, asian, stage:i, alive, 1567 days 4445.2
                                  TCGA-DD-AACK-01A 70 years, male, asian, stage:i, alive, 9 days 4418.8
                                  TCGA-UB-A7MA-01A 62 years, female, white, stage:ii, alive, 848 days 4315.9
                                  TCGA-ED-A66Y-01A 51 years, female, asian, stage:iiia, dead, 296 days 4282.9
                                  TCGA-CC-A3M9-01A 45 years, male, asian, stage:iiia, dead, 300 days 4258.9
                                  TCGA-DD-AAD1-01A 51 years, female, asian, stage:i, alive, 564 days 4248.8
                                  TCGA-GJ-A6C0-01A 75 years, female, white, stage:ii, dead, 31 days 4246.4
                                  TCGA-BC-A10W-01A 50 years, male, asian, dead, 91 days 4225.2
                                  TCGA-CC-A7II-01A 55 years, male, asian, stage:iiia, alive, 399 days 4205.3
                                  TCGA-FV-A2QQ-01A 80 years, male, white, stage:i, alive, 729 days 4040.1
                                  TCGA-CC-5263-01A 35 years, male, asian, stage:iiia, dead, 129 days 3930.1
                                  TCGA-YA-A8S7-01A 69 years, male, white, stage:iiia, dead, 412 days 3566.4
                                  TCGA-DD-A73C-01A 65 years, female, white, stage:iiia, alive, 701 days 3483.2
                                  TCGA-CC-5258-01A 48 years, male, asian, stage:ii, dead, 129 days 3352.6
                                  TCGA-RC-A6M6-01A 75 years, male, white, stage:ii, alive, 9 days 3351.6
                                  TCGA-ZP-A9D2-01A 51 years, male, white, dead, 765 days 3287.2
                                  TCGA-CC-5264-01A 71 years, male, asian, stage:iiia, dead, 102 days 3037.9
                                  TCGA-BC-4073-01B 73 years, male, white, stage:iiia, alive, 849 days 2793.9
                                  TCGA-FV-A3I1-01A female, white, stage:ii, dead, 247 days 2654.1
                                  TCGA-UB-A7MB-01A 24 years, male, white, stage:ii, alive, 601 days 2572.6
                                  TCGA-BC-A69H-01A 64 years, male, white, stage:ii, alive, 444 days 2510.6
                                  TCGA-ED-A5KG-01A 60 years, female, asian, stage:ii, alive, 854 days 2303.7
                                  TCGA-CC-5261-01A 44 years, male, asian, stage:ii, dead, 97 days 1829.9
                                  Show allShow less
                                  6715.09329.913320.31829.923161.605,00010,00015,00020,00025,00030,00035,000
                                  6715.09329.913320.31829.923161.605,00010,00015,00020,00025,00030,00035,000
                                  LIVER CANCER - Protein expressioni

                                  A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

                                  Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

                                   

                                  Antibody stainingi

                                  Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

                                  Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


                                  Antibody HPA051505

                                  Antibody HPA054758

                                  Antibody CAB016243
                                   Staining
                                    High
                                    Medium
                                    Low
                                    Not detected
                                   Intensity
                                    Strong
                                    Moderate
                                    Weak
                                    Negative
                                   Quantity
                                    >75%
                                    75%-25%
                                    <25%
                                    None
                                   Location
                                    Nuclear
                                    Cytoplasmic/membranous
                                    Cytoplasmic/membranous,nuclear
                                    None
                                  Click images for details

                                  Contact

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                                  The Human Protein Atlas project is funded
                                  by the Knut & Alice Wallenberg Foundation.


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