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MT-ND4
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                                  • MT-ND4
                                  PATHOLOGY LIVER CANCER Show tissue menu
                                  BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
                                  MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
                                  ANTIBODIES
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                                  Dictionary
                                  Liver cancer
                                  Human pathology
                                  Liver cancer
                                  LIVER CANCER - Interactive survival scatter ploti

                                  The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

                                  The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

                                  Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

                                  Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

                                  & Survival analysisi

                                  Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

                                  MT-ND4 is not prognostic in liver cancer


                                  Stage:


                                  0 1 2 3 4 5 6 7 8 910Time after diagnosis (years)0.05.0k10k15k20k25k30k35kExpression level (FPKM)Dead (n=130)Alive (n=235)7.5e+3Density dead8.0e+3Density alive0.78Density dead under cut off1.3Density dead over cut off0.00.20.40.60.81.0P score0.00.50.40.30.20.60.81.0Medain separation0.1P scoreDead median separationCut off
                                  0.00.10.20.30.40.50.60.70.80.91.0Survival probability 0 1 2 3 4 5 6 7 8 910Time (years)Low expression (n=75)High expression (n=290)
                                  Survival analysis
                                  Current cut offi

                                  Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

                                  :
                                  Best expression cut offi

                                  Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

                                  When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

                                  : 4649.44
                                  Median expressioni

                                  Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

                                  : 7777.28
                                  Median follow up timei

                                  Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

                                  : 1.63
                                  P scorei

                                  Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

                                  0.0025
                                  5-year survival highi

                                  5-year survival for patients with higher expression than the expression cutoff.

                                  For melanoma and glioma, 3-year survival is shown.

                                  52%
                                  5-year survival lowi

                                  5-year survival for patients with lower expression than the expression cutoff.

                                  For melanoma and glioma, 3-year survival is shown.

                                  30%
                                  TCGA RNA samplesi

                                  RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

                                  Average FPKM 8826.6
                                  Number of samples 365
                                  Samples
                                  Sample Description FPKM
                                  TCGA-MR-A8JO-01A 34 years, male, white, stage:i, alive, 330 days 36907.8
                                  TCGA-DD-A4NG-01A 77 years, male, white, stage:iiia, dead, 802 days 36288.5
                                  TCGA-DD-A3A2-01A 76 years, female, white, stage:i, dead, 2131 days 30283.5
                                  TCGA-WX-AA47-01A 33 years, female, white, stage:iiia, dead, 556 days 28235.8
                                  TCGA-NI-A4U2-01A 71 years, male, white, stage:iiia, dead, 1791 days 24112.9
                                  TCGA-5R-AA1D-01A 17 years, female, white, stage:iiia, alive, 449 days 22396.4
                                  TCGA-NI-A8LF-01A 74 years, male, white, stage:i, alive, 799 days 22349.5
                                  TCGA-DD-AADU-01A 60 years, male, asian, stage:ii, alive, 554 days 22326.0
                                  TCGA-DD-A4NI-01A 67 years, male, white, stage:ii, alive, 816 days 22266.0
                                  TCGA-WJ-A86L-01A 68 years, female, white, stage:i, alive, 345 days 21585.9
                                  TCGA-BC-A216-01A 62 years, female, white, stage:iiia, alive, 1351 days 21195.6
                                  TCGA-DD-A3A6-01A 72 years, female, white, stage:ii, dead, 3258 days 20491.9
                                  TCGA-CC-A8HT-01A 74 years, male, asian, stage:iiia, dead, 140 days 20477.4
                                  TCGA-DD-A1EK-01A 64 years, female, white, stage:ivb, dead, 558 days 20017.2
                                  TCGA-2Y-A9H2-01A 64 years, female, white, stage:i, alive, 1731 days 19719.8
                                  TCGA-ZP-A9D4-01A 64 years, female, white, alive, 395 days 19627.9
                                  TCGA-CC-A7IF-01A 59 years, male, asian, stage:iiia, dead, 649 days 19458.0
                                  TCGA-RC-A7SH-01A 42 years, male, asian, stage:ii, alive, 468 days 19197.1
                                  TCGA-DD-AAD6-01A 66 years, male, asian, stage:iiia, alive, 672 days 19113.0
                                  TCGA-DD-AACE-01A 62 years, male, asian, stage:i, alive, 2184 days 19056.2
                                  TCGA-BD-A3ER-01A 62 years, male, white, stage:ii, alive, 1115 days 17897.3
                                  TCGA-DD-A73A-01A 71 years, male, white, stage:i, alive, 728 days 17877.4
                                  TCGA-DD-A4NB-01A 25 years, male, white, stage:i, alive, 989 days 17492.2
                                  TCGA-WQ-A9G7-01A female, white, alive, 30 days 17131.6
                                  TCGA-CC-A8HV-01A 51 years, female, asian, stage:ii, dead, 279 days 17092.8
                                  TCGA-DD-AAEA-01A 65 years, male, asian, stage:i, alive, 575 days 16446.1
                                  TCGA-RC-A7SB-01A 53 years, male, asian, stage:ii, alive, 588 days 16362.8
                                  TCGA-EP-A3JL-01A 76 years, male, white, stage:i, alive, 303 days 16069.8
                                  TCGA-G3-A3CH-01A 53 years, male, asian, stage:iiia, alive, 780 days 15834.7
                                  TCGA-RC-A7SF-01A 66 years, male, asian, stage:i, alive, 579 days 15739.5
                                  TCGA-DD-AAE6-01A 59 years, female, asian, stage:i, alive, 141 days 15603.5
                                  TCGA-DD-AAD8-01A 73 years, female, asian, stage:i, alive, 1219 days 15374.6
                                  TCGA-BC-A10Z-01A 62 years, female, white, stage:i, dead, 34 days 15358.9
                                  TCGA-DD-AADA-01A 66 years, female, asian, stage:i, alive, 1233 days 15303.3
                                  TCGA-CC-A7IE-01A 57 years, male, asian, stage:iiia, dead, 217 days 15086.6
                                  TCGA-2Y-A9GU-01A 55 years, female, white, stage:i, alive, 1939 days 14823.8
                                  TCGA-PD-A5DF-01A 58 years, female, white, stage:iiib, dead, 639 days 14799.2
                                  TCGA-BC-A10R-01A 66 years, female, white, dead, 308 days 14630.8
                                  TCGA-CC-A3MC-01A 54 years, male, asian, stage:iiia, alive, 363 days 14445.2
                                  TCGA-KR-A7K0-01A 65 years, male, white, stage:i, dead, 65 days 14426.4
                                  TCGA-DD-A3A8-01A 75 years, male, white, stage:ii, dead, 11 days 14421.4
                                  TCGA-FV-A3R3-01A 38 years, female, white, stage:i, dead, 366 days 14260.8
                                  TCGA-LG-A9QC-01A 48 years, male, white, stage:i, alive, 425 days 14163.1
                                  TCGA-BC-A10Q-01A 72 years, female, white, dead, 1135 days 14127.9
                                  TCGA-DD-A118-01A 77 years, female, white, stage:ii, alive, 3437 days 14102.0
                                  TCGA-DD-AAE9-01A 69 years, male, asian, stage:i, alive, 722 days 14027.3
                                  TCGA-DD-AACT-01A 69 years, female, asian, stage:i, alive, 1562 days 13968.3
                                  TCGA-K7-A5RG-01A 66 years, male, black or african american, stage:i, alive, 519 days 13896.1
                                  TCGA-DD-A73D-01A 68 years, female, white, stage:ii, alive, 693 days 13858.0
                                  TCGA-DD-A4NL-01A 46 years, male, white, stage:i, alive, 1711 days 13728.1
                                  TCGA-G3-AAV1-01A 51 years, male, asian, stage:iiic, dead, 359 days 13712.2
                                  TCGA-KR-A7K8-01A 57 years, male, stage:i, alive, 906 days 13537.0
                                  TCGA-DD-A1EB-01A 72 years, female, stage:i, alive, 2017 days 13524.7
                                  TCGA-G3-A5SK-01A 58 years, male, white, stage:i, alive, 744 days 13511.0
                                  TCGA-DD-AAED-01A 51 years, male, asian, stage:i, alive, 763 days 13507.1
                                  TCGA-EP-A26S-01A 70 years, male, white, stage:i, alive, 608 days 13481.5
                                  TCGA-G3-A7M8-01A 31 years, male, asian, stage:i, alive, 430 days 13353.4
                                  TCGA-ZS-A9CF-01A 64 years, male, white, stage:ii, alive, 2412 days 13302.8
                                  TCGA-DD-A4NE-01A 75 years, female, white, stage:iiia, dead, 660 days 13125.6
                                  TCGA-HP-A5MZ-01A 62 years, male, stage:i, dead, 91 days 13089.4
                                  TCGA-DD-A116-01A 68 years, male, asian, stage:iiia, dead, 1622 days 12980.2
                                  TCGA-XR-A8TD-01A 49 years, female, white, stage:iiib, alive, 1030 days 12883.9
                                  TCGA-DD-AAEB-01A 60 years, male, asian, stage:i, alive, 478 days 12851.9
                                  TCGA-DD-AAEH-01A 73 years, male, asian, stage:i, alive, 784 days 12836.7
                                  TCGA-BC-A3KF-01A 66 years, female, white, stage:i, alive, 8 days 12796.1
                                  TCGA-G3-A5SJ-01A 59 years, male, white, stage:i, alive, 698 days 12764.8
                                  TCGA-CC-A7IL-01A 61 years, male, asian, stage:iiia, dead, 278 days 12463.5
                                  TCGA-DD-AADL-01A 58 years, male, asian, stage:i, alive, 636 days 12393.7
                                  TCGA-RC-A6M5-01A 20 years, female, white, stage:iva, alive, 15 days 12269.0
                                  TCGA-DD-AAW2-01A 69 years, male, asian, stage:i, alive, 1855 days 12255.6
                                  TCGA-DD-AACX-01A 66 years, male, asian, stage:ii, alive, 170 days 12145.7
                                  TCGA-DD-A4NS-01A 62 years, female, white, stage:i, dead, 2456 days 12085.6
                                  TCGA-ZS-A9CG-01A 55 years, male, white, stage:ii, alive, 341 days 12059.5
                                  TCGA-DD-A4NJ-01A 54 years, female, white, stage:ii, alive, 928 days 11997.4
                                  TCGA-ED-A4XI-01A 58 years, male, asian, stage:ii, alive, 819 days 11927.3
                                  TCGA-WX-AA44-01A 64 years, female, white, stage:i, alive, 615 days 11904.8
                                  TCGA-MI-A75C-01A 64 years, male, white, stage:i, alive, 291 days 11902.7
                                  TCGA-XR-A8TF-01A 74 years, male, white, stage:i, dead, 693 days 11817.9
                                  TCGA-DD-A1EE-01A 73 years, male, white, stage:iiia, dead, 349 days 11810.6
                                  TCGA-2Y-A9GW-01A 64 years, male, white, stage:i, dead, 1271 days 11773.1
                                  TCGA-DD-A73B-01A 72 years, female, white, stage:i, dead, 283 days 11722.2
                                  TCGA-UB-AA0V-01A 69 years, female, white, stage:i, alive, 314 days 11688.0
                                  TCGA-WQ-AB4B-01A 62 years, male, white, stage:ii, alive, 395 days 11683.0
                                  TCGA-K7-AAU7-01A 61 years, male, white, stage:ii, alive, 359 days 11623.7
                                  TCGA-DD-A11B-01A 73 years, male, white, stage:i, dead, 14 days 11520.1
                                  TCGA-2Y-A9H6-01A 68 years, female, white, stage:i, alive, 357 days 11510.0
                                  TCGA-BC-A3KG-01A 68 years, female, white, stage:ii, alive, 680 days 11508.4
                                  TCGA-EP-A2KC-01A 62 years, male, black or african american, stage:i, dead, 19 days 11497.1
                                  TCGA-G3-A25Z-01A 58 years, male, asian, stage:i, alive, 655 days 11479.6
                                  TCGA-CC-A3MA-01A 61 years, male, asian, stage:iiia, dead, 303 days 11463.1
                                  TCGA-DD-AACA-01A 65 years, male, asian, stage:i, alive, 2301 days 11419.2
                                  TCGA-DD-A1EC-01A 20 years, female, white, stage:i, alive, 602 days 11392.4
                                  TCGA-G3-A3CI-01A 71 years, male, white, stage:i, alive, 180 days 11325.4
                                  TCGA-DD-AAVW-01A 35 years, male, asian, stage:i, alive, 2317 days 11266.2
                                  TCGA-DD-AACJ-01A 75 years, male, asian, stage:ii, alive, 2102 days 11231.5
                                  TCGA-DD-AAW1-01A 55 years, male, asian, stage:iiia, alive, 1989 days 11221.0
                                  TCGA-BD-A2L6-01A 69 years, male, white, alive, 1363 days 11071.3
                                  TCGA-DD-A11C-01A 69 years, male, white, stage:i, alive, 662 days 11030.1
                                  TCGA-DD-A4NK-01A 80 years, female, white, stage:iiia, dead, 1210 days 11021.0
                                  TCGA-XR-A8TC-01A 43 years, female, white, stage:i, alive, 1339 days 11000.7
                                  TCGA-DD-A3A4-01A 37 years, male, white, stage:iiia, dead, 612 days 10997.0
                                  TCGA-BC-A10X-01A 52 years, female, white, stage:iiia, dead, 770 days 10973.7
                                  TCGA-DD-AADG-01A 70 years, male, asian, stage:iiia, alive, 1145 days 10965.5
                                  TCGA-DD-AAD0-01A 73 years, female, asian, stage:i, alive, 137 days 10927.5
                                  TCGA-BC-A10T-01A 76 years, male, white, dead, 837 days 10851.5
                                  TCGA-QA-A7B7-01A 48 years, male, black or african american, stage:ii, alive, 94 days 10792.4
                                  TCGA-DD-AADR-01A 58 years, male, asian, stage:i, alive, 2028 days 10758.8
                                  TCGA-DD-AAE1-01A 52 years, male, asian, stage:i, alive, 552 days 10746.3
                                  TCGA-DD-AADF-01A 64 years, female, asian, stage:i, dead, 115 days 10738.8
                                  TCGA-DD-AAW3-01A 69 years, male, asian, stage:i, alive, 1633 days 10639.1
                                  TCGA-CC-A5UC-01A 63 years, male, asian, stage:iiia, dead, 347 days 10546.8
                                  TCGA-DD-A4ND-01A 56 years, female, white, stage:i, alive, 2746 days 10545.4
                                  TCGA-BC-A10U-01A 69 years, male, white, dead, 837 days 10508.0
                                  TCGA-RC-A7S9-01A 47 years, female, asian, stage:i, alive, 640 days 10504.0
                                  TCGA-CC-A9FS-01A 55 years, male, asian, stage:ii, alive, 211 days 10474.8
                                  TCGA-WX-AA46-01A 62 years, male, white, stage:ii, alive, 756 days 10431.6
                                  TCGA-ED-A7PX-01A 48 years, female, asian, stage:ii, alive, 6 days 10365.1
                                  TCGA-DD-AADK-01A 68 years, female, asian, stage:ii, alive, 1049 days 10363.3
                                  TCGA-DD-A4NF-01A 72 years, male, white, stage:i, alive, 942 days 10320.6
                                  TCGA-G3-A5SL-01A 70 years, male, white, stage:ii, alive, 621 days 10263.9
                                  TCGA-ED-A7PZ-01A 61 years, male, asian, stage:ii, alive, 6 days 10199.4
                                  TCGA-DD-A4NA-01A 67 years, female, white, stage:iiic, alive, 1008 days 10183.2
                                  TCGA-UB-AA0U-01A 60 years, male, white, stage:ii, alive, 327 days 10149.0
                                  TCGA-2Y-A9H8-01A 85 years, female, white, dead, 633 days 10125.5
                                  TCGA-DD-AAE3-01A 50 years, male, asian, stage:i, alive, 566 days 10054.7
                                  TCGA-DD-AA3A-01A 81 years, female, white, stage:i, dead, 410 days 9987.5
                                  TCGA-DD-AADD-01A 51 years, male, asian, stage:i, alive, 1231 days 9945.2
                                  TCGA-4R-AA8I-01A 66 years, male, white, stage:ii, dead, 262 days 9909.5
                                  TCGA-CC-A8HS-01A 18 years, male, asian, stage:iiic, dead, 300 days 9871.3
                                  TCGA-MR-A520-01A 58 years, male, white, stage:i, alive, 229 days 9846.8
                                  TCGA-DD-A4NH-01A 65 years, female, white, stage:iiib, alive, 917 days 9770.1
                                  TCGA-ED-A7PY-01A 20 years, female, asian, stage:ii, alive, 390 days 9754.5
                                  TCGA-BC-4072-01B 74 years, female, white, stage:iiia, dead, 1490 days 9707.5
                                  TCGA-G3-A5SM-01A 58 years, male, white, stage:ii, alive, 520 days 9694.7
                                  TCGA-2Y-A9GX-01A 68 years, male, white, stage:i, alive, 2442 days 9688.5
                                  TCGA-RC-A7SK-01A 59 years, male, asian, stage:i, alive, 472 days 9667.9
                                  TCGA-DD-A4NQ-01A 60 years, male, white, stage:ii, dead, 373 days 9644.1
                                  TCGA-MI-A75H-01A 77 years, male, white, alive, 747 days 9620.2
                                  TCGA-LG-A9QD-01A 68 years, male, white, stage:iiia, alive, 366 days 9566.9
                                  TCGA-2Y-A9GV-01A 54 years, female, white, stage:i, dead, 2532 days 9513.1
                                  TCGA-RC-A6M4-01A 74 years, female, white, stage:iiia, alive, 22 days 9412.5
                                  TCGA-CC-A5UD-01A 45 years, male, asian, stage:iiia, dead, 304 days 9330.1
                                  TCGA-BC-A112-01A 80 years, male, white, dead, 153 days 9324.9
                                  TCGA-BC-A110-01A 51 years, female, black or african american, dead, 2116 days 9287.5
                                  TCGA-ED-A82E-01A 60 years, female, asian, stage:iiia, alive, 408 days 9272.6
                                  TCGA-CC-A7IH-01A 58 years, male, asian, stage:iiia, alive, 365 days 9243.0
                                  TCGA-G3-A6UC-01A 65 years, male, white, stage:iiib, alive, 671 days 9156.7
                                  TCGA-DD-A11A-01A 67 years, male, black or african american, stage:i, alive, 79 days 9100.1
                                  TCGA-G3-A7M7-01A 65 years, male, white, stage:i, alive, 361 days 9092.4
                                  TCGA-RG-A7D4-01A 69 years, male, black or african american, stage:ii, alive, 1098 days 9024.9
                                  TCGA-DD-A73F-01A 77 years, female, white, stage:i, alive, 1085 days 8991.5
                                  TCGA-DD-AACQ-01A 50 years, male, asian, stage:ii, dead, 432 days 8900.8
                                  TCGA-DD-A115-01A 53 years, male, white, stage:iiia, dead, 2542 days 8868.3
                                  TCGA-G3-A3CJ-01A 52 years, male, american indian or alaska native, stage:ii, alive, 594 days 8844.1
                                  TCGA-DD-A1ED-01A 68 years, male, white, stage:i, alive, 2301 days 8840.7
                                  TCGA-DD-AAEK-01A 51 years, male, asian, stage:ii, alive, 1067 days 8730.7
                                  TCGA-DD-AAVR-01A 44 years, male, asian, stage:i, alive, 2513 days 8658.9
                                  TCGA-DD-A3A7-01A 67 years, male, stage:iiib, dead, 419 days 8641.4
                                  TCGA-DD-A1EF-01A 57 years, female, white, stage:i, dead, 394 days 8620.3
                                  TCGA-DD-A1EA-01A 68 years, male, asian, stage:ii, alive, 2415 days 8589.7
                                  TCGA-ED-A7XP-01A 53 years, female, asian, stage:ii, alive, 400 days 8569.2
                                  TCGA-2Y-A9H0-01A 49 years, male, white, stage:iiia, alive, 3675 days 8563.9
                                  TCGA-2Y-A9GZ-01A 82 years, female, white, stage:ii, dead, 848 days 8403.9
                                  TCGA-MI-A75E-01A 61 years, male, white, stage:iiic, alive, 507 days 8314.1
                                  TCGA-DD-AAEG-01A 59 years, female, asian, stage:i, alive, 719 days 8270.5
                                  TCGA-2Y-A9H5-01A 59 years, female, white, stage:i, dead, 555 days 8245.3
                                  TCGA-DD-A4NR-01A 85 years, female, white, stage:i, dead, 9 days 8205.9
                                  TCGA-KR-A7K2-01A 64 years, male, white, stage:i, alive, 829 days 8173.9
                                  TCGA-DD-AADC-01A 53 years, male, asian, stage:i, dead, 425 days 8156.4
                                  TCGA-2Y-A9GT-01A 51 years, male, white, stage:i, dead, 1624 days 8141.5
                                  TCGA-ED-A97K-01A 54 years, male, asian, stage:iiia, alive, 6 days 8136.3
                                  TCGA-ZP-A9D1-01A 56 years, female, white, alive, 21 days 8077.0
                                  TCGA-DD-A4NP-01A 32 years, male, white, stage:i, alive, 3308 days 8045.5
                                  TCGA-ZP-A9D0-01A 67 years, female, black or african american, alive, 1091 days 8044.9
                                  TCGA-DD-A39W-01A 29 years, female, white, stage:iii, dead, 827 days 8036.2
                                  TCGA-DD-AACZ-01A 63 years, female, asian, stage:i, dead, 171 days 8006.9
                                  TCGA-DD-A119-01A 40 years, male, asian, stage:iv, dead, 223 days 7982.0
                                  TCGA-DD-AAEI-01A 72 years, male, asian, stage:i, alive, 1531 days 7965.8
                                  TCGA-ED-A627-01A 74 years, male, white, stage:i, alive, 423 days 7913.3
                                  TCGA-ZS-A9CD-01A 73 years, male, white, stage:ii, dead, 1386 days 7904.7
                                  TCGA-5R-AAAM-01A 65 years, female, white, stage:ii, dead, 46 days 7899.8
                                  TCGA-DD-AADB-01A 51 years, male, asian, stage:i, alive, 1242 days 7779.9
                                  TCGA-CC-A3MB-01A 36 years, male, asian, stage:iiia, dead, 315 days 7777.3
                                  TCGA-2Y-A9H9-01A 70 years, male, white, stage:i, alive, 697 days 7775.0
                                  TCGA-G3-A5SI-01A 44 years, male, asian, stage:ii, dead, 768 days 7672.2
                                  TCGA-2Y-A9H4-01A 68 years, male, black or african american, stage:i, alive, 1452 days 7659.3
                                  TCGA-DD-AAD2-01A 66 years, male, asian, stage:i, alive, 658 days 7650.5
                                  TCGA-DD-AAVP-01A 48 years, male, asian, stage:i, alive, 2752 days 7632.9
                                  TCGA-DD-AACS-01A 39 years, male, asian, stage:i, alive, 1804 days 7626.4
                                  TCGA-DD-AAE2-01A 51 years, male, asian, stage:i, alive, 638 days 7598.7
                                  TCGA-UB-A7MD-01A 67 years, male, black or african american, stage:i, dead, 52 days 7580.5
                                  TCGA-DD-AAD5-01A 54 years, male, asian, stage:i, alive, 1345 days 7556.2
                                  TCGA-5C-A9VG-01A 58 years, male, white, stage:ii, alive, 328 days 7530.8
                                  TCGA-DD-AAC9-01A 51 years, male, asian, stage:i, alive, 347 days 7509.5
                                  TCGA-2Y-A9HA-01A 70 years, male, white, stage:ii, dead, 36 days 7483.3
                                  TCGA-DD-AACV-01A 53 years, male, asian, stage:i, alive, 1531 days 7482.4
                                  TCGA-ED-A459-01A 47 years, male, asian, stage:ii, alive, 910 days 7474.1
                                  TCGA-DD-A4NV-01A 61 years, male, white, stage:iiia, alive, 2398 days 7451.0
                                  TCGA-5C-A9VH-01A 70 years, male, white, stage:i, alive, 322 days 7444.1
                                  TCGA-EP-A2KB-01A 46 years, female, white, stage:i, dead, 596 days 7432.7
                                  TCGA-G3-A25T-01A 45 years, female, white, stage:iiia, alive, 1553 days 7426.0
                                  TCGA-DD-AAVS-01A 56 years, male, asian, stage:i, alive, 1823 days 7401.9
                                  TCGA-G3-A7M5-01A 76 years, male, asian, stage:i, alive, 447 days 7381.8
                                  TCGA-GJ-A3OU-01A 59 years, male, white, stage:i, alive, 879 days 7269.9
                                  TCGA-ZP-A9CY-01A 66 years, female, white, alive, 782 days 7269.6
                                  TCGA-BD-A3EP-01A 76 years, female, black or african american, stage:i, alive, 409 days 7213.4
                                  TCGA-DD-AADW-01A 48 years, male, asian, stage:i, alive, 587 days 7200.2
                                  TCGA-CC-A7IK-01A 59 years, male, asian, stage:iiia, dead, 262 days 7158.9
                                  TCGA-GJ-A6C0-01A 75 years, female, white, stage:ii, dead, 31 days 7104.7
                                  TCGA-DD-AAEE-01A 55 years, male, asian, stage:i, alive, 810 days 7038.7
                                  TCGA-BC-A69I-01A 69 years, male, white, stage:i, alive, 387 days 6894.4
                                  TCGA-DD-AAVX-01A 38 years, male, asian, stage:ii, alive, 1570 days 6877.3
                                  TCGA-G3-A25U-01A 63 years, female, asian, stage:i, alive, 1636 days 6871.5
                                  TCGA-G3-A25S-01A 64 years, male, white, stage:i, dead, 416 days 6866.2
                                  TCGA-DD-A3A5-01A 66 years, female, white, stage:iii, dead, 3125 days 6839.3
                                  TCGA-BC-A8YO-01A 66 years, female, white, stage:iiic, alive, 562 days 6818.6
                                  TCGA-DD-A3A3-01A 45 years, male, asian, stage:i, dead, 535 days 6808.2
                                  TCGA-XR-A8TE-01A 16 years, male, white, stage:iiia, alive, 925 days 6794.0
                                  TCGA-DD-A1EG-01A 77 years, male, white, stage:i, dead, 1372 days 6651.3
                                  TCGA-DD-A1EL-01A 23 years, male, black or african american, stage:ii, dead, 415 days 6623.4
                                  TCGA-G3-A25V-01A 68 years, male, white, stage:i, alive, 860 days 6483.3
                                  TCGA-5C-AAPD-01A 61 years, male, asian, stage:ii, alive, 20 days 6420.5
                                  TCGA-DD-AACL-01A 66 years, female, asian, stage:i, dead, 107 days 6419.3
                                  TCGA-CC-5259-01A 60 years, female, asian, stage:iiic, alive, 250 days 6379.8
                                  TCGA-BC-A10Y-01A 76 years, male, white, dead, 711 days 6326.7
                                  TCGA-FV-A23B-01A 70 years, female, white, stage:ii, dead, 1852 days 6322.0
                                  TCGA-DD-A1EH-01A 23 years, male, white, stage:iii, alive, 1495 days 6311.0
                                  TCGA-K7-A5RF-01A 64 years, male, white, stage:i, alive, 631 days 6299.1
                                  TCGA-DD-AAVY-01A 56 years, male, asian, stage:iiia, alive, 1970 days 6297.1
                                  TCGA-G3-AAV4-01A 83 years, female, white, stage:i, dead, 27 days 6286.0
                                  TCGA-ED-A8O6-01A 50 years, female, asian, stage:iiia, dead, 56 days 6268.2
                                  TCGA-DD-AAVZ-01A 38 years, male, asian, stage:i, alive, 1900 days 6221.1
                                  TCGA-DD-AACW-01A 43 years, male, asian, stage:i, alive, 1424 days 6196.9
                                  TCGA-ED-A66X-01A 35 years, male, asian, stage:iiia, alive, 406 days 6150.6
                                  TCGA-FV-A3I0-01A 76 years, female, white, stage:ii, alive, 848 days 6146.9
                                  TCGA-2Y-A9GS-01A 58 years, male, white, dead, 724 days 6139.6
                                  TCGA-DD-AAVQ-01A 38 years, male, asian, stage:i, alive, 2728 days 6131.1
                                  TCGA-BC-A10S-01A 81 years, male, white, dead, 1423 days 6127.4
                                  TCGA-G3-A3CK-01A 61 years, male, asian, stage:i, alive, 585 days 6122.6
                                  TCGA-DD-AAW0-01A 54 years, male, asian, stage:i, alive, 2015 days 6120.3
                                  TCGA-CC-A8HU-01A 39 years, female, asian, stage:iiia, dead, 344 days 6097.1
                                  TCGA-EP-A12J-01A 63 years, male, black or african american, stage:i, alive, 570 days 6039.4
                                  TCGA-UB-A7MC-01A 59 years, male, white, stage:iiia, alive, 500 days 5976.4
                                  TCGA-O8-A75V-01A 54 years, male, stage:i, alive, 538 days 5922.0
                                  TCGA-DD-A4NO-01A 66 years, male, white, stage:i, alive, 2245 days 5899.9
                                  TCGA-DD-A11D-01A 57 years, female, white, stage:i, dead, 1560 days 5895.3
                                  TCGA-G3-AAV5-01A 67 years, male, white, stage:ii, alive, 354 days 5885.3
                                  TCGA-BC-A5W4-01A 69 years, male, white, stage:iiia, dead, 547 days 5875.5
                                  TCGA-DD-A114-01A 42 years, male, black or african american, stage:ii, dead, 1149 days 5784.7
                                  TCGA-DD-AADQ-01A 59 years, male, asian, stage:ii, alive, 436 days 5750.7
                                  TCGA-ED-A7XO-01A 29 years, male, asian, stage:iiia, alive, 427 days 5713.3
                                  TCGA-EP-A3RK-01A 73 years, male, white, stage:iiia, alive, 363 days 5694.5
                                  TCGA-DD-AACP-01A 65 years, male, asian, stage:i, alive, 415 days 5689.0
                                  TCGA-FV-A496-01A 84 years, female, white, stage:i, alive, 10 days 5642.2
                                  TCGA-DD-A39Z-01A 43 years, female, stage:ii, dead, 601 days 5637.3
                                  TCGA-DD-AAVV-01A 56 years, male, asian, stage:ii, alive, 2455 days 5628.4
                                  TCGA-DD-AAD1-01A 51 years, female, asian, stage:i, alive, 564 days 5607.8
                                  TCGA-DD-AACF-01A 68 years, male, asian, stage:i, dead, 365 days 5599.3
                                  TCGA-XR-A8TG-01A 59 years, male, white, stage:i, alive, 898 days 5559.4
                                  TCGA-G3-A7M9-01A 70 years, male, white, stage:iiib, dead, 56 days 5512.9
                                  TCGA-DD-A73E-01A 66 years, male, white, stage:i, alive, 44 days 5480.3
                                  TCGA-ZP-A9CV-01A 59 years, male, white, dead, 1088 days 5466.9
                                  TCGA-ED-A8O5-01A 59 years, female, asian, stage:iiia, alive, 406 days 5456.1
                                  TCGA-2Y-A9GY-01A 64 years, female, white, stage:ii, dead, 757 days 5407.7
                                  TCGA-DD-AADV-01A 50 years, male, asian, stage:i, alive, 574 days 5404.8
                                  TCGA-G3-AAV2-01A 50 years, male, white, stage:i, alive, 372 days 5326.0
                                  TCGA-G3-AAV3-01A 58 years, female, white, stage:ii, alive, 412 days 5228.8
                                  TCGA-DD-AACD-01A 48 years, male, asian, stage:i, dead, 381 days 5212.3
                                  TCGA-2Y-A9HB-01A 66 years, male, stage:i, alive, 260 days 5180.1
                                  TCGA-BW-A5NO-01A 50 years, male, black or african american, stage:iiia, alive, 20 days 5131.4
                                  TCGA-DD-AAE4-01A 49 years, female, asian, stage:i, alive, 608 days 5097.0
                                  TCGA-DD-AAD3-01A 43 years, male, asian, stage:i, alive, 1295 days 5057.2
                                  TCGA-DD-A113-01A 55 years, female, white, stage:ii, alive, 2425 days 5050.1
                                  TCGA-CC-5263-01A 35 years, male, asian, stage:iiia, dead, 129 days 5038.3
                                  TCGA-5R-AA1C-01A 57 years, male, white, stage:ii, alive, 520 days 5035.9
                                  TCGA-DD-A1EJ-01A 71 years, female, white, stage:iiic, dead, 1005 days 5023.0
                                  TCGA-DD-AAE0-01A 45 years, female, asian, stage:iiia, alive, 555 days 4979.9
                                  TCGA-DD-A3A9-01A 64 years, female, white, stage:ivb, dead, 931 days 4969.4
                                  TCGA-DD-A1EI-01A 46 years, male, asian, stage:i, alive, 183 days 4936.6
                                  TCGA-G3-A3CG-01A 80 years, male, white, stage:i, alive, 673 days 4913.6
                                  TCGA-DD-AADP-01A 45 years, male, asian, stage:i, alive, 458 days 4896.1
                                  TCGA-CC-A9FW-01A 68 years, male, asian, stage:iiia, alive, 248 days 4872.4
                                  TCGA-DD-AADY-01A 55 years, female, asian, stage:i, alive, 555 days 4870.3
                                  TCGA-DD-AACU-01A 59 years, male, asian, stage:i, alive, 1567 days 4860.4
                                  TCGA-DD-AACY-01A 61 years, male, asian, stage:i, alive, 1450 days 4848.5
                                  TCGA-ZS-A9CE-01A 79 years, female, white, stage:ii, alive, 1241 days 4839.5
                                  TCGA-FV-A2QR-01A male, white, stage:i, dead, 581 days 4745.1
                                  TCGA-2Y-A9H7-01A 81 years, female, white, stage:i, alive, 1168 days 4726.5
                                  TCGA-G3-AAV0-01A 58 years, male, asian, stage:i, alive, 476 days 4684.3
                                  TCGA-G3-AAV7-01A 38 years, male, asian, stage:ii, alive, 361 days 4662.8
                                  TCGA-CC-A7IG-01A 47 years, male, asian, stage:ii, dead, 299 days 4636.0
                                  TCGA-CC-A1HT-01A 50 years, male, asian, stage:iiia, dead, 101 days 4604.0
                                  TCGA-LG-A6GG-01A 79 years, female, white, stage:ii, alive, 387 days 4601.2
                                  TCGA-2Y-A9H3-01A 45 years, male, white, stage:ii, alive, 1516 days 4564.8
                                  TCGA-DD-AACC-01A 61 years, male, asian, stage:i, dead, 1685 days 4537.8
                                  TCGA-UB-A7MF-01A 57 years, male, white, stage:iiia, dead, 214 days 4489.6
                                  TCGA-3K-AAZ8-01A 65 years, male, black or african american, stage:iiib, alive, 396 days 4433.2
                                  TCGA-DD-AADJ-01A 70 years, female, asian, stage:i, alive, 1066 days 4409.0
                                  TCGA-DD-AADS-01A 63 years, male, asian, stage:i, alive, 474 days 4399.5
                                  TCGA-DD-AACB-01A 74 years, female, asian, stage:i, alive, 2324 days 4323.2
                                  TCGA-G3-A25Y-01A 52 years, female, asian, stage:i, dead, 452 days 4321.1
                                  TCGA-CC-5262-01A 67 years, male, asian, stage:iiic, dead, 103 days 4306.1
                                  TCGA-DD-AAC8-01A 72 years, male, asian, stage:i, dead, 16 days 4288.6
                                  TCGA-MI-A75G-01A 63 years, male, white, stage:ii, alive, 698 days 4275.0
                                  TCGA-RC-A6M6-01A 75 years, male, white, stage:ii, alive, 9 days 4257.5
                                  TCGA-KR-A7K7-01A 61 years, female, white, stage:ii, alive, 951 days 4247.6
                                  TCGA-ZP-A9CZ-01A 72 years, male, asian, alive, 706 days 4209.1
                                  TCGA-K7-A6G5-01A 66 years, male, white, stage:i, alive, 512 days 4207.5
                                  TCGA-DD-A4NN-01A 56 years, female, white, stage:i, dead, 899 days 4181.6
                                  TCGA-DD-AAE7-01A 72 years, male, asian, stage:i, alive, 644 days 4151.8
                                  TCGA-CC-5260-01A 61 years, female, asian, stage:iiic, dead, 87 days 4140.3
                                  TCGA-UB-A7ME-01A 51 years, male, asian, stage:i, alive, 486 days 4128.4
                                  TCGA-G3-A7M6-01A 60 years, female, white, stage:i, alive, 632 days 4121.2
                                  TCGA-G3-AAUZ-01A 48 years, male, stage:i, alive, 480 days 4037.9
                                  TCGA-CC-A5UE-01A 48 years, male, asian, stage:iiib, dead, 272 days 4024.0
                                  TCGA-DD-AACO-01A 40 years, male, asian, stage:i, alive, 1876 days 4006.1
                                  TCGA-DD-AACN-01A 32 years, male, asian, stage:i, alive, 1302 days 4001.1
                                  TCGA-MI-A75I-01A 61 years, male, black or african american, alive, 630 days 3989.8
                                  TCGA-2Y-A9H1-01A 58 years, male, white, stage:i, dead, 1229 days 3969.6
                                  TCGA-DD-AAVU-01A 46 years, male, asian, stage:ii, alive, 2202 days 3952.7
                                  TCGA-HP-A5N0-01A 88 years, female, dead, 1147 days 3936.8
                                  TCGA-DD-AACH-01A 69 years, male, asian, stage:ii, dead, 195 days 3839.3
                                  TCGA-ED-A66Y-01A 51 years, female, asian, stage:iiia, dead, 296 days 3802.9
                                  TCGA-EP-A2KA-01A 52 years, female, white, stage:iiia, dead, 627 days 3757.9
                                  TCGA-CC-A3M9-01A 45 years, male, asian, stage:iiia, dead, 300 days 3723.1
                                  TCGA-DD-AACK-01A 70 years, male, asian, stage:i, alive, 9 days 3635.5
                                  TCGA-FV-A3R2-01A 75 years, male, white, stage:i, dead, 194 days 3603.3
                                  TCGA-FV-A3I1-01A female, white, stage:ii, dead, 247 days 3587.7
                                  TCGA-YA-A8S7-01A 69 years, male, white, stage:iiia, dead, 412 days 3561.6
                                  TCGA-T1-A6J8-01A 68 years, male, white, alive, 23 days 3491.6
                                  TCGA-DD-AADM-01A 58 years, male, asian, stage:ii, dead, 12 days 3436.8
                                  TCGA-CC-5258-01A 48 years, male, asian, stage:ii, dead, 129 days 3412.4
                                  TCGA-GJ-A9DB-01A 68 years, male, white, stage:i, dead, 67 days 3373.5
                                  TCGA-DD-A73C-01A 65 years, female, white, stage:iiia, alive, 701 days 3340.4
                                  TCGA-BC-A217-01A 75 years, female, white, stage:ii, dead, 1397 days 3328.6
                                  TCGA-FV-A2QQ-01A 80 years, male, white, stage:i, alive, 729 days 3304.0
                                  TCGA-DD-AACI-01A 69 years, male, asian, stage:ii, alive, 1618 days 3255.5
                                  TCGA-ZP-A9D2-01A 51 years, male, white, dead, 765 days 3246.9
                                  TCGA-CC-A7IJ-01A 56 years, male, asian, stage:ii, alive, 382 days 3099.9
                                  TCGA-DD-A3A1-01A 65 years, male, stage:iiia, dead, 233 days 3074.7
                                  TCGA-BC-A10W-01A 50 years, male, asian, dead, 91 days 3012.2
                                  TCGA-DD-AACG-01A 52 years, male, asian, stage:ii, dead, 469 days 2884.8
                                  TCGA-DD-A73G-01A 73 years, female, white, stage:i, alive, 3478 days 2810.9
                                  TCGA-DD-AADI-01A 43 years, female, asian, stage:i, alive, 1085 days 2795.2
                                  TCGA-FV-A495-01A 51 years, female, white, stage:ii, alive, 1 days 2727.0
                                  TCGA-UB-A7MA-01A 62 years, female, white, stage:ii, alive, 848 days 2722.1
                                  TCGA-CC-5264-01A 71 years, male, asian, stage:iiia, dead, 102 days 2669.0
                                  TCGA-DD-AADN-01A 59 years, male, asian, stage:i, alive, 898 days 2558.0
                                  TCGA-ES-A2HS-01A 80 years, male, white, stage:i, dead, 688 days 2557.3
                                  TCGA-FV-A4ZQ-01A 52 years, male, white, stage:i, alive, 12 days 2478.1
                                  TCGA-UB-A7MB-01A 24 years, male, white, stage:ii, alive, 601 days 2457.9
                                  TCGA-CC-A7II-01A 55 years, male, asian, stage:iiia, alive, 399 days 2444.6
                                  TCGA-DD-A39X-01A 78 years, female, white, stage:i, dead, 1694 days 2344.9
                                  TCGA-CC-5261-01A 44 years, male, asian, stage:ii, dead, 97 days 2286.3
                                  TCGA-DD-A39Y-01A 67 years, male, asian, stage:i, dead, 171 days 2285.0
                                  TCGA-ES-A2HT-01A 54 years, male, black or african american, stage:i, dead, 438 days 2057.6
                                  TCGA-BC-4073-01B 73 years, male, white, stage:iiia, alive, 849 days 1960.8
                                  TCGA-G3-AAV6-01A 53 years, female, white, stage:iiia, dead, 65 days 1914.0
                                  TCGA-ED-A5KG-01A 60 years, female, asian, stage:ii, alive, 854 days 1810.3
                                  TCGA-CC-A123-01A 24 years, female, asian, stage:iiia, alive, 219 days 1741.9
                                  TCGA-DD-A39V-01A 77 years, male, white, stage:ii, dead, 643 days 1688.9
                                  TCGA-DD-AADO-01A 55 years, male, asian, stage:i, alive, 453 days 1606.0
                                  TCGA-FV-A4ZP-01A 78 years, male, white, stage:iiia, dead, 2486 days 1562.4
                                  TCGA-G3-A25X-01A 73 years, male, asian, stage:ii, alive, 1779 days 1231.6
                                  TCGA-BC-A69H-01A 64 years, male, white, stage:ii, alive, 444 days 1101.8
                                  Show allShow less
                                  5038.37777.311392.41101.820491.905,00010,00015,00020,00025,00030,00035,000
                                  5038.37777.311392.41101.820491.905,00010,00015,00020,00025,00030,00035,000
                                  LIVER CANCER - Protein expressioni

                                  A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

                                  Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

                                   

                                  Antibody stainingi

                                  Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

                                  Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


                                  Antibody HPA053928
                                   Staining
                                    High
                                    Medium
                                    Low
                                    Not detected
                                   Intensity
                                    Strong
                                    Moderate
                                    Weak
                                    Negative
                                   Quantity
                                    >75%
                                    75%-25%
                                    <25%
                                    None
                                   Location
                                    Nuclear
                                    Cytoplasmic/membranous
                                    Cytoplasmic/membranous,nuclear
                                    None
                                  Click images for details

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                                  The Human Protein Atlas project is funded
                                  by the Knut & Alice Wallenberg Foundation.


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