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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA050162
Strong cytoplasmic positivity was observed in lymphoid tissues, myoepithelial cells, duodenum and Langerhans cells. Lung macrophages, renal glomeruli and pre-menopausal endometrial glands showed additional membranous staining. Adrenal gland, salivary gland, small intestine and bronchus showed moderate staining.
HPA053176
Lymphoid tissue, adrenocortical cells and glandular cells of pre-menopausal uterus displayed strong cytoplasmic staining with additional membranous positivity in pneumocytes. Bronchus, salivary gland and seminal vesicle were moderately stained. Remaining normal tissues were negative.
CAB002798
Lymphatic tissues, blood vessels, glomeruli, fallopian tube showed strong cytoplasmic positivity. Cells in CNS, myocytes and endocrine organs were mainly negative.
CAB015402
Normal tissues showed moderate to strong cytoplasmic staining in a majority of cases. Surface epithelium, placenta, renal tubules, liver and myocytes were negative.