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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
122396.0
nTPM
HPA Brain:
84438.6
nTPM
GTEx:
122396.0
nTPM
Pig:
27368.5
nTPM
Mouse:
7581.1
nTPM
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
84438.6
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 41035.3
2219
Male, age 76, both hemispheres
110593.7
1833
Male, age 53, unknown
47114.2
2666
Male, age 74, left hemisphere
44086.9
1830
Male, age 51, unknown
42517.4
2828
Female, age 72, unknown
36318.5
2586
Male, age 75, left hemisphere
35585.9
1827
Male, age 72, unknown
26008.1
1870
Female, age 42, unknown
25933.1
2019
Male, age 18, unknown
22137.2
2411
Female, age 72, unknown
20058.2
Dorsal raphe nucleus nTPM: 20952.7
1828
Male, age 53, unknown
36411.7
2750
Male, age 76, both hemispheres
27710.1
2047
Male, age 72, unknown
15909.9
2016
Female, age 72, unknown
15826.0
2298
Female, age 72, unknown
8906.0
Inferior colliculus nTPM: 33669.9
2849
Male, age 72, unknown
76211.5
1890
Male, age 53, unknown
24917.8
1848
Female, age 42, unknown
19797.7
2097
Female, age 72, unknown
13752.5
Median raphe nucleus nTPM: 84438.6
2220
Male, age 76, midline
84438.6
Periaquaductal grey, anterior nTPM: 25732.0
2502
Female, age 75, unknown
39280.0
1795
Male, age 51, unknown
20311.0
1947
Male, age 18, unknown
17605.0
Periaquaductal grey, dorsal nTPM: 38606.0
2850
Male, age 76, both hemispheres
78092.7
2464
Female, age 72, unknown
34355.8
1831
Male, age 72, unknown
28088.9
1840
Male, age 53, unknown
13886.6
Periaquaductal grey, lateral nTPM: 20588.7
2140
Male, age 76, both hemispheres
27383.9
2053
Male, age 18, unknown
17393.8
2272
Male, age 74, both hemispheres
16988.4
Pretectal area nTPM: 30601.4
1815
Male, age 53, unknown
46483.1
1816
Male, age 51, unknown
46265.7
1817
Female, age 42, unknown
43471.9
2667
Female, age 75, unknown
39957.0
1944
Female, age 72, unknown
35322.8
2825
Male, age 18, unknown
34864.1
2007
Male, age 72, unknown
23350.9
2407
Male, age 75, both hemispheres
20925.9
2224
Female, age 72, unknown
20238.3
2273
Male, age 74, both hemispheres
13172.3
2316
Male, age 76, right hemisphere
12563.2
Red nucleus nTPM: 32721.7
2503
Female, age 72, unknown
50108.5
1954
Female, age 42, unknown
39475.2
2823
Male, age 76, right hemisphere
38438.9
2227
Male, age 72, unknown
35268.6
2785
Male, age 18, unknown
32083.6
2588
Male, age 74, left hemisphere
32032.9
2725
Female, age 75, unknown
28914.3
2769
Male, age 72, unknown
28743.0
1865
Male, age 51, unknown
28374.6
2584
Male, age 75, left hemisphere
28142.5
1904
Male, age 53, unknown
27989.0
1821
Female, age 72, unknown
23089.5
Substantia nigra nTPM: 36911.7
2699
Male, age 18, unknown
73095.5
2665
Male, age 74, both hemispheres
64961.5
1916
Female, age 42, unknown
44381.1
1941
Male, age 53, unknown
43152.9
2409
Female, age 72, unknown
34080.0
2241
Male, age 72, unknown
28153.4
2583
Male, age 75, right hemisphere
21756.5
1889
Female, age 72, unknown
21134.8
1851
Male, age 51, unknown
20322.0
2590
Female, age 75, unknown
18079.8
Superior colliculus nTPM: 26668.9
2664
Male, age 75, both hemispheres
33750.9
2087
Female, age 72, unknown
32921.4
1839
Male, age 51, unknown
32352.4
1913
Female, age 42, unknown
30219.9
2587
Male, age 74, left hemisphere
24287.9
2261
Male, age 18, unknown
24213.9
1995
Male, age 72, unknown
24087.4
1895
Male, age 76, right hemisphere
23463.8
2668
Female, age 75, unknown
22556.5
1796
Male, age 53, unknown
18835.1
Ventral tegmental area nTPM: 40028.3
2218
Male, age 76, both hemispheres
78126.8
2223
Female, age 72, unknown
53593.7
1942
Male, age 51, unknown
32367.7
1915
Female, age 42, unknown
25904.9
2021
Male, age 53, unknown
25493.8
2410
Female, age 72, unknown
24683.1
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
122396.0
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 122396.0
Samples: 139
Max nTPM: 434897.0
Min nTPM: 20546.7
Std nTPM: 81019.1
Median nTPM: 98659.2
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
