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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
65.1
nTPM
HPA Brain:
75.0
nTPM
GTEx:
65.1
nTPM
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
75.0
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 52.7
2219
Male, age 76, both hemispheres
106.1
2666
Male, age 74, left hemisphere
78.4
1833
Male, age 53, unknown
66.2
1830
Male, age 51, unknown
57.0
1827
Male, age 72, unknown
46.1
2586
Male, age 75, left hemisphere
42.3
2828
Female, age 72, unknown
41.5
1870
Female, age 42, unknown
31.9
2411
Female, age 72, unknown
29.9
2019
Male, age 18, unknown
27.2
Dorsal raphe nucleus nTPM: 37.6
2750
Male, age 76, both hemispheres
48.5
1828
Male, age 53, unknown
44.2
2016
Female, age 72, unknown
35.0
2047
Male, age 72, unknown
31.7
2298
Female, age 72, unknown
28.4
Inferior colliculus nTPM: 49.8
2849
Male, age 72, unknown
91.9
1848
Female, age 42, unknown
47.2
1890
Male, age 53, unknown
33.4
2097
Female, age 72, unknown
26.9
Median raphe nucleus nTPM: 75.0
2220
Male, age 76, midline
75.0
Periaquaductal grey, anterior nTPM: 39.9
1947
Male, age 18, unknown
43.9
1795
Male, age 51, unknown
41.1
2502
Female, age 75, unknown
34.8
Periaquaductal grey, dorsal nTPM: 63.6
2850
Male, age 76, both hemispheres
95.6
2464
Female, age 72, unknown
65.8
1831
Male, age 72, unknown
54.7
1840
Male, age 53, unknown
38.4
Periaquaductal grey, lateral nTPM: 58.3
2140
Male, age 76, both hemispheres
77.7
2272
Male, age 74, both hemispheres
55.7
2053
Male, age 18, unknown
41.6
Pretectal area nTPM: 45.7
2825
Male, age 18, unknown
60.4
2224
Female, age 72, unknown
58.8
2667
Female, age 75, unknown
54.7
2407
Male, age 75, both hemispheres
53.7
2316
Male, age 76, right hemisphere
47.9
1815
Male, age 53, unknown
44.2
1817
Female, age 42, unknown
41.4
1816
Male, age 51, unknown
39.0
2007
Male, age 72, unknown
38.1
1944
Female, age 72, unknown
35.6
2273
Male, age 74, both hemispheres
28.4
Red nucleus nTPM: 40.3
2584
Male, age 75, left hemisphere
63.4
2823
Male, age 76, right hemisphere
60.3
2785
Male, age 18, unknown
40.3
1865
Male, age 51, unknown
40.0
2503
Female, age 72, unknown
39.3
2227
Male, age 72, unknown
39.0
2725
Female, age 75, unknown
38.8
2769
Male, age 72, unknown
35.7
1954
Female, age 42, unknown
32.7
2588
Male, age 74, left hemisphere
32.7
1821
Female, age 72, unknown
32.0
1904
Male, age 53, unknown
29.7
Substantia nigra nTPM: 45.3
1941
Male, age 53, unknown
80.3
2699
Male, age 18, unknown
77.3
2241
Male, age 72, unknown
53.7
2665
Male, age 74, both hemispheres
51.0
2590
Female, age 75, unknown
38.0
2583
Male, age 75, right hemisphere
37.5
1889
Female, age 72, unknown
31.9
1916
Female, age 42, unknown
30.9
1851
Male, age 51, unknown
30.6
2409
Female, age 72, unknown
21.4
Superior colliculus nTPM: 43.9
2664
Male, age 75, both hemispheres
68.1
1839
Male, age 51, unknown
57.9
1895
Male, age 76, right hemisphere
51.0
2668
Female, age 75, unknown
43.9
2587
Male, age 74, left hemisphere
43.5
1913
Female, age 42, unknown
40.0
1796
Male, age 53, unknown
37.7
2261
Male, age 18, unknown
35.7
2087
Female, age 72, unknown
33.5
1995
Male, age 72, unknown
27.4
Ventral tegmental area nTPM: 39.9
2218
Male, age 76, both hemispheres
54.2
2223
Female, age 72, unknown
47.7
2021
Male, age 53, unknown
38.4
1942
Male, age 51, unknown
35.5
1915
Female, age 42, unknown
35.4
2410
Female, age 72, unknown
27.9
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
65.1
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 65.1
Samples: 139
Max nTPM: 172.7
Min nTPM: 3.4
Std nTPM: 37.0
Median nTPM: 62.3
The Human Protein Atlas project is funded
