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ALG1L2
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  • ALG1L2
PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

ALG1L2
Synonyms
Gene descriptioni

Full gene name according to HGNC.

ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Metabolic proteins
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at transcript level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 3
Cytoband q22.1
Chromosome location (bp) 130081831 - 130113227
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
Ensembl ENSG00000251287 (version 109)
Entrez gene 644974
HGNC HGNC:37258
UniProt C9J202 (UniProt - Inferred from homology)
neXtProt NX_C9J202
GeneCards ALG1L2
Antibodypedia ALG1L2 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

Putative glycosyltransferase.... show less
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

Glycosyltransferase, Transferase
Gene summary (Entrez)i

Useful information about the gene from Entrez

Predicted to enable mannosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
ALG1L2-201
ENSP00000479850
ENST00000425059
C9J202
[Direct mapping] Putative glycosyltransferase ALG1L2
Show all
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at transcript level
Protein evidence (Kim et al 2014)
Show all
GO:0000030 [mannosyltransferase activity]
GO:0005783 [endoplasmic reticulum]
GO:0006486 [protein glycosylation]
GO:0016740 [transferase activity]
GO:0016757 [glycosyltransferase activity]
GO:0097502 [mannosylation]
Show all
215 aa
24.2 kDa
No 0
ALG1L2-204
ENSP00000513618
ENST00000698236
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Show all
GO:0000030 [mannosyltransferase activity]
GO:0016757 [glycosyltransferase activity]
Show all
244 aa
27.6 kDa
No 0
ALG1L2-205
ENSP00000513619
ENST00000698237
Metabolic proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Show all
GO:0000030 [mannosyltransferase activity]
GO:0016757 [glycosyltransferase activity]
Show all
231 aa
26.1 kDa
No 0

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