We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
FXYD6-FXYD2
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields ยป
Search result

 
Field
All
Term
Gene name
Class
Blood group antigen proteins
Subclass
 
Class
 
Keyword
Chromosome
External id
Tissue
 
Cell type
 
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Cluster
Reliability
Cell type
Category
Cluster
Tissue
 
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Interacting gene
Number of interactions
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Yes
Protein structure
In atlas
Column
Gene


                        • SPECIFICITY
                        • DISTRIBUTION
                        • EXPRESSION
                        • SPECIFICITY
                        • DISTRIBUTION
                        • EXPRESSION
                        • SPECIFICITY
                        • DISTRIBUTION
                        • EXPRESSION
                        • SPECIFICITY
                        • DISTRIBUTION
                        • EXPRESSION
                        • SPECIFICITY
                        • DISTRIBUTION
                        • EXPRESSION
                          • SPECIFICITY
                          • DISTRIBUTION
                          • EXPRESSION
                          • SPECIFICITY
                          • DISTRIBUTION
                          • EXPRESSION
                          • SPECIFICITY
                          • DISTRIBUTION
                          • EXPRESSION
                          • RELIABILITY
                          • SUBCELLULAR VARIATION
                          • MULTILOCALIZATION
                          • OTHER
                          • SPECIFICITY
                          • DISTRIBUTION
                          • EXPRESSION
                          • Check all
                          • Uncheck all
                                  • SUMMARY

                                  • TISSUE

                                  • BRAIN

                                  • SINGLE CELL

                                  • TISSUE CELL

                                  • PATHOLOGY

                                  • DISEASE

                                  • IMMUNE

                                  • BLOOD

                                  • SUBCELL

                                  • CELL LINE

                                  • STRUCTURE

                                  • INTERACTION

                                  • FXYD6-FXYD2
                                  PATHOLOGY LYMPHOMA Show tissue menu
                                  BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
                                  MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
                                  ANTIBODIES
                                  AND
                                  VALIDATION
                                  Dictionary
                                  Lymphoma
                                  Human pathology
                                  Lymphoma
                                  Interactive survival scatter ploti

                                  The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

                                  The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

                                  Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

                                  Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

                                  & Survival analysisi

                                  Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

                                    Survival analysis data not available.
                                  LYMPHOMA - Protein expressioni

                                  A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

                                  Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

                                   

                                  Antibody stainingi

                                  Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

                                  Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


                                  Antibody HPA068838
                                   Staining
                                    High
                                    Medium
                                    Low
                                    Not detected
                                   Intensity
                                    Strong
                                    Moderate
                                    Weak
                                    Negative
                                   Quantity
                                    >75%
                                    75%-25%
                                    <25%
                                    None
                                   Location
                                    Nuclear
                                    Cytoplasmic/membranous
                                    Cytoplasmic/membranous,nuclear
                                    None
                                  Click images for details

                                  Contact

                                  • NEWS ARTICLES
                                  • PRESS ROOM

                                  The Project

                                  • INTRODUCTION
                                  • ORGANIZATION
                                  • PUBLICATIONS

                                  The Human Protein Atlas

                                  • DOWNLOADABLE DATA
                                  • LICENCE & CITATION
                                  • HELP & FAQ
                                  The Human Protein Atlas project is funded
                                  by the Knut & Alice Wallenberg Foundation.


                                  contact@proteinatlas.org