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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
Medium
Neuronal cells:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
1.3
nTPM
HPA Brain:
30.0
nTPM
GTEx:
1.3
nTPM
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA042201
Glial cells
Medium
Neuronal cells
Not detected
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max nTPM
30.0
Sample id
Sample description
nTPM
Hippocampus nTPM: 23.3
1898
Male, age 80, left hemisphere
29.1
2529
Female, age 94, left hemisphere
25.9
2148
Female, age 91, left hemisphere
25.1
2621
Female, age 67, right hemisphere
24.4
1911
Female, age 85, right hemisphere
19.3
1855
Male, age 76, left hemisphere
16.3
Dentate gyrus nTPM: 24.7
2531
Female, age 67, both hemispheres
31.4
2528
Male, age 74, both hemispheres
30.5
1927
Female, age 91, both hemispheres
24.1
2010
Male, age 76, both hemispheres
22.6
2530
Female, age 94, left hemisphere
20.4
2246
Female, age 85, both hemispheres
19.3
Entorhinal gyrus nTPM: 30.0
2764
Male, age 80, right hemisphere
35.8
2613
Female, age 94, left hemisphere
34.3
2117
Female, age 91, right hemisphere
33.9
1938
Female, age 85, left hemisphere
28.8
1787
Male, age 76, left hemisphere
25.3
2686
Male, age 75, right hemisphere
21.8
Hippocampus, CA1 nTPM: 24.3
2527
Male, age 74, both hemispheres
41.2
2082
Female, age 91, right hemisphere
30.6
2749
Male, age 80, left hemisphere
17.7
2045
Male, age 76, both hemispheres
16.1
1873
Female, age 85, both hemispheres
16.0
Hippocampus, CA2 nTPM: 28.5
2249
Male, age 74, both hemispheres
52.6
1940
Female, age 85, left hemisphere
28.8
2113
Female, age 91, right hemisphere
28.3
2437
Female, age 94, left hemisphere
24.5
1963
Male, age 80, left hemisphere
21.5
1892
Male, age 76, both hemispheres
14.9
Hippocampus, CA3 nTPM: 23.1
2436
Male, age 74, both hemispheres
31.7
2620
Female, age 94, left hemisphere
27.8
1867
Male, age 76, both hemispheres
23.5
2861
Female, age 67, both hemispheres
22.2
1891
Female, age 85, both hemispheres
21.0
2137
Male, age 80, left hemisphere
12.4
Parahippocampal cortex nTPM: 24.9
1990
Female, age 91, right hemisphere
37.6
2250
Female, age 67, right hemisphere
34.5
1933
Female, age 85, both hemispheres
31.0
2245
Female, age 91, both hemispheres
29.4
2532
Female, age 72, left hemisphere
27.3
2018
Male, age 76, both hemispheres
22.1
1850
Male, age 80, both hemispheres
20.2
2622
Female, age 67, right hemisphere
20.2
2693
Female, age 94, both hemispheres
14.5
2692
Male, age 74, both hemispheres
11.8
Perirhinal gyrus nTPM: 24.6
1794
Male, age 80, right hemisphere
30.6
1847
Female, age 91, left hemisphere
30.3
1841
Female, age 85, right hemisphere
24.5
2848
Male, age 76, right hemisphere
21.1
2521
Female, age 94, right hemisphere
16.2
Subiculum nTPM: 23.3
1977
Female, age 85, both hemispheres
40.4
2619
Male, age 74, both hemispheres
26.2
2729
Female, age 91, right hemisphere
24.4
2042
Male, age 76, both hemispheres
21.7
1901
Male, age 80, both hemispheres
20.6
2438
Female, age 94, left hemisphere
6.6
HIPPOCAMPAL FORMATION - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
1.3
GTEx sample id
Sample description
nTPM
Brain - Hippocampus Average nTPM: 1.3
Samples: 197
Max nTPM: 19.3
Min nTPM: 0.0
Std nTPM: 1.6
Median nTPM: 1.1
The Human Protein Atlas project is funded
