CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: Not detected
Neuronal cells: Low
Neuropil: Medium
RNA expressioni
Consensus:56.7 nTPM
HPA:32.0 nTPM
HPA Brain:23.7 nTPM
HPA PFC Brain:30.9 nTPM
GTEx:56.7 nTPM
FANTOM5:63.6 Scaled Tags Per Million
Pig:91.4 nTPM
Mouse:26.2 nTPM
Allen mouse:10.0 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA072658
Endothelial cells Not detected
Glial cells Not detected
Neuronal cells Low
Neuropil Medium



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 32.0
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 35.3
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 20.9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 39.8
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 23.7
Sample id Sample description nTPM
Angular gyrus
nTPM: 15.9
2221 Female, age 67, right hemisphere 22.8
1866 Male, age 76, both hemispheres 22.7
2103 Male, age 75, left hemisphere 19.0
2602 Female, age 94, right hemisphere 16.4
1790 Male, age 76, right hemisphere 14.7
2260 Female, age 72, left hemisphere 12.9
2722 Male, age 61, left hemisphere 9.5
2265 Female, age 91, left hemisphere 9.2
Anterior cingulate cortex, supragenual-dorsal
nTPM: 16.9
2472 Male, age 75, left hemisphere 22.9
1896 Female, age 85, right hemisphere 21.8
2547 Male, age 74, left hemisphere 17.5
2342 Female, age 94, right hemisphere 11.8
2478 Female, age 67, right hemisphere 10.7
Anterior cingulate cortex, supragenual-ventral
nTPM: 14.8
2538 Male, age 75, left hemisphere 17.6
1761 Male, age 74, left hemisphere 16.6
1950 Female, age 85, right hemisphere 16.5
2479 Female, age 67, right hemisphere 11.8
1755 Female, age 94, right hemisphere 11.3
Anterior insular cortex, dorsal
nTPM: 14.0
2506 Female, age 94, right hemisphere 21.2
2670 Male, age 75, left hemisphere 14.8
2001 Male, age 76, right hemisphere 11.2
2235 Female, age 91, right hemisphere 8.6
Anterior insular cortex, ventral
nTPM: 16.6
1925 Female, age 91, left hemisphere 26.4
1852 Male, age 76, left hemisphere 17.5
2507 Female, age 94, left hemisphere 16.3
2757 Male, age 61, right hemisphere 15.1
2262 Female, age 67, right hemisphere 13.9
2596 Male, age 75, left hemisphere 10.7
Area parastriata, inferior
nTPM: 13.5
2234 Male, age 75, left hemisphere 17.3
1760 Female, age 67, left hemisphere 14.9
1789 Male, age 76, right hemisphere 14.8
1758 Female, age 72, right hemisphere 14.7
2268 Male, age 61, right hemisphere 12.4
2509 Female, age 94, left hemisphere 12.1
2421 Female, age 91, left hemisphere 8.4
Area parastriata, parietal
nTPM: 13.4
1785 Male, age 76, right hemisphere 15.1
2680 Female, age 94, right hemisphere 14.3
2236 Female, age 91, left hemisphere 13.6
2420 Male, age 75, left hemisphere 13.4
2233 Male, age 61, right hemisphere 10.4
Area parastriata, superior
nTPM: 13.9
1773 Female, age 91, left hemisphere 21.2
2881 Male, age 76, left hemisphere 15.6
2604 Female, age 94, right hemisphere 13.7
2419 Male, age 75, right hemisphere 13.0
2684 Female, age 67, left hemisphere 12.5
2435 Male, age 61, left hemisphere 7.6
Area parastriata, temporal
nTPM: 16.2
2471 Male, age 75, left hemisphere 19.3
2424 Female, age 67, left hemisphere 18.0
2681 Female, age 94, right hemisphere 16.5
1804 Male, age 76, right hemisphere 15.8
2267 Male, age 61, right hemisphere 11.2
Area striata
nTPM: 12.8
2417 Male, age 61, right hemisphere 17.8
2002 Female, age 91, right hemisphere 14.3
1753 Female, age 72, right hemisphere 12.4
1884 Male, age 76, left hemisphere 11.8
2427 Female, age 91, left hemisphere 10.4
2679 Female, age 94, right hemisphere 10.3
Claustrum
nTPM: 13.1
2392 Female, age 94, both hemispheres 18.5
2198 Male, age 80, both hemispheres 15.4
2196 Female, age 79, unknown 15.1
1956 Male, age 74, unknown 14.4
2568 Male, age 61, both hemispheres 14.4
2645 Female, age 72, unknown 12.7
2491 Male, age 75, both hemispheres 10.2
2284 Female, age 91, both hemispheres 9.8
2292 Female, age 85, both hemispheres 6.9
Frontal eye field
nTPM: 16.7
2147 Male, age 61, left hemisphere 20.4
2761 Female, age 94, left hemisphere 17.0
2543 Male, age 74, left hemisphere 15.5
2441 Male, age 75, left hemisphere 13.8
Frontal operculum
nTPM: 15.7
2348 Male, age 75, left hemisphere 21.0
2030 Male, age 61, right hemisphere 15.5
2781 Female, age 85, right hemisphere 10.5
Fusiform gyrus
nTPM: 15.6
2074 Female, age 91, left hemisphere 20.5
2784 Female, age 85, left hemisphere 18.5
1807 Male, age 76, left hemisphere 17.6
2617 Female, age 94, left hemisphere 17.4
2112 Male, age 80, both hemispheres 16.5
2431 Male, age 75, right hemisphere 11.3
2433 Female, age 72, left hemisphere 7.7
Inferior frontal gyrus, opercular
nTPM: 18.7
2865 Male, age 61, left hemisphere 25.4
2866 Male, age 61, right hemisphere 24.8
2873 Female, age 85, left hemisphere 21.9
2871 Female, age 94, left hemisphere 20.6
2875 Female, age 67, left hemisphere 18.1
2872 Female, age 94, right hemisphere 17.2
2868 Male, age 75, right hemisphere 16.4
2874 Female, age 85, right hemisphere 16.1
2867 Male, age 75, left hemisphere 14.2
2869 Male, age 74, left hemisphere 12.0
Inferior parietal lobule
nTPM: 13.1
2418 Male, age 75, left hemisphere 18.0
2599 Female, age 94, left hemisphere 15.4
2606 Female, age 67, right hemisphere 15.2
2876 Male, age 76, right hemisphere 4.0
Inferior temporal gyrus
nTPM: 18.5
1880 Male, age 80, right hemisphere 25.5
2430 Male, age 75, right hemisphere 24.1
1965 Female, age 91, left hemisphere 18.6
2689 Female, age 94, right hemisphere 16.4
1808 Male, age 76, left hemisphere 14.7
1970 Female, age 85, right hemisphere 11.7
Intraparietal deep sulcus
nTPM: 14.2
2230 Male, age 61, right hemisphere 17.6
2798 Male, age 76, left hemisphere 17.2
2600 Female, age 94, right hemisphere 15.5
2669 Male, age 75, left hemisphere 15.4
2102 Female, age 91, left hemisphere 10.5
2607 Female, age 67, right hemisphere 9.0
Lingual gyrus
nTPM: 15.1
2838 Male, age 80, right hemisphere 16.7
1893 Male, age 76, left hemisphere 16.4
2688 Male, age 75, right hemisphere 16.4
2618 Female, age 94, left hemisphere 13.8
2073 Female, age 85, left hemisphere 12.0
Middle cingulate cortex
nTPM: 15.6
2640 Female, age 94, right hemisphere 18.5
2357 Female, age 67, right hemisphere 18.1
2028 Female, age 85, left hemisphere 15.9
2633 Male, age 74, left hemisphere 15.0
2539 Male, age 75, left hemisphere 10.4
Middle temporal gyrus
nTPM: 17.2
1819 Male, age 80, right hemisphere 23.8
2616 Female, age 94, left hemisphere 19.0
2034 Female, age 91, right hemisphere 16.4
1799 Male, age 76, left hemisphere 13.5
2611 Male, age 75, right hemisphere 13.2
Occipital cortex
nTPM: 14.7
1842 Male, age 76, right hemisphere 16.2
2608 Female, age 67, both hemispheres 14.9
2470 Male, age 75, right hemisphere 14.5
2426 Male, age 75, midline 13.9
2677 Female, age 67, right hemisphere 13.9
Olfactory area
nTPM: 17.7
2756 Female, age 67, right hemisphere 25.0
2222 Female, age 67, right hemisphere 20.7
1805 Female, age 85, right hemisphere 20.1
2352 Female, age 94, right hemisphere 14.1
2440 Male, age 75, left hemisphere 13.9
2542 Male, age 74, left hemisphere 12.4
Olfactory tubercle
nTPM: 21.2
1998 Female, age 91, both hemispheres 25.2
1846 Male, age 80, right hemisphere 23.9
2856 Male, age 75, right hemisphere 18.1
2487 Female, age 94, left hemisphere 17.9
Orbitofrontal gyrus, anterior
nTPM: 12.2
2863 Female, age 85, right hemisphere 19.1
2864 Female, age 67, left hemisphere 10.1
2862 Female, age 85, left hemisphere 7.3
Paracentral lobule, anterior
nTPM: 22.0
1776 Female, age 85, right hemisphere 25.5
1926 Male, age 61, left hemisphere 23.8
2474 Male, age 74, left hemisphere 22.7
1754 Male, age 75, left hemisphere 22.5
2340 Female, age 67, right hemisphere 19.6
2638 Female, age 94, right hemisphere 17.8
Paracentral lobule, posterior
nTPM: 16.9
1775 Female, age 85, right hemisphere 22.9
2345 Male, age 61, left hemisphere 22.6
1764 Male, age 74, right hemisphere 16.3
2551 Female, age 94, right hemisphere 13.4
2446 Male, age 75, left hemisphere 9.3
Parietal operculum
nTPM: 15.1
2356 Female, age 67, right hemisphere 18.9
2719 Male, age 75, left hemisphere 16.3
1763 Male, age 74, left hemisphere 14.8
2552 Female, age 94, right hemisphere 10.4
Parieto-insular cortex
nTPM: 15.5
1976 Female, age 91, right hemisphere 27.9
2671 Male, age 75, left hemisphere 15.2
2831 Male, age 76, right hemisphere 13.3
2232 Male, age 61, right hemisphere 11.3
2508 Female, age 94, right hemisphere 9.8
Parieto-occipital transitional area
nTPM: 13.9
2674 Female, age 94, right hemisphere 17.0
2468 Male, age 75, left hemisphere 15.7
1784 Male, age 76, right hemisphere 14.6
2270 Male, age 61, right hemisphere 11.5
2683 Female, age 67, left hemisphere 11.0
Piriform cortex
nTPM: 10.2
2347 Male, age 75, right hemisphere 12.9
2153 Female, age 85, left hemisphere 7.4
Postcentral gyrus
nTPM: 23.7
2533 Male, age 75, right hemisphere 23.7
Postcentral gyrus, dorsal
nTPM: 20.0
2350 Male, age 75, left hemisphere 23.9
1836 Female, age 85, right hemisphere 23.2
2339 Female, age 67, right hemisphere 22.8
2477 Female, age 94, right hemisphere 21.3
2151 Male, age 61, left hemisphere 15.1
2544 Male, age 74, left hemisphere 13.8
Postcentral gyrus, middle
nTPM: 17.5
1897 Female, age 85, right hemisphere 20.9
2545 Male, age 74, left hemisphere 20.1
2146 Female, age 67, right hemisphere 18.6
2248 Male, age 61, left hemisphere 16.0
2444 Male, age 75, left hemisphere 11.8
Postcentral gyrus, ventral
nTPM: 14.9
2445 Male, age 75, left hemisphere 16.8
2836 Female, age 94, right hemisphere 15.3
2024 Female, age 85, right hemisphere 12.6
Posterior cingulate cortex
nTPM: 17.7
2473 Male, age 75, left hemisphere 19.6
2553 Female, age 94, right hemisphere 19.0
1759 Male, age 74, right hemisphere 14.5
Posterior cingulate cortex, dorsal
nTPM: 12.0
2641 Female, age 94, right hemisphere 17.7
2634 Male, age 74, left hemisphere 13.1
2076 Female, age 85, right hemisphere 12.0
2540 Male, age 75, right hemisphere 11.7
2343 Male, age 61, left hemisphere 8.9
2556 Female, age 67, right hemisphere 8.8
Posterior cingulate cortex, ventral
nTPM: 13.2
2346 Male, age 61, left hemisphere 15.1
1994 Female, age 85, right hemisphere 14.2
2635 Male, age 74, left hemisphere 13.4
1762 Female, age 94, right hemisphere 12.9
2541 Male, age 75, right hemisphere 11.9
2448 Female, age 67, right hemisphere 11.8
Posterior insular cortex
nTPM: 17.1
2832 Female, age 91, right hemisphere 26.4
2603 Female, age 94, left hemisphere 18.1
2511 Female, age 67, right hemisphere 17.7
2597 Male, age 75, left hemisphere 16.0
1823 Male, age 76, right hemisphere 12.8
2231 Male, age 61, left hemisphere 11.7
Precentral gyrus
nTPM: 11.2
2557 Male, age 75, right hemisphere 11.2
Precentral gyrus, dorsal
nTPM: 15.9
1756 Male, age 74, left hemisphere 17.9
2354 Female, age 67, right hemisphere 17.2
2476 Female, age 94, right hemisphere 15.4
2442 Male, age 75, left hemisphere 13.1
Precentral gyrus, middle
nTPM: 18.4
1969 Female, age 67, right hemisphere 29.8
1909 Male, age 61, left hemisphere 22.3
2443 Male, age 75, left hemisphere 14.8
2475 Male, age 74, right hemisphere 13.1
2549 Female, age 94, right hemisphere 11.9
Precentral gyrus, ventral
nTPM: 19.5
2662 Female, age 67, right hemisphere 28.2
2678 Male, age 74, left hemisphere 18.9
2550 Female, age 94, right hemisphere 16.1
2630 Male, age 75, left hemisphere 14.8
Precuneus
nTPM: 13.8
2673 Female, age 94, right hemisphere 16.5
1782 Male, age 76, right hemisphere 15.2
2467 Male, age 75, right hemisphere 14.9
1780 Female, age 91, right hemisphere 14.0
2510 Female, age 67, right hemisphere 11.2
2594 Male, age 61, left hemisphere 11.1
Premotor cortex, dorsal
nTPM: 16.8
2027 Male, age 61, left hemisphere 21.5
1878 Female, age 85, right hemisphere 20.9
2536 Male, age 75, left hemisphere 14.5
2631 Male, age 74, left hemisphere 13.8
2554 Female, age 67, right hemisphere 13.2
Premotor cortex, ventral
nTPM: 20.4
1777 Female, age 67, left hemisphere 33.4
1881 Female, age 85, right hemisphere 22.5
1779 Male, age 61, left hemisphere 19.3
2637 Female, age 94, right hemisphere 17.4
1757 Male, age 74, left hemisphere 15.8
2349 Male, age 75, left hemisphere 14.3
Retrosplenial cortex
nTPM: 19.3
1951 Male, age 61, right hemisphere 24.2
1914 Male, age 76, right hemisphere 17.6
2675 Female, age 94, left hemisphere 16.1
Subcentral gyrus, S2
nTPM: 13.7
2072 Male, age 61, left hemisphere 16.5
2762 Male, age 74, left hemisphere 15.2
2351 Male, age 75, left hemisphere 14.5
2839 Female, age 94, right hemisphere 13.8
1964 Female, age 85, right hemisphere 13.3
2555 Female, age 67, right hemisphere 9.0
Superior parietal lobule
nTPM: 15.6
1992 Female, age 91, right hemisphere 22.1
1800 Male, age 76, right hemisphere 17.0
2229 Male, age 61, right hemisphere 14.4
2605 Female, age 67, right hemisphere 13.8
2672 Female, age 94, right hemisphere 10.5
Superior temporal gyrus
nTPM: 18.5
1844 Female, age 91, left hemisphere 30.1
2615 Female, age 94, left hemisphere 21.2
1843 Male, age 76, left hemisphere 14.6
2025 Male, age 80, right hemisphere 14.1
2687 Male, age 75, right hemisphere 12.7
Supplementary motor cortex
nTPM: 15.6
1993 Male, age 61, left hemisphere 22.8
2632 Male, age 74, left hemisphere 16.5
2537 Male, age 75, left hemisphere 13.3
2548 Female, age 94, right hemisphere 9.9
Supramarginal gyrus
nTPM: 12.6
1991 Female, age 91, right hemisphere 16.6
1798 Male, age 76, right hemisphere 12.4
2415 Male, age 61, left hemisphere 12.4
2513 Female, age 72, left hemisphere 11.9
2601 Female, age 94, left hemisphere 9.7
Temporal pole
nTPM: 21.3
1832 Female, age 91, left hemisphere 32.4
1853 Female, age 85, right hemisphere 26.1
2518 Male, age 75, right hemisphere 19.8
2612 Female, age 94, left hemisphere 17.0
1826 Male, age 76, right hemisphere 11.4
Temporo-insular cortex, parainsular gyrus
nTPM: 12.1
2598 Male, age 75, left hemisphere 16.5
1802 Male, age 76, left hemisphere 16.2
2676 Female, age 94, right hemisphere 11.5
2416 Male, age 61, right hemisphere 11.3
2512 Female, age 67, right hemisphere 8.7
2264 Female, age 91, right hemisphere 8.6
Temporo-occipital transitional zone
nTPM: 15.6
1793 Male, age 80, right hemisphere 23.5
1900 Male, age 76, left hemisphere 14.0
2251 Female, age 85, right hemisphere 9.4
Transversal temporal gyrus, anterior
nTPM: 17.9
1888 Female, age 91, left hemisphere 28.0
2610 Male, age 75, right hemisphere 17.8
2522 Female, age 94, left hemisphere 15.8
1910 Male, age 80, right hemisphere 15.7
1809 Male, age 76, right hemisphere 12.4
Transversal temporal gyrus, posterior
nTPM: 16.2
2833 Male, age 80, right hemisphere 23.1
1967 Female, age 91, right hemisphere 18.6
2614 Female, age 94, left hemisphere 14.4
2520 Male, age 75, right hemisphere 12.7
1922 Male, age 76, left hemisphere 12.5

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 30.9
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 19.8
1516 Female, age 85, left hemisphere 33.6
1511 Male, age 61, right hemisphere 24.6
1510 Male, age 61, left hemisphere 23.4
1512 Male, age 75, left hemisphere 21.0
1517 Female, age 67, left hemisphere 17.5
1515 Female, age 94, right hemisphere 16.9
1518 Female, age 67, right hemisphere 16.7
1513 Male, age 74, left hemisphere 12.8
1514 Male, age 74, right hemisphere 11.9
Anterior cingulate gyrus, pregenual-ventral
nTPM: 20.5
1520 Male, age 75, right hemisphere 26.2
1523 Female, age 67, left hemisphere 24.5
1519 Male, age 61, left hemisphere 22.2
1521 Male, age 74, left hemisphere 15.3
1522 Male, age 74, right hemisphere 14.4
Anterior cingulate gyrus, subgenual
nTPM: 21.5
1529 Female, age 85, left hemisphere 41.9
1530 Female, age 67, right hemisphere 23.5
1526 Male, age 75, right hemisphere 20.9
1524 Male, age 61, left hemisphere 20.2
1525 Male, age 75, left hemisphere 18.2
1528 Male, age 74, right hemisphere 14.8
1527 Male, age 74, left hemisphere 10.9
Dorsolateral prefrontal cortex
nTPM: 20.6
1449 Female, age 85, right hemisphere 28.5
1445 Male, age 75, right hemisphere 22.8
1444 Male, age 75, left hemisphere 22.7
1448 Female, age 94, right hemisphere 18.2
1450 Female, age 67, right hemisphere 18.0
1447 Female, age 94, left hemisphere 17.8
1446 Male, age 74, right hemisphere 16.2
Dorsomedial prefrontal cortex
nTPM: 24.9
1439 Male, age 61, left hemisphere 37.3
1440 Male, age 61, right hemisphere 28.5
1441 Male, age 75, left hemisphere 22.4
1443 Female, age 67, right hemisphere 18.5
1442 Male, age 75, right hemisphere 17.8
Frontal cortex
nTPM: 27.7
1581 Female, age 85, right hemisphere 59.6
1580 Female, age 85, left hemisphere 46.6
1582 Female, age 67, left hemisphere 30.8
1572 Male, age 61, left hemisphere 26.8
1573 Male, age 61, right hemisphere 24.8
1583 Female, age 67, right hemisphere 24.6
1575 Male, age 75, right hemisphere 22.7
1579 Female, age 94, right hemisphere 21.4
1574 Male, age 75, left hemisphere 21.0
1576 Male, age 74, left hemisphere 19.6
1578 Female, age 94, left hemisphere 17.4
1577 Male, age 74, right hemisphere 16.8
Frontomarginal cortex
nTPM: 29.1
1471 Female, age 85, left hemisphere 63.6
1466 Male, age 61, right hemisphere 36.8
1467 Male, age 75, right hemisphere 32.6
1465 Male, age 61, left hemisphere 32.2
1473 Female, age 67, right hemisphere 23.7
1472 Female, age 67, left hemisphere 23.6
1468 Male, age 74, left hemisphere 17.1
1470 Female, age 94, right hemisphere 16.4
1469 Female, age 94, left hemisphere 15.7
Frontopolar cortex
nTPM: 27.6
1459 Male, age 61, right hemisphere 44.0
1458 Male, age 61, left hemisphere 35.6
1461 Male, age 75, right hemisphere 33.2
1460 Male, age 75, left hemisphere 25.2
1463 Female, age 67, left hemisphere 20.4
1464 Female, age 67, right hemisphere 19.7
1462 Female, age 94, left hemisphere 15.0
Gyrus rectus
nTPM: 29.1
1480 Female, age 85, left hemisphere 49.2
1475 Male, age 61, right hemisphere 45.5
1477 Male, age 75, right hemisphere 29.6
1474 Male, age 61, left hemisphere 25.7
1476 Male, age 75, left hemisphere 24.7
1481 Female, age 67, left hemisphere 21.4
1478 Female, age 94, left hemisphere 20.3
1479 Female, age 94, right hemisphere 16.3
Inferior frontal gyrus, orbital
nTPM: 24.0
1501 Male, age 61, right hemisphere 48.8
1508 Female, age 85, right hemisphere 42.1
1500 Male, age 61, left hemisphere 32.3
1502 Male, age 75, left hemisphere 20.1
1505 Male, age 74, right hemisphere 19.0
1503 Male, age 75, right hemisphere 18.4
1509 Female, age 67, right hemisphere 17.0
1507 Female, age 85, left hemisphere 15.9
1504 Male, age 74, left hemisphere 15.5
1506 Female, age 94, left hemisphere 11.0
Inferior frontal gyrus, triangular
nTPM: 21.9
1548 Female, age 85, right hemisphere 41.6
1543 Male, age 61, right hemisphere 28.3
1542 Male, age 61, left hemisphere 26.0
1549 Female, age 67, left hemisphere 21.7
1547 Female, age 85, left hemisphere 19.8
1544 Male, age 75, right hemisphere 16.1
1546 Female, age 94, right hemisphere 12.4
1545 Male, age 74, right hemisphere 9.6
Orbitofrontal gyrus, lateral
nTPM: 22.0
1498 Female, age 85, right hemisphere 38.2
1493 Male, age 61, right hemisphere 32.9
1494 Male, age 75, left hemisphere 20.8
1499 Female, age 67, right hemisphere 17.4
1497 Female, age 85, left hemisphere 16.1
1496 Female, age 94, right hemisphere 14.9
1495 Female, age 94, left hemisphere 13.5
Orbitofrontal gyrus, medial
nTPM: 24.6
1490 Female, age 85, right hemisphere 39.9
1489 Female, age 85, left hemisphere 33.5
1482 Male, age 61, left hemisphere 31.8
1483 Male, age 75, left hemisphere 24.4
1484 Male, age 75, right hemisphere 24.3
1492 Female, age 67, right hemisphere 22.5
1487 Female, age 94, left hemisphere 21.0
1491 Female, age 67, left hemisphere 20.1
1485 Male, age 74, left hemisphere 18.8
1488 Female, age 94, right hemisphere 17.8
1486 Male, age 74, right hemisphere 16.1
Orbitofrontal gyrus, posterior
nTPM: 22.0
1539 Female, age 85, right hemisphere 33.4
1531 Male, age 61, left hemisphere 31.9
1532 Male, age 61, right hemisphere 31.5
1538 Female, age 85, left hemisphere 30.8
1533 Male, age 75, left hemisphere 21.1
1541 Female, age 67, right hemisphere 19.3
1534 Male, age 75, right hemisphere 18.3
1540 Female, age 67, left hemisphere 18.0
1536 Female, age 94, left hemisphere 14.8
1537 Female, age 94, right hemisphere 12.1
1535 Male, age 74, left hemisphere 10.3
Subcallosal gyrus
nTPM: 27.1
1559 Female, age 85, right hemisphere 46.9
1558 Female, age 85, left hemisphere 45.8
1550 Male, age 61, left hemisphere 38.9
1551 Male, age 61, right hemisphere 29.1
1561 Female, age 67, right hemisphere 27.8
1553 Male, age 75, right hemisphere 24.9
1552 Male, age 75, left hemisphere 21.4
1556 Female, age 94, left hemisphere 19.7
1557 Female, age 94, right hemisphere 19.0
1555 Male, age 74, right hemisphere 17.4
1560 Female, age 67, left hemisphere 17.3
1554 Male, age 74, left hemisphere 16.5
Superior frontal gyrus
nTPM: 28.7
1569 Female, age 85, left hemisphere 54.6
1570 Female, age 85, right hemisphere 41.2
1562 Male, age 61, left hemisphere 37.8
1563 Male, age 61, right hemisphere 29.6
1565 Male, age 75, right hemisphere 26.5
1564 Male, age 75, left hemisphere 23.7
1568 Female, age 94, right hemisphere 22.2
1571 Female, age 67, right hemisphere 21.0
1567 Female, age 94, left hemisphere 17.8
1566 Male, age 74, right hemisphere 12.9
Temporal cortex
nTPM: 22.2
1596 Female, age 85, right hemisphere 39.9
1590 Male, age 61, right hemisphere 28.7
1591 Male, age 75, right hemisphere 20.9
1592 Male, age 74, left hemisphere 20.4
1594 Female, age 94, left hemisphere 17.9
1593 Male, age 74, right hemisphere 15.8
1595 Female, age 94, right hemisphere 11.9
Ventrolateral prefrontal cortex
nTPM: 18.5
1455 Female, age 85, right hemisphere 31.6
1451 Male, age 75, right hemisphere 22.8
1457 Female, age 67, right hemisphere 17.3
1453 Male, age 74, right hemisphere 16.5
1454 Female, age 94, left hemisphere 15.4
1452 Male, age 74, left hemisphere 14.4
1456 Female, age 67, left hemisphere 11.6
Ventromedial prefrontal cortex
nTPM: 30.9
1436 Female, age 85, left hemisphere 60.5
1432 Male, age 61, left hemisphere 36.9
1433 Male, age 61, right hemisphere 36.3
1437 Female, age 85, right hemisphere 33.7
1434 Male, age 75, right hemisphere 24.2
1438 Female, age 67, left hemisphere 13.5
1435 Female, age 94, right hemisphere 10.9

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 56.7
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 51.9
Samples: 176

Max nTPM: 98.0
Min nTPM: 21.1
Std nTPM: 14.5
Median nTPM: 51.7
GTEX-QVUS-0011-R3A-SM-3GAFD 60-69 years, female 98.0
GTEX-1JMPZ-0011-R3a-SM-EYYWX 30-39 years, male 88.9
GTEX-1F7RK-0011-R3b-SM-9OSWJ 20-29 years, female 80.3
GTEX-14JIY-0011-R3a-SM-5YYAQ 60-69 years, male 80.1
GTEX-1I1GR-0011-R3a-SM-CM2T4 60-69 years, male 79.3
GTEX-131YS-0011-R3b-SM-5DUXB 60-69 years, female 78.4
GTEX-1F75A-0011-R3b-SM-ARL8K 50-59 years, male 78.4
GTEX-T2IS-0011-R3A-SM-32QPB 20-29 years, female 77.6
GTEX-ZAB4-0011-R3a-SM-4RGNQ 40-49 years, male 77.6
GTEX-139TT-0011-R3b-SM-5K7VL 60-69 years, male 76.8
GTEX-17F97-0011-R3b-SM-7LT9E 50-59 years, male 76.0
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Brain - Cortex
Average nTPM: 47.7
Samples: 255

Max nTPM: 80.6
Min nTPM: 18.3
Std nTPM: 9.6
Median nTPM: 47.9
GTEX-X4XY-3026-SM-EWRM9 60-69 years, male 80.6
GTEX-TSE9-3026-SM-3DB76 60-69 years, female 76.4
GTEX-OHPN-2526-SM-2I5H3 60-69 years, female 75.0
GTEX-PVOW-2526-SM-2XCF7 40-49 years, male 71.2
GTEX-QMR6-1426-SM-32PLA 50-59 years, male 68.8
GTEX-1B933-3126-SM-7P8RL 50-59 years, female 66.4
GTEX-1HT8W-3026-SM-CGQEO 30-39 years, male 65.5
GTEX-T2IS-3026-SM-32QPM 20-29 years, female 65.1
GTEX-1HCU6-3126-SM-CL54L 60-69 years, female 65.1
GTEX-1HCVE-3026-SM-CL54G 50-59 years, male 64.5
GTEX-T6MN-2626-SM-32PMQ 50-59 years, male 64.4
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Brain - Frontal Cortex (BA9)
Average nTPM: 56.7
Samples: 209

Max nTPM: 89.2
Min nTPM: 20.0
Std nTPM: 12.9
Median nTPM: 57.9
GTEX-14PJO-0011-R10a-SM-686ZS 60-69 years, male 89.2
GTEX-P44H-0011-R10A-SM-2XCEK 40-49 years, male 87.8
GTEX-1B8L1-0011-R10b-SM-7P8Q4 60-69 years, male 85.6
GTEX-QVUS-0011-R10A-SM-3GIK3 60-69 years, female 84.2
GTEX-13SLX-0011-R10a-SM-5P9HV 50-59 years, female 84.0
GTEX-T6MN-0011-R10A-SM-32QP7 50-59 years, male 82.3
GTEX-1EX96-0011-R10b-SM-CE6QR 50-59 years, male 81.8
GTEX-1B8SF-0011-R10b-SM-7P8SW 60-69 years, male 79.9
GTEX-1HCU6-0011-R10a-SM-CKZP8 60-69 years, female 76.0
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 75.9
GTEX-12ZZY-0011-R10b-SM-5HL7W 60-69 years, male 75.5
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 63.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 42.3
FF:10163-103B1 76 years, female 42.3
Postcentral gyrus
Scaled Tags Per Million: 42.8
FF:10032-101E5 44-52 years, mixed 42.8
Frontal lobe
Scaled Tags Per Million: 63.6
FF:10040-101F4 32-61 years, mixed 63.6
Insula
Scaled Tags Per Million: 47.5
FF:10039-101F3 20-68 years, mixed 47.5
Medial frontal gyrus
Scaled Tags Per Million: 46.9
FF:10150-102I6 76 years, female 46.9
Medial temporal gyrus
Scaled Tags Per Million: 56.7
FF:10183-103D3 60 years, female 66.9
FF:10156-103A3 76 years, female 46.6
Occipital lobe
Scaled Tags Per Million: 52.6
FF:10076-102A4 27 years, male 52.6
Occipital pole
Scaled Tags Per Million: 34.9
FF:10036-101E9 22-68 years, mixed 34.9
Paracentral gyrus
Scaled Tags Per Million: 57.7
FF:10035-101E8 22-69 years, mixed 57.7
Parietal lobe
Scaled Tags Per Million: 50.5
FF:10171-103B9 60 years, female 55.7
FF:10034-101E7 35-89 years, mixed 48.1
FF:10157-103A4 76 years, female 47.6
Temporal lobe
Scaled Tags Per Million: 34.8
FF:10031-101E4 32-61 years, mixed 34.8

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 91.4
Pig sample Sample description nTPM
Occipital cortex
nTPM: 91.4
Samples: 4

Max nTPM: 115.4
Min nTPM: 66.3
Sample A Female 91.1
Sample B Female 115.4
Sample C Male 92.8
Sample D Male 66.3
Retrosplenial cortex
nTPM: 71.5
Samples: 4

Max nTPM: 79.3
Min nTPM: 65.0
Sample A Female 79.3
Sample B Female 65.3
Sample C Male 76.3
Sample D Male 65.0
Cingulate cortex
nTPM: 81.5
Samples: 4

Max nTPM: 114.9
Min nTPM: 58.7
Sample A Female 114.9
Sample B Female 58.7
Sample C Male 90.4
Sample D Male 61.9
Insular cortex
nTPM: 64.4
Samples: 4

Max nTPM: 101.0
Min nTPM: 48.5
Sample A Female 101.0
Sample B Female 54.6
Sample C Male 53.4
Sample D Male 48.5
Motor cortex
nTPM: 87.7
Samples: 4

Max nTPM: 113.1
Min nTPM: 64.0
Sample A Female 113.1
Sample B Female 65.1
Sample C Male 108.6
Sample D Male 64.0
Prefrontal cortex
nTPM: 90.3
Samples: 4

Max nTPM: 126.7
Min nTPM: 64.6
Sample A Female 126.7
Sample B Female 91.2
Sample C Male 78.5
Sample D Male 64.6
Somatosensory cortex
nTPM: 86.5
Samples: 3

Max nTPM: 88.2
Min nTPM: 84.4
Sample B Female 84.4
Sample C Male 87.0
Sample D Male 88.2
Temporal cortex
nTPM: 77.6
Samples: 4

Max nTPM: 81.2
Min nTPM: 68.3
Sample A Female 80.5
Sample B Female 68.3
Sample C Male 81.2
Sample D Male 80.2

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 26.2
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 22.8
Samples: 4

Max nTPM: 29.0
Min nTPM: 17.8
Sample A Male 29.0
Sample B Male 21.5
Sample C Female 17.8
Sample D Female 22.8
Frontal cortex
nTPM: 22.1
Samples: 4

Max nTPM: 27.8
Min nTPM: 13.0
Sample A Male 13.0
Sample B Male 27.8
Sample C Female 27.8
Sample D Female 19.8
Retrosplenial and cingulate cortex
nTPM: 25.6
Samples: 4

Max nTPM: 32.1
Min nTPM: 18.2
Sample A Male 32.1
Sample B Male 26.2
Sample C Female 26.0
Sample D Female 18.2
Somatosensory cortex
nTPM: 26.2
Samples: 4

Max nTPM: 29.4
Min nTPM: 21.9
Sample A Male 21.9
Sample B Male 29.2
Sample C Female 29.4
Sample D Female 24.2

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 10.0
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 10.0
81654147 Antisense, RP_090303_01_A03, Mouse strain C57BL/6J (56 days, male) 10.0
68341890 Antisense, RP_041207_02_D05, Mouse strain C57BL/6J (56 days, male) 3.1
Cerebral cortex
Expression energy: 10.0
81654147 Antisense, RP_090303_01_A03, Mouse strain C57BL/6J (56 days, male) 10.0
68341890 Antisense, RP_041207_02_D05, Mouse strain C57BL/6J (56 days, male) 3.1

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