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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
High
Neuronal cells:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
HPA Brain:
124.9
nTPM
FANTOM5:
8.0
Scaled Tags Per Million
Pig:
80.4
nTPM
Mouse:
0.6
nTPM
Allen mouse:
15.8
Expression energy
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA041189
Glial cells
High
Neuronal cells
High
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max nTPM
124.9
Sample id
Sample description
nTPM
Hippocampus nTPM: 124.4
1855
Male, age 76, left hemisphere
137.7
2529
Female, age 94, left hemisphere
133.6
1898
Male, age 80, left hemisphere
131.1
1911
Female, age 85, right hemisphere
124.6
2621
Female, age 67, right hemisphere
117.6
2148
Female, age 91, left hemisphere
102.0
Dentate gyrus nTPM: 109.4
2528
Male, age 74, both hemispheres
117.7
2010
Male, age 76, both hemispheres
117.1
2530
Female, age 94, left hemisphere
117.1
2531
Female, age 67, both hemispheres
113.8
2246
Female, age 85, both hemispheres
104.2
1927
Female, age 91, both hemispheres
86.6
Entorhinal gyrus nTPM: 110.7
2117
Female, age 91, right hemisphere
143.6
1787
Male, age 76, left hemisphere
115.6
2686
Male, age 75, right hemisphere
110.6
1938
Female, age 85, left hemisphere
102.3
2764
Male, age 80, right hemisphere
100.8
2613
Female, age 94, left hemisphere
91.3
Hippocampus, CA1 nTPM: 124.9
2749
Male, age 80, left hemisphere
143.5
2045
Male, age 76, both hemispheres
139.0
2082
Female, age 91, right hemisphere
133.7
1873
Female, age 85, both hemispheres
107.0
2527
Male, age 74, both hemispheres
101.3
Hippocampus, CA2 nTPM: 120.7
1940
Female, age 85, left hemisphere
143.1
2249
Male, age 74, both hemispheres
122.2
1892
Male, age 76, both hemispheres
120.9
2113
Female, age 91, right hemisphere
117.9
1963
Male, age 80, left hemisphere
114.7
2437
Female, age 94, left hemisphere
105.2
Hippocampus, CA3 nTPM: 119.5
2436
Male, age 74, both hemispheres
144.3
2137
Male, age 80, left hemisphere
127.4
1867
Male, age 76, both hemispheres
124.9
1891
Female, age 85, both hemispheres
113.4
2620
Female, age 94, left hemisphere
104.7
2861
Female, age 67, both hemispheres
102.2
Parahippocampal cortex nTPM: 96.5
2250
Female, age 67, right hemisphere
129.1
2018
Male, age 76, both hemispheres
126.0
1933
Female, age 85, both hemispheres
104.6
2245
Female, age 91, both hemispheres
101.9
1990
Female, age 91, right hemisphere
99.1
2532
Female, age 72, left hemisphere
87.7
2622
Female, age 67, right hemisphere
81.2
2693
Female, age 94, both hemispheres
79.5
1850
Male, age 80, both hemispheres
79.3
2692
Male, age 74, both hemispheres
76.7
Perirhinal gyrus nTPM: 97.5
1794
Male, age 80, right hemisphere
104.1
1847
Female, age 91, left hemisphere
101.8
1841
Female, age 85, right hemisphere
98.3
2521
Female, age 94, right hemisphere
93.0
2848
Male, age 76, right hemisphere
90.2
Subiculum nTPM: 116.0
2042
Male, age 76, both hemispheres
141.2
2729
Female, age 91, right hemisphere
123.7
1901
Male, age 80, both hemispheres
117.9
2619
Male, age 74, both hemispheres
112.1
1977
Female, age 85, both hemispheres
101.6
2438
Female, age 94, left hemisphere
99.9
HIPPOCAMPAL FORMATION - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
0.6
Mouse sample
Sample description
nTPM
Entorhinal cortex nTPM: 0.5
Samples: 4
Max nTPM: 1.1
Min nTPM: 0.0
Sample A
Male
1.1
Sample B
Male
0.0
Sample C
Female
1.0
Sample D
Female
0.0
Hippocampal formation nTPM: 0.6
Samples: 4
Max nTPM: 1.3
Min nTPM: 0.0
Sample A
Male
1.1
Sample B
Male
0.0
Sample C
Female
0.0
Sample D
Female
1.3
HIPPOCAMPAL FORMATION - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
The Human Protein Atlas project is funded
