We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
VPS4B
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Cluster
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Interacting gene
Number of interactions
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • INTERACTION

  • VPS4B
IMMUNE CELL B-CELLS Show tissue menu
B-CELLS DENDRITIC CELLS GRANULOCYTES MONOCYTES NK-CELLS PROGENITORS T-CELLS TOTAL PBMC
Immune cell proteome
B-cells
B-CELLS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA:73.8 nTPM
Monaco:82.6 nTPM
Schmiedel:80.4 TPM

B-CELLS - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM 73.8
HPA sample nTPM
Memory B-cell
nTPM: 65.1
Samples: 6

Max nTPM: 113.8
Min nTPM: 36.5
P10809_1017 36.5
P10809_1025 67.9
P10809_1044 113.8
P10809_1063 65.0
P10809_1092 58.7
P10809_1105 48.4
Naive B-cell
nTPM: 73.8
Samples: 6

Max nTPM: 157.9
Min nTPM: 37.3
P10809_1011 37.3
P10809_1029 57.4
P10809_1048 157.9
P10809_1067 67.9
P10809_1091 62.4
P10809_1104 59.6

B-CELLS - Monaco RNA-seqi

RNA-Seq data generated by Monaco et al is reported as average nTPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max nTPM 82.6
Monaco sample nTPM
Exhausted memory B-cell
nTPM: 80.0
Samples: 4

Max nTPM: 92.0
Min nTPM: 63.1
RHH5310_R3677 91.7
RHH5218_R3590 63.1
RHH5247_R3619 92.0
RHH5276_R3648 73.2
Naive B-cell
nTPM: 82.6
Samples: 4

Max nTPM: 95.1
Min nTPM: 74.3
RHH5308_R3675 74.3
RHH5216_R3588 95.1
RHH5245_R3617 80.1
RHH5274_R3646 80.7
Non-switched memory B-cell
nTPM: 80.6
Samples: 4

Max nTPM: 95.6
Min nTPM: 59.8
RHH5309_R3676 84.5
RHH5217_R3589 59.8
RHH5246_R3618 82.4
RHH5275_R3647 95.6
Plasmablast
nTPM: 64.8
Samples: 4

Max nTPM: 82.2
Min nTPM: 51.6
RHH5312_R3679 82.2
RHH5220_R3592 64.9
RHH5249_R3621 51.6
RHH5278_R3650 60.6
Switched memory B-cell
nTPM: 77.5
Samples: 4

Max nTPM: 96.3
Min nTPM: 61.6
RHH5311_R3678 81.0
RHH5219_R3591 71.2
RHH5248_R3620 96.3
RHH5277_R3649 61.6

B-CELLS - Schmiedel RNA-seqi

RNA-Seq data generated by Schmiedel et al is reported as average TPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. TPM values of the individual samples are presented next to the box plot.

Max TPM 80.4
Schmiedel sample id TPM
Naive B-cell
TPM: 80.4
Samples: 91

Max TPM: 112.4
Min TPM: 58.6
B_CELL_NAIVE_1 112.4
B_CELL_NAIVE_2 112.4
B_CELL_NAIVE_3 110.1
B_CELL_NAIVE_4 104.1
B_CELL_NAIVE_5 100.5
B_CELL_NAIVE_6 99.6
B_CELL_NAIVE_7 98.5
B_CELL_NAIVE_8 97.9
B_CELL_NAIVE_9 96.7
B_CELL_NAIVE_10 95.4
B_CELL_NAIVE_11 95.0
B_CELL_NAIVE_12 92.9
B_CELL_NAIVE_13 92.6
B_CELL_NAIVE_14 92.5
B_CELL_NAIVE_15 91.1
B_CELL_NAIVE_16 90.3
B_CELL_NAIVE_17 90.0
B_CELL_NAIVE_18 88.0
B_CELL_NAIVE_19 87.7
B_CELL_NAIVE_20 87.5
B_CELL_NAIVE_21 87.2
B_CELL_NAIVE_22 86.5
B_CELL_NAIVE_23 85.2
B_CELL_NAIVE_24 84.4
B_CELL_NAIVE_25 84.1
B_CELL_NAIVE_26 83.7
B_CELL_NAIVE_27 83.4
B_CELL_NAIVE_28 82.6
B_CELL_NAIVE_29 82.4
B_CELL_NAIVE_30 82.3
B_CELL_NAIVE_31 82.0
B_CELL_NAIVE_32 81.7
B_CELL_NAIVE_33 81.4
B_CELL_NAIVE_34 81.3
B_CELL_NAIVE_35 80.9
B_CELL_NAIVE_36 80.8
B_CELL_NAIVE_37 80.5
B_CELL_NAIVE_38 80.4
B_CELL_NAIVE_39 80.1
B_CELL_NAIVE_40 79.9
B_CELL_NAIVE_41 79.8
B_CELL_NAIVE_42 79.6
B_CELL_NAIVE_43 79.2
B_CELL_NAIVE_44 79.2
B_CELL_NAIVE_45 79.0
B_CELL_NAIVE_46 78.9
B_CELL_NAIVE_47 78.8
B_CELL_NAIVE_48 78.5
B_CELL_NAIVE_49 78.5
B_CELL_NAIVE_50 77.8
B_CELL_NAIVE_51 77.5
B_CELL_NAIVE_52 77.4
B_CELL_NAIVE_53 77.3
B_CELL_NAIVE_54 77.2
B_CELL_NAIVE_55 77.2
B_CELL_NAIVE_56 77.1
B_CELL_NAIVE_57 77.0
B_CELL_NAIVE_58 76.9
B_CELL_NAIVE_59 76.7
B_CELL_NAIVE_60 76.7
B_CELL_NAIVE_61 76.1
B_CELL_NAIVE_62 75.8
B_CELL_NAIVE_63 75.7
B_CELL_NAIVE_64 75.0
B_CELL_NAIVE_65 74.2
B_CELL_NAIVE_66 74.1
B_CELL_NAIVE_67 73.7
B_CELL_NAIVE_68 73.7
B_CELL_NAIVE_69 73.5
B_CELL_NAIVE_70 72.9
B_CELL_NAIVE_71 72.0
B_CELL_NAIVE_72 71.8
B_CELL_NAIVE_73 71.7
B_CELL_NAIVE_74 71.4
B_CELL_NAIVE_75 70.7
B_CELL_NAIVE_76 70.1
B_CELL_NAIVE_77 69.6
B_CELL_NAIVE_78 69.5
B_CELL_NAIVE_79 69.1
B_CELL_NAIVE_80 68.4
B_CELL_NAIVE_81 68.3
B_CELL_NAIVE_82 68.3
B_CELL_NAIVE_83 67.5
B_CELL_NAIVE_84 67.1
B_CELL_NAIVE_85 66.6
B_CELL_NAIVE_86 66.6
B_CELL_NAIVE_87 66.1
B_CELL_NAIVE_88 65.5
B_CELL_NAIVE_89 63.8
B_CELL_NAIVE_90 60.1
B_CELL_NAIVE_91 58.6
Show allShow less

Contact

  • NEWS ARTICLES
  • PRESS ROOM

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org