In the Interaction summary a network plot of the gene's interaction partners is shown with nodes representing genes and edges representing the interaction type and the confidence (MI score) for the interaction. The type of interaction (direct interaction or physical association) is reflected by the colour of the edges, while the confidence of the interaction is reflected by the thickness of the edges. Scores larger than 0.6 (high confidence) have a thicker line than scores between 0.45 and 0.6 (medium confidence).

The highlight bar in the top of the plot can be used to colour the nodes according to subcellular location (based on data in the Subcellular section), predicted location (based on signalpeptide and transmembrane region predictions), tissue specificity (based on RNA tissue expression profiles) or proteinclass.

Nodes can also be highlighted using the top left Filter option in which a query of choice can be built to for example label all nodes that are tissue enriched in both human and mouse brain or those that belongs to a certain tissue expression cluster. The expression cluster for the gene is stated in the box Human Protein Atlas Information above the network plot. Click on Filter in the top left in the plot to find the query builder and some example queries.