We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
TSC22D3
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Cluster
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Interacting gene
Number of interactions
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • INTERACTION

  • TSC22D3
IMMUNE CELL B-CELLS Show tissue menu
B-CELLS DENDRITIC CELLS GRANULOCYTES MONOCYTES NK-CELLS PROGENITORS T-CELLS TOTAL PBMC
Immune cell proteome
B-cells
B-CELLS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA:586.0 nTPM
Monaco:2693.0 nTPM
Schmiedel:2529.3 TPM

B-CELLS - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM 586.0
HPA sample nTPM
Memory B-cell
nTPM: 586.0
Samples: 6

Max nTPM: 931.5
Min nTPM: 312.5
P10809_1017 312.5
P10809_1025 931.5
P10809_1044 460.8
P10809_1063 589.4
P10809_1092 541.7
P10809_1105 680.2
Naive B-cell
nTPM: 561.9
Samples: 6

Max nTPM: 696.8
Min nTPM: 302.5
P10809_1011 302.5
P10809_1029 671.6
P10809_1048 696.8
P10809_1067 530.0
P10809_1091 547.4
P10809_1104 623.0

B-CELLS - Monaco RNA-seqi

RNA-Seq data generated by Monaco et al is reported as average nTPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max nTPM 2693.0
Monaco sample nTPM
Exhausted memory B-cell
nTPM: 2579.7
Samples: 4

Max nTPM: 3085.9
Min nTPM: 1872.5
RHH5310_R3677 1872.5
RHH5218_R3590 2709.4
RHH5247_R3619 3085.9
RHH5276_R3648 2651.0
Naive B-cell
nTPM: 2693.0
Samples: 4

Max nTPM: 3497.0
Min nTPM: 2187.6
RHH5308_R3675 2187.6
RHH5216_R3588 3497.0
RHH5245_R3617 2771.9
RHH5274_R3646 2315.6
Non-switched memory B-cell
nTPM: 2366.4
Samples: 4

Max nTPM: 3148.2
Min nTPM: 1754.8
RHH5309_R3676 1754.8
RHH5217_R3589 2652.1
RHH5246_R3618 3148.2
RHH5275_R3647 1910.6
Plasmablast
nTPM: 799.7
Samples: 4

Max nTPM: 949.6
Min nTPM: 675.3
RHH5312_R3679 860.8
RHH5220_R3592 713.2
RHH5249_R3621 949.6
RHH5278_R3650 675.3
Switched memory B-cell
nTPM: 2408.6
Samples: 4

Max nTPM: 2977.2
Min nTPM: 1846.5
RHH5311_R3678 1846.5
RHH5219_R3591 2977.2
RHH5248_R3620 2557.7
RHH5277_R3649 2252.9

B-CELLS - Schmiedel RNA-seqi

RNA-Seq data generated by Schmiedel et al is reported as average TPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. TPM values of the individual samples are presented next to the box plot.

Max TPM 2529.3
Schmiedel sample id TPM
Naive B-cell
TPM: 2529.3
Samples: 91

Max TPM: 5633.2
Min TPM: 1131.1
B_CELL_NAIVE_1 5633.2
B_CELL_NAIVE_2 4525.1
B_CELL_NAIVE_3 4370.5
B_CELL_NAIVE_4 4309.2
B_CELL_NAIVE_5 4018.8
B_CELL_NAIVE_6 3497.3
B_CELL_NAIVE_7 3443.8
B_CELL_NAIVE_8 3283.5
B_CELL_NAIVE_9 3263.1
B_CELL_NAIVE_10 3260.0
B_CELL_NAIVE_11 3198.9
B_CELL_NAIVE_12 3178.9
B_CELL_NAIVE_13 3142.5
B_CELL_NAIVE_14 3110.6
B_CELL_NAIVE_15 3098.4
B_CELL_NAIVE_16 2987.6
B_CELL_NAIVE_17 2959.7
B_CELL_NAIVE_18 2956.6
B_CELL_NAIVE_19 2916.6
B_CELL_NAIVE_20 2879.9
B_CELL_NAIVE_21 2871.6
B_CELL_NAIVE_22 2748.3
B_CELL_NAIVE_23 2742.6
B_CELL_NAIVE_24 2734.6
B_CELL_NAIVE_25 2719.2
B_CELL_NAIVE_26 2700.3
B_CELL_NAIVE_27 2688.0
B_CELL_NAIVE_28 2678.5
B_CELL_NAIVE_29 2676.7
B_CELL_NAIVE_30 2670.3
B_CELL_NAIVE_31 2664.7
B_CELL_NAIVE_32 2663.7
B_CELL_NAIVE_33 2627.6
B_CELL_NAIVE_34 2618.6
B_CELL_NAIVE_35 2613.4
B_CELL_NAIVE_36 2603.0
B_CELL_NAIVE_37 2572.8
B_CELL_NAIVE_38 2562.5
B_CELL_NAIVE_39 2546.3
B_CELL_NAIVE_40 2528.4
B_CELL_NAIVE_41 2527.1
B_CELL_NAIVE_42 2500.7
B_CELL_NAIVE_43 2473.1
B_CELL_NAIVE_44 2460.3
B_CELL_NAIVE_45 2453.1
B_CELL_NAIVE_46 2449.2
B_CELL_NAIVE_47 2421.6
B_CELL_NAIVE_48 2384.3
B_CELL_NAIVE_49 2354.3
B_CELL_NAIVE_50 2332.1
B_CELL_NAIVE_51 2318.3
B_CELL_NAIVE_52 2295.9
B_CELL_NAIVE_53 2294.5
B_CELL_NAIVE_54 2291.3
B_CELL_NAIVE_55 2279.1
B_CELL_NAIVE_56 2272.0
B_CELL_NAIVE_57 2264.0
B_CELL_NAIVE_58 2224.0
B_CELL_NAIVE_59 2202.5
B_CELL_NAIVE_60 2194.0
B_CELL_NAIVE_61 2177.1
B_CELL_NAIVE_62 2161.2
B_CELL_NAIVE_63 2148.4
B_CELL_NAIVE_64 2147.2
B_CELL_NAIVE_65 2145.6
B_CELL_NAIVE_66 2143.8
B_CELL_NAIVE_67 2108.3
B_CELL_NAIVE_68 2108.0
B_CELL_NAIVE_69 2086.8
B_CELL_NAIVE_70 2075.5
B_CELL_NAIVE_71 2033.9
B_CELL_NAIVE_72 2026.6
B_CELL_NAIVE_73 2010.8
B_CELL_NAIVE_74 2004.7
B_CELL_NAIVE_75 1989.1
B_CELL_NAIVE_76 1975.9
B_CELL_NAIVE_77 1943.2
B_CELL_NAIVE_78 1938.9
B_CELL_NAIVE_79 1929.7
B_CELL_NAIVE_80 1929.2
B_CELL_NAIVE_81 1859.4
B_CELL_NAIVE_82 1850.2
B_CELL_NAIVE_83 1835.3
B_CELL_NAIVE_84 1834.9
B_CELL_NAIVE_85 1814.3
B_CELL_NAIVE_86 1790.7
B_CELL_NAIVE_87 1749.6
B_CELL_NAIVE_88 1692.5
B_CELL_NAIVE_89 1665.7
B_CELL_NAIVE_90 1603.3
B_CELL_NAIVE_91 1131.1
Show allShow less

Contact

  • NEWS ARTICLES
  • PRESS ROOM

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org