MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:7.3 nTPM
HPA Brain:77.7 nTPM
GTEx:7.3 nTPM
FANTOM5:2.5 Scaled Tags Per Million
Pig:17.4 nTPM
Mouse:43.8 nTPM
Allen mouse:4.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 77.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 45.8
2219 Male, age 76, both hemispheres 75.3
1827 Male, age 72, unknown 63.4
2666 Male, age 74, left hemisphere 49.1
2828 Female, age 72, unknown 46.0
2586 Male, age 75, left hemisphere 43.7
2411 Female, age 72, unknown 39.5
1833 Male, age 53, unknown 38.3
1830 Male, age 51, unknown 37.4
1870 Female, age 42, unknown 35.0
2019 Male, age 18, unknown 30.7
Dorsal raphe nucleus
nTPM: 39.2
2047 Male, age 72, unknown 53.2
2298 Female, age 72, unknown 47.4
2750 Male, age 76, both hemispheres 39.0
2016 Female, age 72, unknown 29.3
1828 Male, age 53, unknown 27.3
Inferior colliculus
nTPM: 77.7
2097 Female, age 72, unknown 107.7
2849 Male, age 72, unknown 72.5
1890 Male, age 53, unknown 68.5
1848 Female, age 42, unknown 62.3
Median raphe nucleus
nTPM: 57.2
2220 Male, age 76, midline 57.2
Periaquaductal grey, anterior
nTPM: 77.2
2502 Female, age 75, unknown 95.1
1947 Male, age 18, unknown 69.3
1795 Male, age 51, unknown 67.3
Periaquaductal grey, dorsal
nTPM: 53.7
1840 Male, age 53, unknown 64.6
2464 Female, age 72, unknown 58.8
1831 Male, age 72, unknown 49.0
2850 Male, age 76, both hemispheres 42.5
Periaquaductal grey, lateral
nTPM: 47.0
2053 Male, age 18, unknown 53.8
2140 Male, age 76, both hemispheres 53.2
2272 Male, age 74, both hemispheres 33.9
Pretectal area
nTPM: 54.6
1816 Male, age 51, unknown 75.8
1944 Female, age 72, unknown 60.9
2007 Male, age 72, unknown 60.5
2316 Male, age 76, right hemisphere 59.8
2825 Male, age 18, unknown 58.4
2407 Male, age 75, both hemispheres 56.1
2224 Female, age 72, unknown 52.9
2667 Female, age 75, unknown 51.6
1817 Female, age 42, unknown 47.6
1815 Male, age 53, unknown 46.7
2273 Male, age 74, both hemispheres 30.5
Red nucleus
nTPM: 32.1
2584 Male, age 75, left hemisphere 44.2
2785 Male, age 18, unknown 35.8
2503 Female, age 72, unknown 33.7
1954 Female, age 42, unknown 33.6
2823 Male, age 76, right hemisphere 32.8
2227 Male, age 72, unknown 32.4
2769 Male, age 72, unknown 30.1
2725 Female, age 75, unknown 29.9
2588 Male, age 74, left hemisphere 29.6
1904 Male, age 53, unknown 28.5
1865 Male, age 51, unknown 28.4
1821 Female, age 72, unknown 26.6
Substantia nigra
nTPM: 39.6
1941 Male, age 53, unknown 62.6
1916 Female, age 42, unknown 51.2
1889 Female, age 72, unknown 47.8
2665 Male, age 74, both hemispheres 46.7
2241 Male, age 72, unknown 39.2
1851 Male, age 51, unknown 36.8
2699 Male, age 18, unknown 33.8
2409 Female, age 72, unknown 29.1
2583 Male, age 75, right hemisphere 24.9
2590 Female, age 75, unknown 24.0
Superior colliculus
nTPM: 55.9
2664 Male, age 75, both hemispheres 77.5
1895 Male, age 76, right hemisphere 75.3
2668 Female, age 75, unknown 72.4
1796 Male, age 53, unknown 66.2
2261 Male, age 18, unknown 64.8
2087 Female, age 72, unknown 59.0
1839 Male, age 51, unknown 53.0
2587 Male, age 74, left hemisphere 36.2
1913 Female, age 42, unknown 28.1
1995 Male, age 72, unknown 26.1
Ventral tegmental area
nTPM: 43.1
2218 Male, age 76, both hemispheres 53.4
1942 Male, age 51, unknown 46.0
1915 Female, age 42, unknown 43.4
2223 Female, age 72, unknown 41.8
2021 Male, age 53, unknown 38.2
2410 Female, age 72, unknown 36.0

MIDBRAIN - GTEx RNA-seqi
Average nTPM 7.3
GTEx sample id Sample description nTPM
2.36.010.70.221.905101520253035
Brain - Substantia nigra
Average nTPM: 7.3
Samples: 139

Max nTPM: 39.3
Min nTPM: 0.2
Std nTPM: 6.2
Median nTPM: 6.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 39.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 27.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 23.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 21.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 20.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 19.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 19.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 18.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 18.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 18.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 15.9
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MIDBRAIN - FANTOM5 CAGEi
Max Scaled Tags Per Million 2.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 2.5
FF:10158-103A5 76 years, female 2.5

MIDBRAIN - Pig RNA-seqi
Average nTPM 17.4
Pig sample Sample description nTPM
6.29.111.13.611.501234567891011
 		Substantia nigra
nTPM: 8.3
Samples: 4

Max nTPM: 11.5
Min nTPM: 3.6
Sample A Female 11.0
Sample B Female 7.1
Sample C Male 11.5
Sample D Male 3.6
8.516.425.44.032.8051015202530
 		Midbrain
nTPM: 17.4
Samples: 4

Max nTPM: 32.8
Min nTPM: 4.0
Sample A Female 4.0
Sample B Female 10.0
Sample C Male 22.9
Sample D Male 32.8
9.09.811.48.213.0012345678910111213
 		Periaqueductal gray
nTPM: 10.3
Samples: 3

Max nTPM: 13.0
Min nTPM: 8.2
Sample B Female 9.8
Sample C Male 13.0
Sample D Male 8.2
14.517.919.38.019.5024681012141618
 		Superior colliculi
nTPM: 15.8
Samples: 4

Max nTPM: 19.5
Min nTPM: 8.0
Sample A Female 19.5
Sample B Female 8.0
Sample C Male 16.6
Sample D Male 19.2

MIDBRAIN - Mouse RNA-seqi
Average nTPM 43.8
Mouse sample Sample description nTPM
42.545.046.436.648.7051015202530354045
 		Midbrain
nTPM: 43.8
Samples: 4

Max nTPM: 48.7
Min nTPM: 36.6
Sample A Male 36.6
Sample B Male 45.6
Sample C Female 48.7
Sample D Female 44.4

MIDBRAIN - Allen Mouse ISHi
Max Expression energy 4.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.4
69289459 Antisense, RP_050407_03_C06, Mouse strain C57BL/6J (56 days, male) 8.7
71735078 Antisense, RP_050719_04_G10, Mouse strain C57BL/6J (56 days, male) 0.0

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