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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
11752.8
nTPM
HPA Brain:
27975.2
nTPM
GTEx:
11752.8
nTPM
Pig:
9315.4
nTPM
Mouse:
4169.0
nTPM
Allen mouse:
21.6
Expression energy
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
27975.2
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 19619.1
2586
Male, age 75, left hemisphere
31097.5
2219
Male, age 76, both hemispheres
30931.9
2666
Male, age 74, left hemisphere
25561.8
2828
Female, age 72, unknown
22396.9
1833
Male, age 53, unknown
18790.3
1870
Female, age 42, unknown
17263.8
1830
Male, age 51, unknown
17238.8
1827
Male, age 72, unknown
13321.8
2019
Male, age 18, unknown
11367.8
2411
Female, age 72, unknown
8220.1
Dorsal raphe nucleus nTPM: 11375.2
1828
Male, age 53, unknown
16734.6
2047
Male, age 72, unknown
13619.0
2750
Male, age 76, both hemispheres
12385.8
2016
Female, age 72, unknown
9510.5
2298
Female, age 72, unknown
4626.0
Inferior colliculus nTPM: 16290.6
2849
Male, age 72, unknown
29417.7
1890
Male, age 53, unknown
16124.9
1848
Female, age 42, unknown
13339.3
2097
Female, age 72, unknown
6280.6
Median raphe nucleus nTPM: 27975.2
2220
Male, age 76, midline
27975.2
Periaquaductal grey, anterior nTPM: 11359.6
2502
Female, age 75, unknown
14095.5
1795
Male, age 51, unknown
10265.6
1947
Male, age 18, unknown
9717.7
Periaquaductal grey, dorsal nTPM: 17139.3
2850
Male, age 76, both hemispheres
30331.9
1831
Male, age 72, unknown
14801.8
2464
Female, age 72, unknown
12250.5
1840
Male, age 53, unknown
11173.0
Periaquaductal grey, lateral nTPM: 10245.4
2140
Male, age 76, both hemispheres
14195.0
2053
Male, age 18, unknown
10539.7
2272
Male, age 74, both hemispheres
6001.4
Pretectal area nTPM: 15982.7
1816
Male, age 51, unknown
23370.5
1944
Female, age 72, unknown
22760.7
1817
Female, age 42, unknown
21674.1
2667
Female, age 75, unknown
21601.6
1815
Male, age 53, unknown
20742.7
2007
Male, age 72, unknown
16585.8
2825
Male, age 18, unknown
16402.8
2407
Male, age 75, both hemispheres
12248.4
2224
Female, age 72, unknown
8173.6
2316
Male, age 76, right hemisphere
6843.4
2273
Male, age 74, both hemispheres
5405.6
Red nucleus nTPM: 17522.2
2584
Male, age 75, left hemisphere
24732.8
2588
Male, age 74, left hemisphere
21965.5
2823
Male, age 76, right hemisphere
20530.5
2503
Female, age 72, unknown
20342.9
1954
Female, age 42, unknown
18848.3
1865
Male, age 51, unknown
17930.9
2785
Male, age 18, unknown
17203.0
2227
Male, age 72, unknown
15157.1
1904
Male, age 53, unknown
14835.9
2769
Male, age 72, unknown
14651.3
2725
Female, age 75, unknown
12650.2
1821
Female, age 72, unknown
11418.4
Substantia nigra nTPM: 19179.3
2665
Male, age 74, both hemispheres
36352.8
2699
Male, age 18, unknown
33485.1
1916
Female, age 42, unknown
22327.3
1941
Male, age 53, unknown
18848.4
2583
Male, age 75, right hemisphere
16467.9
1889
Female, age 72, unknown
15367.1
2590
Female, age 75, unknown
12767.6
2241
Male, age 72, unknown
12748.4
1851
Male, age 51, unknown
12171.0
2409
Female, age 72, unknown
11257.7
Superior colliculus nTPM: 15286.1
2664
Male, age 75, both hemispheres
27670.8
2087
Female, age 72, unknown
18215.7
2587
Male, age 74, left hemisphere
16135.8
1913
Female, age 42, unknown
15276.3
2668
Female, age 75, unknown
14489.4
1839
Male, age 51, unknown
13723.8
1895
Male, age 76, right hemisphere
12860.0
1995
Male, age 72, unknown
12343.8
2261
Male, age 18, unknown
11327.7
1796
Male, age 53, unknown
10817.3
Ventral tegmental area nTPM: 15274.4
2218
Male, age 76, both hemispheres
24690.6
2223
Female, age 72, unknown
17611.9
1942
Male, age 51, unknown
15207.0
1915
Female, age 42, unknown
12857.3
2021
Male, age 53, unknown
10981.2
2410
Female, age 72, unknown
10298.2
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
11752.8
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 11752.8
Samples: 139
Max nTPM: 48774.2
Min nTPM: 1755.3
Std nTPM: 8803.5
Median nTPM: 9186.8
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
4169.0
Mouse sample
Sample description
nTPM
Midbrain nTPM: 4169.1
Samples: 4
Max nTPM: 4304.2
Min nTPM: 3911.9
Sample A
Male
4304.2
Sample B
Male
4296.1
Sample C
Female
4164.0
Sample D
Female
3911.9
MIDBRAIN - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
The Human Protein Atlas project is funded
