In a publication in Genome Biology, HPA related researchers present an integrated resource that maps gene expression across the human body using both single cell and bulk RNA sequencing data. The study covers 31 tissues and identifies over 557 distinct cell clusters, each annotated and validated using known marker genes and antibody-based profiling...Read more

In a publication in Frontiers in Immunology HPA related researchers investigated the roles of macrophages and T cells in hepatocellular carcinoma (HCC)...Read more

Female fertility relies on the ovarian follicles that form during fetal development. Some medical treatments, such as chemo- or radiotherapy, are toxic to follicles and therefore ovarian tissue cryopreservation is used as a standard method for fertility preservation. This method is used for both adults and prepubertal individuals, even if its efficiency for tissue collected before puberty is not well documented...Read more

In a study published in the Journal of the Endocrine Society, transcriptomics analysis and radiological evaluation was used to explore the differences between invasive and noninvasive pituitary neuroendocrine tumors (PitNETs) with respect to parasellar growth, bone invasiveness and vascularization...Read more

In a study published in Nature Communications, the expression of all human protein-coding genes in more than 1,000 human cell lines representing 27 cancer types was investigated using genome-wide transcriptomics analysis...Read more