News ArticlesMultiplex tissue image of the month - FOXJ1 and HMGN3 in fallopian tubeIn this edition of multiplex tissue image of the month, the expression pattern of ciliogenesis-activating transcription factor FOXJ1 is contrasted with chromatin-regulating protein HMGN3 in fallopian tube...Read more ALDH18A1 and ferroptosis as a therapeutic target for cancer treatmentIn a recent study published in Nature it was discovered that the polyamine spermine acts as a chelator of intracellular iron and thus as a suppressor of ferroptosis. Spermine is a polyamine metabolite that is essential for cellular homeostasis, with known roles ranging from DNA stabilization and RNA processing to protein synthesis and ion channel regulation. Dysregulation of spermine metabolism is implicated in various malignant, neurodegenerative and inflammatory diseases...Read more Talking transcriptomicsIn this episode of Proteins Unfolded Evelina Sjöstedt, head of Single cell analysis at the Human Protein Atlas, joins the hosts PhD students Andrea Villanueva Raisman and Emilio Skarwan to explore the transcriptome, the bridge between our static DNA and active proteins...Read more The Proteomics Show with Cecilia LindskogIn the Episode 82 of of the Proteomics show podcast series "Alt Proteomics" HPA researcher Dr Cecilia Lindskog talks about the importance of proteomics data integration together with the hosts Benjamin Neely and Ben Orsburn...Read more Multiplex tissue image of the month - PKLR in kidneyGlycolysis-associated enzyme pyruvate kinase L/R (gene: PKLR) is here highlighted in specific tubular structures in the kidney using multiplex immunohistochemistry (mIHC/IF)...Read more |