The sub-ciliary localization of CIBAR2 in ciliated epithelium of the bronchus is visualized by multiplex immunohistochemistry (mIHC/IF)...Read more

With the recent release of version 24 of the Human Protein Atlas we provide a detailed map of 654 proteins that localize to a small, but important organelle, called the primary cilium. This tiny protrusion is present on most human cell types and serves as a cellular antenna, providing a compartment that is optimal for carefully sensing, transducing and relaying information from the extracellular environment...Read more

The mucus acinus-specific expression pattern of BPI fold containing family B member 2 (gene: BPIFB2) in salivary gland is highlighted by multiplex immunohistochemistry (mIHC/IF)...Read more

This week, we explore a fascinating protein that regulates the unfolded protein response (UPR) in eukaryotic cells in an unusual manner - by sensing the accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen and conveying this information to the nucleus. This is achieved through unconventional splicing of the XBP1 mRNA in the cytoplasm leading to the induction of a transcriptional program in the nucleus. Hence its apt name - Endoplasmic Reticulum to Nucleus Signaling, ERN1...Read more

The localization of Calaxin (gene: CLXN) in ciliated cells is highlighted in fallopian tube by multiplex immunohistochemistry (mIHC/IF)...Read more