This month, microtubule associated protein 6 (gene: MAP6) is highlighted in kidney glomeruli through multiplex immunohistochemistry (mIHC/IF)...Read more

Cancer-associated protein fetal and adult testis expressed 1 (gene: FATE1) is mapped to reproductive supporting cells in normal testis tissue using multiplex immunohistochemistry (mIHC/IF)...Read more

This month, the expression of beta-cell-associated transcription factor PDX1 within the endocrine pancreas is displayed through multiplex immunohistochemistry (mIHC/IF)...Read more

A new article in Protein Science describes the HPA Multiplex tissue resource, a spatial proteomics effort adding a new layer of high-resolution protein expression data to the HPA portal. The article presents both the methodology and the biological value of the resource, providing a scalable framework for in-depth spatial proteomics profiling of human tissues...Read more

A recent Molecular Systems Biology study used exploratory spatial proteomics to investigate early changes in high-grade serous ovarian cancer, including precursor lesions in the fallopian tube. In this interview by Gustav Ceder, Dr Fabian Coscia and Dr Mihnea-Paul Dragomir discuss how the team moved from spatial proteomics discovery to tissue-based validation using an Atlas Antibodies / Human Protein Atlas antibody against DHCR7...Read more