In a publication in Frontiers in Immunology HPA related researchers investigated the roles of macrophages and T cells in hepatocellular carcinoma (HCC)...Read more

A recent study published in Nature Communications has unveiled a complex landscape of autoantibodies emerging after SARS-CoV-2 infection. Researchers investigated the development of autoantibodies in a large cohort of healthcare workers and hospitalized COVID-19 patients, tracking their emergence and persistence over a 16-month period...Read more

The chemical exposome represents the sum of environmental chemical exposures throughout the life of an individual. These include exposure to chemicals from inhalation of polluted air, intake of dietary substances and pharmaceuticals, ingestion of contaminated food and water, but also to the metabolic products of gut microbiota. Chemical exposomes are readily measured in blood, but to conclusively link environmental exposures to disease etiology knowledge of their variability and longitudinal stability is required...Read more

Female fertility relies on the ovarian follicles that form during fetal development. Some medical treatments, such as chemo- or radiotherapy, are toxic to follicles and therefore ovarian tissue cryopreservation is used as a standard method for fertility preservation. This method is used for both adults and prepubertal individuals, even if its efficiency for tissue collected before puberty is not well documented...Read more

G-protein coupled receptors (GPCRs) are a large family of cell surface receptors important for activating cellular responses. They are activated by many types of signals like light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters and are involved in a wide range of diseases which have made them important drug targets. Receptor activity-modifying proteins (RAMPs) form complexes with the GPCRs and may regulate their cellular trafficking and pharmacology...Read more