Protein interactions for GOLGA2 - The Human Protein Atlas

GENERAL INFORMATIONⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	GOLGA2
Gene descriptionⁱ Full gene name according to HGNC.	Golgin A2
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.	Intracellular
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	15

HUMAN PROTEIN ATLAS INFORMATIONⁱ Summary of data presented in the Tissue section, with a representative image of protein expression (left) and an interactive chart showing the tissue-specific mRNA expression (right). The image and the chart are clickable and will redirect to more Tissue data. This section contains information regarding the expression profiles of protein-coding genes in normal human tissue, both on the mRNA and protein level. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry.
Tissue expression cluster (RNA)ⁱ The RNA data was used to cluster genes according to their expression across tissues. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity.	Non-specific - Ribosome (mainly)
Tissue specificity (RNA)ⁱ The RNA specificity category is based on mRNA expression levels in the consensus dataset which is calculated from the RNA expression levels in samples from HPA and GTEX. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected.	Low tissue specificity
Tau specificity score (RNA)ⁱ Tau specificity score is a numerical indicator of the specificity of the gene expression across cells or tissues. The value ranges from 0 and 1, where 0 indicates identical expression across all cells/tissue types, while 1 indicates expression in a single cell/tissue type.	0.20
Tissue distribution (RNA)ⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA and GTEX. The categories include: detected in all, detected in many, detected in some, detected in single and not detected.	Detected in all
Protein evidenceⁱ Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence (neXtProt evidence);and a Human Protein Atlas antibody- or RNA based score (HPA evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable. Read more	Evidence at protein level
Subcellular locationⁱ Main subcellular location based on data generated in the subcellular section of the Human Protein Atlas.	Localized to the Golgi apparatus
Secretome annotationⁱ All genes with at least one predicted secreted isoform have been annotated and classified with the aim to determine if the corresponding protein(s) are: secreted into blood locally secreted or actually being attached to membrane or retained in intracellular locations like mitochondria, endoplasmatic reticulum (ER), Golgi apparatus or lysosomes.	Not available

INTERACTION SUMMARYⁱ

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Subcell location

Predicted location

Tissue specificity

Protein class

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e.g. Brain enriched, Localized to mitochondria, Non-specific - Ribosome

Field

Cluster

Pathway

Number of interactions:

349

View all protein interaction data in IntAct

Interaction	Interaction type	Confidence	MI score	# Interactions
STK25	Physical association	High	0.95	10
PRKAB2	Physical association	High	0.88	126
CCNH	Physical association	High	0.87	37
PRPF31	Physical association	High	0.86	118
CDC73	Physical association	High	0.85	30
BCAS2	Physical association	High	0.84	49
RBM17	Physical association	High	0.83	21
GSE1	Physical association	High	0.83	15
GFAP	Physical association	High	0.81	147
NCF2	Physical association	High	0.81	8
GORASP2	Physical association	High	0.8	111
DAXX	Physical association	High	0.79	78
FAM90A1	Physical association	High	0.79	128
LENG1	Physical association	High	0.79	63
MORN3	Physical association	High	0.79	57
NTAQ1	Physical association	High	0.79	302
TCL1A	Physical association	High	0.79	34
YJU2	Physical association	High	0.79	15
ZBTB16	Physical association	High	0.79	43
C12orf50	Physical association	High	0.78	1
DCTN4	Physical association	High	0.78	8
FBXO28	Physical association	High	0.78	16
GPKOW	Physical association	High	0.78	40
KANK2	Physical association	High	0.78	151
KRT18	Physical association	High	0.78	26
KRT6A	Physical association	High	0.78	30
RAB2A	Physical association	High	0.78	15
ZNF414	Physical association	High	0.78	42
ZNF774	Physical association	High	0.78	68
PPP1R16B	Physical association	High	0.76	31
STK26	Physical association	High	0.76	8
ALKBH3	Physical association	High	0.74	5
TCF19	Physical association	High	0.74	12
TRIM29	Physical association	High	0.74	13
ARL4A	Physical association	High	0.72	6
ARPC3	Physical association	High	0.72	15
BARD1	Physical association	High	0.72	20
BYSL	Physical association	High	0.72	119
C2CD6	Physical association	High	0.72	44
CBX8	Physical association	High	0.72	78
CCAR1	Physical association	High	0.72	3
CCDC87	Physical association	High	0.72	7
CDC5L	Physical association	High	0.72	48
CDK18	Physical association	High	0.72	45
CEP57L1	Physical association	High	0.72	27
CHCHD2	Physical association	High	0.72	24
CINP	Physical association	High	0.72	32
DDX6	Physical association	High	0.72	66
FAM110A	Physical association	High	0.72	41
FAM50B	Physical association	High	0.72	39
GCC1	Physical association	High	0.72	37
GEM	Physical association	High	0.72	88
GLYCTK	Physical association	High	0.72	48
INPP5J	Physical association	High	0.72	15
KRT1	Physical association	High	0.72	32
LCP2	Physical association	High	0.72	16
LMO1	Physical association	High	0.72	88
LMO4	Physical association	High	0.72	85
MAGOH	Physical association	High	0.72	15
MAGOHB	Physical association	High	0.72	56
MFAP1	Physical association	High	0.72	79
MOS	Physical association	High	0.72	46
NME7	Physical association	High	0.72	62
NOS3	Physical association	High	0.72	40
PATL1	Physical association	High	0.72	15
PIN1	Physical association	High	0.72	112
PKN1	Physical association	High	0.72	59
PPP1R18	Physical association	High	0.72	68
PQBP1	Physical association	High	0.72	9
PSMA1	Physical association	High	0.72	135
RAB2B	Physical association	High	0.72	11
RAB39A	Physical association	High	0.72	5
RBM41	Physical association	High	0.72	23
RNF135	Physical association	High	0.72	4
RSPH14	Physical association	High	0.72	36
SH2D4A	Physical association	High	0.72	63
SLU7	Physical association	High	0.72	22
SMARCE1	Physical association	High	0.72	56
SNW1	Physical association	High	0.72	89
TCEA2	Physical association	High	0.72	88
TEAD4	Physical association	High	0.72	30
TFAP4	Physical association	High	0.72	13
TPX2	Physical association	High	0.72	8
TSSK3	Physical association	High	0.72	51
USP2	Physical association	High	0.72	78
WASHC3	Physical association	High	0.72	44
ZMAT2	Physical association	High	0.72	44
ZNF417	Physical association	High	0.72	140
BCL6	Physical association	High	0.7	40
FAM161A	Physical association	High	0.7	118
SCNM1	Physical association	High	0.7	148
TBC1D22B	Physical association	High	0.7	46
TRAF4	Physical association	High	0.7	73
UTP14C	Physical association	High	0.7	17
RHPN1	Physical association	High	0.67	15
C1orf35	Physical association	High	0.67	32
DCX	Physical association	High	0.67	13
GATA2	Physical association	High	0.67	24
GPANK1	Physical association	High	0.67	65
ITPKB	Physical association	High	0.67	8
KANSL1	Physical association	High	0.67	22
NEBL	Physical association	High	0.67	28
RAB39B	Physical association	High	0.67	4
RITA1	Physical association	High	0.67	3
SCAF8	Physical association	High	0.67	2
SCEL	Physical association	High	0.67	6
SH3RF2	Physical association	High	0.67	9
SLX9	Physical association	High	0.67	3
SPATA2	Physical association	High	0.67	17
THAP7	Physical association	High	0.67	47
UBE2U	Physical association	High	0.67	3
ZNF488	Physical association	High	0.67	10
CIC	Physical association	High	0.66	4
UBE2I	Physical association	High	0.66	40
ADAP1	Physical association	Medium	0.56	5
AFF4	Physical association	Medium	0.56	8
ALKBH2	Physical association	Medium	0.56	2
AQP1	Physical association	Medium	0.56	106
ARFIP2	Physical association	Medium	0.56	42
ARHGAP45	Physical association	Medium	0.56	8
ARHGEF6	Physical association	Medium	0.56	13
ATOSA	Physical association	Medium	0.56	5
ATOSB	Physical association	Medium	0.56	50
ATP5PO	Physical association	Medium	0.56	18
ATP6V1G1	Physical association	Medium	0.56	8
AXIN1	Physical association	Medium	0.56	40
BAHD1	Physical association	Medium	0.56	54
BAZ2B	Physical association	Medium	0.56	9
C1orf109	Physical association	Medium	0.56	121
CAB39	Physical association	Medium	0.56	10
CAPN7	Physical association	Medium	0.56	12
CCDC120	Physical association	Medium	0.56	90
CCDC13	Physical association	Medium	0.56	37
CCDC150	Physical association	Medium	0.56	3
CCDC17	Physical association	Medium	0.56	3
CCDC185	Physical association	Medium	0.56	34
CCDC198	Physical association	Medium	0.56	16
CCDC70	Physical association	Medium	0.56	11
CCNC	Physical association	Medium	0.56	69
CDC20B	Physical association	Medium	0.56	11
CDC37	Physical association	Medium	0.56	124
CDC7	Physical association	Medium	0.56	21
CDCA7L	Physical association	Medium	0.56	52
CDKL3	Physical association	Medium	0.56	22
CDKL5	Physical association	Medium	0.56	2
CDKN1A	Physical association	Medium	0.56	49
CENPP	Physical association	Medium	0.56	20
CEP95	Physical association	Medium	0.56	13
CHCHD3	Physical association	Medium	0.56	37
CLIP3	Physical association	Medium	0.56	5
CORO1A	Physical association	Medium	0.56	6
COX5B	Physical association	Medium	0.56	29
CRACR2A	Physical association	Medium	0.56	31
CUL5	Physical association	Medium	0.56	17
CWF19L2	Physical association	Medium	0.56	65
CYB5R2	Physical association	Medium	0.56	6
DEUP1	Physical association	Medium	0.56	34
DLGAP3	Physical association	Medium	0.56	6
DLGAP5	Physical association	Medium	0.56	3
DMTN	Physical association	Medium	0.56	3
DTX2	Physical association	Medium	0.56	95
EFHC1	Physical association	Medium	0.56	61
EIF3G	Physical association	Medium	0.56	12
ENKD1	Physical association	Medium	0.56	159
ENPP7	Physical association	Medium	0.56	4
ESCO2	Physical association	Medium	0.56	3
EXOC8	Physical association	Medium	0.56	67
EXOSC5	Physical association	Medium	0.56	42
FAM124B	Physical association	Medium	0.56	24
FAM161B	Physical association	Medium	0.56	54
FIP1L1	Physical association	Medium	0.56	5
FNDC11	Physical association	Medium	0.56	37
FOXC2	Physical association	Medium	0.56	7
GADD45GIP1	Physical association	Medium	0.56	55
GAS2L2	Physical association	Medium	0.56	29
GAS8	Physical association	Medium	0.56	97
GATAD2A	Physical association	Medium	0.56	5
GATAD2B	Physical association	Medium	0.56	19
GGN	Physical association	Medium	0.56	14
GNG5	Physical association	Medium	0.56	6
GNL3L	Physical association	Medium	0.56	13
GRB14	Physical association	Medium	0.56	3
GTPBP10	Physical association	Medium	0.56	3
HAUS1	Physical association	Medium	0.56	83
HDAC4	Physical association	Medium	0.56	22
HGS	Physical association	Medium	0.56	177
HOXB5	Physical association	Medium	0.56	47
HOXB9	Physical association	Medium	0.56	42
HTT	Physical association	Medium	0.56	665
HYCC2	Physical association	Medium	0.56	4
HYLS1	Physical association	Medium	0.56	1
IFT20	Physical association	Medium	0.56	24
IFT27	Physical association	Medium	0.56	16
IQUB	Physical association	Medium	0.56	56
ISCU	Physical association	Medium	0.56	16
ITGB5	Physical association	Medium	0.56	20
KAT5	Physical association	Medium	0.56	180
KDM1A	Physical association	Medium	0.56	86
KIFC3	Physical association	Medium	0.56	70
KRT6B	Physical association	Medium	0.56	20
KRT6C	Physical association	Medium	0.56	21
KRT75	Physical association	Medium	0.56	103
L3MBTL2	Physical association	Medium	0.56	36
LASP1	Physical association	Medium	0.56	21
LCOR	Physical association	Medium	0.56	5
LGALS3	Physical association	Medium	0.56	13
LIN7A	Physical association	Medium	0.56	12
LINGO1	Physical association	Medium	0.56	11
LMNB2	Physical association	Medium	0.56	22
LMO2	Physical association	Medium	0.56	61
LYPLA1	Physical association	Medium	0.56	2
LYSMD1	Physical association	Medium	0.56	10
MAB21L2	Physical association	Medium	0.56	11
MBD3	Physical association	Medium	0.56	14
MCM7	Physical association	Medium	0.56	25
MCRS1	Physical association	Medium	0.56	97
MISP	Physical association	Medium	0.56	44
MNAT1	Physical association	Medium	0.56	5
MORF4L1	Physical association	Medium	0.56	28
MORF4L2	Physical association	Medium	0.56	42
MSRB3	Physical association	Medium	0.56	4
MTFR2	Physical association	Medium	0.56	6
NDC80	Physical association	Medium	0.56	42
NDEL1	Physical association	Medium	0.56	60
NEFL	Physical association	Medium	0.56	70
NRIP1	Physical association	Medium	0.56	14
NUDT21	Physical association	Medium	0.56	20
NXT2	Physical association	Medium	0.56	10
ODAD4	Physical association	Medium	0.56	7
PARD6B	Physical association	Medium	0.56	19
PIAS2	Physical association	Medium	0.56	16
PID1	Physical association	Medium	0.56	9
PIK3R2	Physical association	Medium	0.56	21
PIMREG	Physical association	Medium	0.56	18
PITX1	Physical association	Medium	0.56	50
PKN3	Physical association	Medium	0.56	8
PKP4	Physical association	Medium	0.56	8
POLR3C	Physical association	Medium	0.56	29
POU4F3	Physical association	Medium	0.56	5
PPP1R26	Physical association	Medium	0.56	5
PRAM1	Physical association	Medium	0.56	17
PRKAA1	Physical association	Medium	0.56	33
PRKAA2	Physical association	Medium	0.56	78
PRPF18	Physical association	Medium	0.56	63
PRPF3	Physical association	Medium	0.56	35
PSMA4	Physical association	Medium	0.56	13
PTPN21	Physical association	Medium	0.56	17
RAD18	Physical association	Medium	0.56	12
RAMAC	Physical association	Medium	0.56	37
RANBP3L	Physical association	Medium	0.56	3
RBM22	Physical association	Medium	0.56	6
RBM25	Physical association	Medium	0.56	2
RCL1	Physical association	Medium	0.56	1
RCOR3	Physical association	Medium	0.56	24
RGS8	Physical association	Medium	0.56	1
RHNO1	Physical association	Medium	0.56	7
RHOJ	Physical association	Medium	0.56	16
RIBC1	Physical association	Medium	0.56	21
RIN1	Physical association	Medium	0.56	38
RNF169	Physical association	Medium	0.56	3
RTP5	Physical association	Medium	0.56	49
SAMD4A	Physical association	Medium	0.56	3
SAP30BP	Physical association	Medium	0.56	7
SECISBP2	Physical association	Medium	0.56	2
SELENOV	Physical association	Medium	0.56	9
SHC3	Physical association	Medium	0.56	31
SHISA6	Physical association	Medium	0.56	20
SMCP	Physical association	Medium	0.56	67
SMG9	Physical association	Medium	0.56	32
SNAP47	Physical association	Medium	0.56	21
SNF8	Physical association	Medium	0.56	19
SNRPB2	Physical association	Medium	0.56	16
SNX18	Physical association	Medium	0.56	14
SPATA18	Physical association	Medium	0.56	10
SPATA22	Physical association	Medium	0.56	16
SPG21	Physical association	Medium	0.56	129
STAC	Physical association	Medium	0.56	15
STAMBPL1	Physical association	Medium	0.56	22
SUDS3	Physical association	Medium	0.56	4
SYT17	Physical association	Medium	0.56	34
TAB2	Physical association	Medium	0.56	16
TCEANC	Physical association	Medium	0.56	24
TEPSIN	Physical association	Medium	0.56	101
TEX9	Physical association	Medium	0.56	6
TLE5	Physical association	Medium	0.56	105
TPM1	Physical association	Medium	0.56	7
TRIM14	Physical association	Medium	0.56	26
TRIM42	Physical association	Medium	0.56	112
TSGA10	Physical association	Medium	0.56	54
TSGA10IP	Physical association	Medium	0.56	83
TSHZ2	Physical association	Medium	0.56	15
TSHZ3	Physical association	Medium	0.56	24
TSSC4	Physical association	Medium	0.56	8
TTC23	Physical association	Medium	0.56	17
TTC9C	Physical association	Medium	0.56	14
TTPA	Physical association	Medium	0.56	36
TXLNA	Physical association	Medium	0.56	76
TXLNB	Physical association	Medium	0.56	61
UBE3C	Physical association	Medium	0.56	1
UBTFL1	Physical association	Medium	0.56	22
UTP23	Physical association	Medium	0.56	22
VEZF1	Physical association	Medium	0.56	40
VPS28	Physical association	Medium	0.56	12
VPS37C	Physical association	Medium	0.56	72
WHRN	Physical association	Medium	0.56	8
ZBTB4	Physical association	Medium	0.56	9
ZBTB42	Physical association	Medium	0.56	38
ZFP2	Physical association	Medium	0.56	10
ZGPAT	Physical association	Medium	0.56	25
ZNF124	Physical association	Medium	0.56	45
ZNF280C	Physical association	Medium	0.56	6
ZNF3	Physical association	Medium	0.56	11
ZNF35	Physical association	Medium	0.56	24
ZNF410	Physical association	Medium	0.56	10
ZNF438	Physical association	Medium	0.56	50
ZNF48	Physical association	Medium	0.56	14
ZNF512B	Physical association	Medium	0.56	10
ZNF524	Physical association	Medium	0.56	22
ZNF572	Physical association	Medium	0.56	58
ZNF581	Physical association	Medium	0.56	82
ZNF587	Physical association	Medium	0.56	102
ZNF648	Physical association	Medium	0.56	50
ZNF835	Physical association	Medium	0.56	54
ZZZ3	Physical association	Medium	0.56	8
AKAP9	Physical association	Medium	0.54	5
ZDHHC17	Physical association	Medium	0.51	30
ARID5A	Physical association	Medium	0.49	94
CCDC92	Physical association	Medium	0.49	7
CEP55	Physical association	Medium	0.49	56
COG6	Physical association	Medium	0.49	49
DNM2	Physical association	Medium	0.49	25
DVL2	Physical association	Medium	0.49	43
EAF2	Physical association	Medium	0.49	13
FANCG	Physical association	Medium	0.49	35
GGA2	Physical association	Medium	0.49	12
GMCL1	Physical association	Medium	0.49	50
GRAP2	Physical association	Medium	0.49	41
IHO1	Physical association	Medium	0.49	62
IKZF3	Physical association	Medium	0.49	130
NDUFA5	Physical association	Medium	0.49	9
SH3GLB2	Physical association	Medium	0.49	19
STN1	Physical association	Medium	0.49	16
SUPT5H	Physical association	Medium	0.49	8
TDP2	Physical association	Medium	0.49	6
TFIP11	Physical association	Medium	0.49	179
TRAF1	Physical association	Medium	0.49	166
TRAF5	Physical association	Medium	0.49	35
UBE2H	Physical association	Medium	0.49	9
XIAP	Physical association	Medium	0.49	42
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METABOLIC SUMMARYⁱ In this summary the pathway/subsystems to which the gene belongs is shown together with the associated cellular compartment for the reactions based on metabolite information. The number of proteins and metabolites in the pathway is shown as well as the number of reactions for the selected gene. By clicking on a pathway in the summary table the associated metabolic network map is shown, together with a gene-tissue heatmap that shows the expression of genes in that pathway in different tissues.
GOLGA2 is not a metabolic protein